A new systematic review published in the British Journal of Nutrition*, is one of the first to focus on patterns of vitamin D status worldwide and in key population subgroups, using continuous values for 25(OH)D to improve comparisons.
Principal investigator, Dr. Kristina Hoffmann of the Mannheim Institute of Public Health (MIPH), Medical Faculty Mannheim, Heidelberg University stated, “The strength of our study is that we used strict inclusion criteria to filter and compare data, using consistent values for 25(OH)D. Although we found a high degree of variability between reports of vitamin D status at the population level, more than one-third of the studies reviewed reported mean serum 25(OH)D values below 50 nmol/l.”
Low levels of vitamin D have a potentially serious impact on health, particularly on bone and muscle health. In children, vitamin D deficiency is a cause of rickets; while in adults low values are associated with osteomalacia, osteopenia, osteoporosis and risk of fracture. Emerging evidence also points to increased risk for cancer and cardiovascular diseases. Yet despite its importance to public health, data about vitamin D status at the population level are limited and studies are hampered by lack of consensus and consistency.
The study’s key findings include:
37.3% of the studies reviewed reported mean serum 25(OH)D values below 50 nmol/l, values considered inadequate by health authorities worldwide.
Only a limited number of studies for Latin America were available.
Vitamin D values were higher in North America than in Europe or the Middle-East.
Age-related differences were observed for the Asia-Pacific and Middle East regions, but not elsewhere.
The substantial heterogeneity between the studies within each region precludes drawing conclusions on overall vitamin D status at the population level.
There is a need for research designs which minimize potential sources of bias and thus strengthen understanding of vitamin D status in key subgroups worldwide.
International Osteoporosis Foundation (IOF) CEO Judy Stenmark noted, “Given the global increase in the number of seniors and the almost fourfold increase in hip fractures due to osteoporosis since 1990, public health officials must address the impact of inadequate vitamin D status on fracture risk and overall health in their ageing populations as well as on children and adolescents. IOF urges further research as well as public health measures that would help to improve vitamin D status in these high-risk population groups.”* Hilger J, Friedel A, Herr R, Rausch T, Roos F, Wahl DA, Pierroz DD, Weber P, Hoffman K.
A systematic review of vitamin D status in populations worldwide. Br J Nutr 2013 [Epub ahead of print DOI: 10.1017/s0007114513001840].
About IOFThe International Osteoporosis Foundation (IOF) is the world's largest nongovernmental organization dedicated to the prevention, diagnosis and treatment of osteoporosis and related musculoskeletal diseases. IOF members, including committees of scientific researchers, leading companies, as well as more than 200 patient, medical and research societies, work together to make bone, joint and muscle health a worldwide heath care priority.
www.iofbonehealth.org / www.facebook.com/iofbonehealth / https://twitter.com/iofbonehealth
L. Misteli | EurekAlert!
Drought hits rivers first and more strongly than agriculture
06.09.2018 | Max-Planck-Institut für Biogeochemie
Landslides triggered by human activity on the rise
23.08.2018 | European Geosciences Union
Scientists at the Max Planck Institute for Polymer Research (MPI-P) in Mainz (Germany) together with scientists from Dresden, Leipzig, Sofia (Bulgaria) and Madrid (Spain) have now developed and characterized a novel, metal-organic material which displays electrical properties mimicking those of highly crystalline silicon. The material which can easily be fabricated at room temperature could serve as a replacement for expensive conventional inorganic materials used in optoelectronics.
Silicon, a so called semiconductor, is currently widely employed for the development of components such as solar cells, LEDs or computer chips. High purity...
Augsburg chemists present a new technology for compressing, storing and transporting highly volatile gases in porous frameworks/New prospects for gas-powered vehicles
Storage of highly volatile gases has always been a major technological challenge, not least for use in the automotive sector, for, for example, methane or...
When we put water in a freezer, water molecules crystallize and form ice. This change from one phase of matter to another is called a phase transition. While this transition, and countless others that occur in nature, typically takes place at the same fixed conditions, such as the freezing point, one can ask how it can be influenced in a controlled way.
We are all familiar with such control of the freezing transition, as it is an essential ingredient in the art of making a sorbet or a slushy. To make a cold...
Thin organic layers provide machines and equipment with new functions. They enable, for example, tiny energy recuperators. In future, these will be installed...
Das Zusammenspiel aus Struktur und Dynamik bestimmt die Funktion von Proteinen, den molekularen Werkzeugen der Zelle. Durch Fortschritte in der...
17.10.2018 | Event News
16.10.2018 | Event News
02.10.2018 | Event News
17.10.2018 | Trade Fair News
17.10.2018 | Life Sciences
17.10.2018 | Agricultural and Forestry Science