Restless legs syndrome is a sleep and movement disorder. People with the disorder have the urge to move their legs to stop uncomfortable sensations. The urge occurs when the person is at rest, in the evening, and is temporarily relieved by movement. In leg motor restlessness, people also have the urge to move their legs, but it is either not worse when they are at rest or during the evening or it does not go away when they move their legs.
Because restless legs syndrome and Parkinson’s disease both respond to the drug dopamine, researchers have looked for connections between the two disorders. Some studies have shown that people with Parkinson’s disease are more likely also to have restless legs syndrome than people who don’t have Parkinson’s disease. But those studies have looked at people with advanced cases of Parkinson’s who have taken dopamine drugs for many years.
The current study is the first to look at the issue in people who were recently diagnosed with Parkinson’s disease and have not yet taken any dopamine drugs. The Norwegian study compared 200 people with early Parkinson’s disease to 173 people of similar ages who did not have Parkinson’s disease.
The study found that restless legs syndrome was not significantly more common in people with Parkinson’s disease than it was in those without the disease. But people with Parkinson’s were nearly three times more likely to have leg motor restlessness than those without Parkinson’s. A total of 26 people with Parkinson’s disease and 10 people without the disease had leg motor restlessness.
“This finding could possibly be because people who have not yet taken dopamine for their Parkinson’s disease have a dopamine deficiency in their brains, which is similar to when people develop motor restlessness after taking antipsychotic drugs that block dopamine in the brain,” said study author Michaela D. Gjerstad, PhD, of Stavanger University Hospital in Norway and a Fellow of the American Academy of Neurology.
John Morgan, MD, PhD, of Georgia Health Sciences University in Augusta, who wrote an editorial regarding the study, said, “Time will tell whether the majority of these people with leg motor restlessness will go on to develop restless legs syndrome, or whether the restlessness improves after they start taking dopamine drugs. Further study of this group of people will be quite interesting.”
The study was supported by the Western Norwegian Regional Health Authority, the Norwegian Parkinson Disease Association and the Research Council of Norway.
The American Academy of Neurology, an association of more than 24,000 neurologists and neuroscience professionals, is dedicated to promoting the highest quality patient-centered neurologic care. A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as Alzheimer’s disease, stroke, migraine, multiple sclerosis, brain injury, Parkinson’s disease and epilepsy.
For more information about the American Academy of Neurology, visit http://www.aan.com
Rachel L. Seroka | American Academy of Neurology
Antarctic Ice Sheet mass loss has increased
14.06.2018 | Technische Universität Dresden
WAKE-UP provides new treatment option for stroke patients | International study led by UKE
17.05.2018 | Universitätsklinikum Hamburg-Eppendorf
In a recent publication in the renowned journal Optica, scientists of Leibniz-Institute of Photonic Technology (Leibniz IPHT) in Jena showed that they can accurately control the optical properties of liquid-core fiber lasers and therefore their spectral band width by temperature and pressure tuning.
Already last year, the researchers provided experimental proof of a new dynamic of hybrid solitons– temporally and spectrally stationary light waves resulting...
Scientists from the University of Freiburg and the University of Basel identified a master regulator for bone regeneration. Prasad Shastri, Professor of...
Moving into its fourth decade, AchemAsia is setting out for new horizons: The International Expo and Innovation Forum for Sustainable Chemical Production will take place from 21-23 May 2019 in Shanghai, China. With an updated event profile, the eleventh edition focusses on topics that are especially relevant for the Chinese process industry, putting a strong emphasis on sustainability and innovation.
Founded in 1989 as a spin-off of ACHEMA to cater to the needs of China’s then developing industry, AchemAsia has since grown into a platform where the latest...
The BMBF-funded OWICELLS project was successfully completed with a final presentation at the BMW plant in Munich. The presentation demonstrated a Li-Fi communication with a mobile robot, while the robot carried out usual production processes (welding, moving and testing parts) in a 5x5m² production cell. The robust, optical wireless transmission is based on spatial diversity; in other words, data is sent and received simultaneously by several LEDs and several photodiodes. The system can transmit data at more than 100 Mbit/s and five milliseconds latency.
Modern production technologies in the automobile industry must become more flexible in order to fulfil individual customer requirements.
An international team of scientists has discovered a new way to transfer image information through multimodal fibers with almost no distortion - even if the fiber is bent. The results of the study, to which scientist from the Leibniz-Institute of Photonic Technology Jena (Leibniz IPHT) contributed, were published on 6thJune in the highly-cited journal Physical Review Letters.
Endoscopes allow doctors to see into a patient’s body like through a keyhole. Typically, the images are transmitted via a bundle of several hundreds of optical...
13.06.2018 | Event News
08.06.2018 | Event News
05.06.2018 | Event News
22.06.2018 | Materials Sciences
22.06.2018 | Earth Sciences
22.06.2018 | Life Sciences