Before undergoing elective surgery, patients should consider waiting longer after a heart attack than is currently recommended, according to a study scheduled for publication in the May issue of the journal, Annals of Surgery.
The American Heart Association and the American College of Cardiology recommend patients wait at least four to six weeks after a heart attack before undergoing elective surgery. This guidance is based on studies conducted in the 1970s and 1980s.
The new study examined surgical outcomes among more than 550,000 California patients over a five-year period (1999-2004) who underwent five common elective surgeries after a heart attack. Researchers found substantially lower death rates and fewer subsequent heart attacks in those who waited eight or more weeks after a heart attack to undergo hip surgery, gallbladder removal, non-traumatic amputation, colon resection or elective abdominal aortic aneurysm repair.
"Despite medical advancements in the treatment of coronary artery disease today, a recent heart attack remains a very important risk factor for patients undergoing surgery," said Christian de Virgilio, MD, the study's corresponding author and a principal investigator at Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (LA BioMed). "Our study suggests that patients should wait at least eight weeks after a heart attack before undergoing elective surgery. The results of the study also reignite the question of whether, in this high risk group, physicians should consider coronary artery stenting or bypass prior to elective surgery."
Researchers found the risk of subsequent heart attacks and death generally declined the longer the time between a heart attack and elective surgery. For instance, the risk of death for heart attack in patients undergoing hip surgery declined nearly 40 percent when the surgery took place more than six months after the heart attack.
Among patients who underwent hip surgery within 30 days of a heart attack, the study found 13.1 percent died within a month. Among those whose hip surgery occurred six months to one year after a heart attack, researchers found the death rate within a month was 7.9 percent. The risk of a subsequent heart attack went from 38.4 percent for hip surgery performed within a month of a heart attack to 6.2 percent for hip surgery performed six months to a year after a heart attack.
"Our research examined a much wider range of patients and surgeries than in past studies, and it points out the importance of a recent heart attack in determining the timing for elective surgeries," said Dr. de Virgilio.
About LA BioMed
Founded in 1952, LA BioMed is one of the country's leading nonprofit independent biomedical research institutes. It has more than 150 principal researchers conducting studies into improved treatments and cures for cancer, inherited diseases, infectious diseases, illnesses caused by environmental factors and more. It also educates young scientists and provides community services, including immunization and childhood nutrition programs. LA BioMed is academically affiliated with the David Geffen School of Medicine at UCLA and located on the campus of Harbor-UCLA Medical Center. For more information, please visit www.LABioMed.org
Laura Mecoy | EurekAlert!
Further reports about: > BioMed > Harbor-UCLA > Heart Attack > Medical Wellness > colon resection > coronary artery disease > death rate > elective abdominal aortic aneurysm repair > elective surgery > gallbladder removal > heart attacks > hip surgery > non-traumatic amputation > outcomes > surgical outcomes
Study relating to materials testing Detecting damages in non-magnetic steel through magnetism
23.07.2018 | Technische Universität Kaiserslautern
Innovative genetic tests for children with developmental disorders and epilepsy
11.07.2018 | Christian-Albrechts-Universität zu Kiel
New design tool automatically creates nanostructure 3D-print templates for user-given colors
Scientists present work at prestigious SIGGRAPH conference
Most of the objects we see are colored by pigments, but using pigments has disadvantages: such colors can fade, industrial pigments are often toxic, and...
Scientists at the University of California, Los Angeles present new research on a curious cosmic phenomenon known as "whistlers" -- very low frequency packets...
Scientists develop first tool to use machine learning methods to compute flow around interactively designable 3D objects. Tool will be presented at this year’s prestigious SIGGRAPH conference.
When engineers or designers want to test the aerodynamic properties of the newly designed shape of a car, airplane, or other object, they would normally model...
Researchers from TU Graz and their industry partners have unveiled a world first: the prototype of a robot-controlled, high-speed combined charging system (CCS) for electric vehicles that enables series charging of cars in various parking positions.
Global demand for electric vehicles is forecast to rise sharply: by 2025, the number of new vehicle registrations is expected to reach 25 million per year....
Proteins must be folded correctly to fulfill their molecular functions in cells. Molecular assistants called chaperones help proteins exploit their inbuilt folding potential and reach the correct three-dimensional structure. Researchers at the Max Planck Institute of Biochemistry (MPIB) have demonstrated that actin, the most abundant protein in higher developed cells, does not have the inbuilt potential to fold and instead requires special assistance to fold into its active state. The chaperone TRiC uses a previously undescribed mechanism to perform actin folding. The study was recently published in the journal Cell.
Actin is the most abundant protein in highly developed cells and has diverse functions in processes like cell stabilization, cell division and muscle...
17.08.2018 | Event News
08.08.2018 | Event News
27.07.2018 | Event News
17.08.2018 | Physics and Astronomy
17.08.2018 | Information Technology
17.08.2018 | Life Sciences