Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Link between paracetamol use and asthma in European adults confirmed in GA²LEN study

17.09.2008
Adults who take paracetamol weekly were nearly three times more likely to have asthma than those taking paracetamol less often, according to a study organised by GA²LEN, the Global Allergy and Asthma European Network. Use of other painkillers was not significantly related to asthma.

In the GA²LEN-SARI study, published in the European Respiratory Journal, researchers across Europe compared the frequency of analgesic use in over 500 adults with asthma and over 500 controls. Their results, to be presented at the next Annual Congress of the European Respiratory Society (ERS) in Berlin (October 4-8, 2008) suggest that the risk of asthma symptoms is increased by frequent paracetamol use.

This may be the consequence of the action of paracetamol that reduces levels of ‘glutathione’ in the lungs, an antioxidant substance needed to defend the airways against damage from air pollution and tobacco smoke.

Dr Seif Shaheen from Imperial College London, one of the authors of the study, says “Epidemiological evidence is growing that shows a link between paracetamol and asthma. Since 2000, several publications have reported this association for instance in the UK and the USA. We have also shown that asthma prevalence is higher in children and adults in countries with higher paracetamol sales.”

“Considering asthma is a common disease and paracetamol use is frequent, it is now important to find out whether this association is really a causal one. A clinical trial may be the only way to answer this question conclusively.”

The Selenium and Asthma Research Integration (SARI) project was initially set out across 15 GA²LEN centres to integrate research efforts and build capacity of the GA²LEN network for future large epidemiological studies. The network is also developing a clinical trial network specialised in allergy and asthma, which in the long run could help scientists to further investigate the link between paracetamol and asthma.

Dr. Seif Shaheen | alfa
Further information:
http://www.ga2len.net

Further reports about: Asthma ERS GA²LEN Paracetamol Respiratory glutathione painkillers

More articles from Studies and Analyses:

nachricht Researchers simplify tiny structures' construction drip by drip
12.11.2018 | Princeton University, Engineering School

nachricht Mandibular movement monitoring may help improve oral sleep apnea devices
06.11.2018 | Elsevier

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Nonstop Tranport of Cargo in Nanomachines

Max Planck researchers revel the nano-structure of molecular trains and the reason for smooth transport in cellular antennas.

Moving around, sensing the extracellular environment, and signaling to other cells are important for a cell to function properly. Responsible for those tasks...

Im Focus: UNH scientists help provide first-ever views of elusive energy explosion

Researchers at the University of New Hampshire have captured a difficult-to-view singular event involving "magnetic reconnection"--the process by which sparse particles and energy around Earth collide producing a quick but mighty explosion--in the Earth's magnetotail, the magnetic environment that trails behind the planet.

Magnetic reconnection has remained a bit of a mystery to scientists. They know it exists and have documented the effects that the energy explosions can...

Im Focus: A Chip with Blood Vessels

Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.

Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...

Im Focus: A Leap Into Quantum Technology

Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.

In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...

Im Focus: Research icebreaker Polarstern begins the Antarctic season

What does it look like below the ice shelf of the calved massive iceberg A68?

On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Optical Coherence Tomography: German-Japanese Research Alliance hosted Medical Imaging Conference

19.11.2018 | Event News

“3rd Conference on Laser Polishing – LaP 2018” Attracts International Experts and Users

09.11.2018 | Event News

On the brain’s ability to find the right direction

06.11.2018 | Event News

 
Latest News

Nonstop Tranport of Cargo in Nanomachines

20.11.2018 | Life Sciences

Researchers find social cultures in chimpanzees

20.11.2018 | Life Sciences

When AI and optoelectronics meet: Researchers take control of light properties

20.11.2018 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>