Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Mandibular movement monitoring may help improve oral sleep apnea devices

06.11.2018

Tracking jaw movements is a useful tool for measuring the efficacy of oral appliances, according to a new study in the journal CHEST®

While continuous positive airway pressure (CPAP) continues to be the gold standard for treatment of sleep apnea, the cumbersome machines are often not well tolerated by patients.


This is a chart showing the changes from baseline found in subjects during the study.

Credit: CHEST

Because of this, less obtrusive oral appliances that thrust the jaw forward during sleep are becoming more popular. Mandibular protrusion enlarges the pharynx and stabilizes the upper airway. A new study in CHEST® demonstrates that mandibular movements (MM) monitoring can be used to assess the efficacy of these oral appliances.

MM during sleep are accurate reporters for increased respiratory effort and micro arousals found in people with sleep apnea. In this sleep study, 56 patients with obstructive sleep apnea (OSA) were fitted with a custom mandibular advancement splint (OAT) and had their midsagittal mandibular movement tracked.

Patients were evaluated at the end of the titration procedure. During the titration procedure different degrees of advancement are trialed up and down to find the single best amount to control apnea events for that patient.

"The novelty of the study related to tracking sleep MM in order to assess oral appliance therapy effectiveness," explained lead investigator Jean-Benoit Martinot, MD, Sleep Laboratory, CHU UCL Namur Site Sainte-Elisabeth, Namur, Belgium. "Our study suggested for the first time that MM monitoring represents a powerful tool for assessing the efficacy of OAT treatment."

Investigators found that by the end of titration, all indications of OSA decreased compared with baseline. Overall, patients showed a reduction of vertical respiratory MM and sleep respiratory effort, as well as a dramatic decrease in obstructive hypopnea. Scores from the apnea-hypopnea index and oxygen desaturation index also dropped.

"Using MM measurements in the oral appliance titration procedure has the potential to optimize the benefit/risk ratio of oral appliances," said Dr. Martinot. "There is a high interindividual variability in response to the oral appliances, and it is difficult to predict the range of responses without proper measurement."

Researchers also found that MM monitoring helped to reveal the presence of central apneas. They found in a subgroup of subjects a decrease in respiratory effort, but no improvement or an increase in sharp and sudden MM of high amplitude, which indicates persistent sleep fragmentation. This is highly suggestive of emergent central apneas and may shed light on a possible predictor for poor response to OAT.

With new technology on the horizon, MM monitoring could potentially represent a cost-effective and easy-to-implement tool for sleep clinics to use when titrating oral appliances.

"MM monitoring during sleep is practical and informative for measuring indices of residual respiratory events when OSA is treated by oral appliances," concluded Dr. Martinot. "Given the growing use of this treatment as the primary alternative to CPAP, these data are relevant for sleep clinicians.

Media Contact

Andrea Camino
acamino@chestnet.org
224-521-9513

 @elseviernews

http://www.elsevier.com 

Andrea Camino | EurekAlert!

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Electrons in the fast lane

Solar cells based on perovskite compounds could soon make electricity generation from sunlight even more efficient and cheaper. The laboratory efficiency of these perovskite solar cells already exceeds that of the well-known silicon solar cells. An international team led by Stefan Weber from the Max Planck Institute for Polymer Research (MPI-P) in Mainz has found microscopic structures in perovskite crystals that can guide the charge transport in the solar cell. Clever alignment of these "electron highways" could make perovskite solar cells even more powerful.

Solar cells convert sunlight into electricity. During this process, the electrons of the material inside the cell absorb the energy of the light....

Im Focus: The lightest electromagnetic shielding material in the world

Empa researchers have succeeded in applying aerogels to microelectronics: Aerogels based on cellulose nanofibers can effectively shield electromagnetic radiation over a wide frequency range – and they are unrivalled in terms of weight.

Electric motors and electronic devices generate electromagnetic fields that sometimes have to be shielded in order not to affect neighboring electronic...

Im Focus: Gentle wall contact – the right scenario for a fusion power plant

Quasi-continuous power exhaust developed as a wall-friendly method on ASDEX Upgrade

A promising operating mode for the plasma of a future power plant has been developed at the ASDEX Upgrade fusion device at Max Planck Institute for Plasma...

Im Focus: ILA Goes Digital – Automation & Production Technology for Adaptable Aircraft Production

Live event – July 1, 2020 - 11:00 to 11:45 (CET)
"Automation in Aerospace Industry @ Fraunhofer IFAM"

The Fraunhofer Institute for Manufacturing Technology and Advanced Materials IFAM l Stade is presenting its forward-looking R&D portfolio for the first time at...

Im Focus: AI monitoring of laser welding processes - X-ray vision and eavesdropping ensure quality

With an X-ray experiment at the European Synchrotron ESRF in Grenoble (France), Empa researchers were able to demonstrate how well their real-time acoustic monitoring of laser weld seams works. With almost 90 percent reliability, they detected the formation of unwanted pores that impair the quality of weld seams. Thanks to a special evaluation method based on artificial intelligence (AI), the detection process is completed in just 70 milliseconds.

Laser welding is a process suitable for joining metals and thermoplastics. It has become particularly well established in highly automated production, for...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

International conference QuApps shows status quo of quantum technology

02.07.2020 | Event News

Dresden Nexus Conference 2020: Same Time, Virtual Format, Registration Opened

19.05.2020 | Event News

Aachen Machine Tool Colloquium AWK'21 will take place on June 10 and 11, 2021

07.04.2020 | Event News

 
Latest News

Coupled hair cells in the inner ear – „Together we are strong!“

06.07.2020 | Health and Medicine

Innovations for sustainability in a post-pandemic future

06.07.2020 | Social Sciences

Carbon-loving materials designed to reduce industrial emissions

06.07.2020 | Materials Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>