Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

High Estrogen Levels, Diabetes Together May Increase Dementia Risk 14-Fold in Older Women

30.01.2014
Older women who have high estrogen levels and diabetes may have a 14 times increased risk of dementia, according to a new study published in the January 29, 2014, online issue of Neurology®, the medical journal of the American Academy of Neurology.

Blood estrogens were measured in women free of dementia aged 65 or older. After a four-year follow-up, 543 women who did not have dementia were compared with 132 women who had dementia. Scientists looked at a number of risk factors for dementia, including diabetes, high blood pressure, abnormal blood clotting and other heart health risk factors.

The study found that the risk of dementia more than doubled for women who had high estrogen levels after accounting for other dementia risk factors. For those who had high estrogen levels and diabetes, the risk for dementia increased dramatically, by 14 times.

Estrogen levels were about 70 percent higher in women with diabetes who also had dementia compared to those without dementia. No other heart health risk factors raised the dementia risk.

“These results are surprising, given the expected brain protective effects of estrogen-based therapy,” said study author Pierre-Yves Scarabin, MD, with the French National Institute of Health and Medical Research (INSERM) in Villejuif, France. “However, more and more evidence suggests an association between high estradiol levels and dementia in women who have undergone menopause. Considering the expected increase in the number of elderly people with diabetes and dementia, more research on this topic should be urgently conducted.”

The research was supported by INSERM, the Victor Segalen-Bordeaux II University, Sanofi-Aventis, Foundation for Medical Research, National Health Fund for Employees, Directorate General of Health, MGEN, Institute of Longevity, Regional Councils of Aquitaine and Bourgogne, Foundation of France, and the National Agency of Research.

To learn more about dementia, please visit www/aan.com/patients.

The American Academy of Neurology, an association of more than 27,000 neurologists and neuroscience professionals, is dedicated to promoting the highest quality patient-centered neurologic care. A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as Alzheimer’s disease, stroke, migraine, multiple sclerosis, brain injury, Parkinson’s disease and epilepsy.

For more information about the American Academy of Neurology, visit http://www.aan.com

Rachel L. Seroka | American Academy of Neurology
Further information:
http://www.aan.com

More articles from Studies and Analyses:

nachricht Novel study underscores microbial individuality
13.12.2019 | Bigelow Laboratory for Ocean Sciences

nachricht TU Dresden biologists examine sperm quality on the basis of their metabolism
29.11.2019 | Technische Universität Dresden

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Miniature double glazing: Material developed which is heat-insulating and heat-conducting at the same time

Styrofoam or copper - both materials have very different properties with regard to their ability to conduct heat. Scientists at the Max Planck Institute for Polymer Research (MPI-P) in Mainz and the University of Bayreuth have now jointly developed and characterized a novel, extremely thin and transparent material that has different thermal conduction properties depending on the direction. While it can conduct heat extremely well in one direction, it shows good thermal insulation in the other direction.

Thermal insulation and thermal conduction play a crucial role in our everyday lives - from computer processors, where it is important to dissipate heat as...

Im Focus: Fraunhofer IAF establishes an application laboratory for quantum sensors

In order to advance the transfer of research developments from the field of quantum sensor technology into industrial applications, an application laboratory is being established at Fraunhofer IAF. This will enable interested companies and especially regional SMEs and start-ups to evaluate the innovation potential of quantum sensors for their specific requirements. Both the state of Baden-Württemberg and the Fraunhofer-Gesellschaft are supporting the four-year project with one million euros each.

The application laboratory is being set up as part of the Fraunhofer lighthouse project »QMag«, short for quantum magnetometry. In this project, researchers...

Im Focus: How Cells Assemble Their Skeleton

Researchers study the formation of microtubules

Microtubules, filamentous structures within the cell, are required for many important processes, including cell division and intracellular transport. A...

Im Focus: World Premiere in Zurich: Machine keeps human livers alive for one week outside of the body

Researchers from the University Hospital Zurich, ETH Zurich, Wyss Zurich and the University of Zurich have developed a machine that repairs injured human livers and keep them alive outside the body for one week. This breakthrough may increase the number of available organs for transplantation saving many lives of patients with severe liver diseases or cancer.

Until now, livers could be stored safely outside the body for only a few hours. With the novel perfusion technology, livers - and even injured livers - can now...

Im Focus: SuperTIGER on its second prowl -- 130,000 feet above Antarctica

A balloon-borne scientific instrument designed to study the origin of cosmic rays is taking its second turn high above the continent of Antarctica three and a half weeks after its launch.

SuperTIGER (Super Trans-Iron Galactic Element Recorder) is designed to measure the rare, heavy elements in cosmic rays that hold clues about their origins...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

11th Advanced Battery Power Conference, March 24-25, 2020 in Münster/Germany

16.01.2020 | Event News

Laser Colloquium Hydrogen LKH2: fast and reliable fuel cell manufacturing

15.01.2020 | Event News

„Advanced Battery Power“- Conference, Contributions are welcome!

07.01.2020 | Event News

 
Latest News

A new 'cool' blue

17.01.2020 | Life Sciences

EU-project SONAR: Better batteries for electricity from renewable energy sources

17.01.2020 | Power and Electrical Engineering

Neuromuscular organoid: It’s contracting!

17.01.2020 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>