Elderly people with the metabolic syndrome—defined as having multiple risk factors associated with developing diabetes and heart disease—had an increased risk of chronic kidney disease, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).
An individual is diagnosed with the metabolic syndrome when they have three or more of the following risk factors for diabetes and heart disease: high abdominal obesity, low HDL ("good") cholesterol, high blood pressure, high triglycerides (fat in the blood) and high blood glucose levels. The metabolic syndrome is more common in older populations and while previous studies have demonstrated an association between the metabolic syndrome and kidney disease, the current study is the first to investigate this association as it applies to the elderly population.
"Our study found that metabolic syndrome predicts both the prevalence and incidence of chronic kidney disease in people aged 65 years or older," said lead investigator Chung-Jen Yen, MD, of National Taiwan University in Taipei, Taiwan. "We also found that rapid decline in renal function is more likely found in individuals with insulin resistance and high blood sugar levels."
In this study, researchers sought to define the effect of the metabolic syndrome and insulin resistance on the development of chronic kidney disease, and the decline in renal function in a cohort of 1,456 Asians aged 65 years or older. Yen and his colleagues evaluated study participants for the metabolic syndrome and insulin resistance, and followed them for an average of more than three years. They found that insulin resistance may be the central hub that links metabolic syndrome and the deterioration of renal function."Our study suggests that people can safeguard their kidneys when they take care of their blood glucose levels and lose weight," said Yen. "Further studies are needed to assess the impact of treating metabolic syndrome and insulin resistance on renal outcomes in the elderly population."
The article, "Metabolic syndrome and insulin resistance as risk factors for development of chronic kidney disease and rapid decline in renal function in the elderly" appears in the April 2012 issue of JCEM.
Founded in 1916, The Endocrine Society is the world's oldest, largest and most active organization devoted to research on hormones and the clinical practice of endocrinology. Today, The Endocrine Society's membership consists of over 15,000 scientists, physicians, educators, nurses and students in more than 100 countries. Society members represent all basic, applied and clinical interests in endocrinology. The Endocrine Society is based in Chevy Chase, Maryland. To learn more about the Society and the field of endocrinology, visit our site at www.endo-society.org. Follow us on Twitter at https://twitter.com/#!/EndoMedia.
Aaron Lohr | EurekAlert!
Researchers simplify tiny structures' construction drip by drip
12.11.2018 | Princeton University, Engineering School
Mandibular movement monitoring may help improve oral sleep apnea devices
06.11.2018 | Elsevier
Researchers at the University of New Hampshire have captured a difficult-to-view singular event involving "magnetic reconnection"--the process by which sparse particles and energy around Earth collide producing a quick but mighty explosion--in the Earth's magnetotail, the magnetic environment that trails behind the planet.
Magnetic reconnection has remained a bit of a mystery to scientists. They know it exists and have documented the effects that the energy explosions can...
Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.
Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...
Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.
In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...
On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.
When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure
Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...
09.11.2018 | Event News
06.11.2018 | Event News
23.10.2018 | Event News
16.11.2018 | Health and Medicine
16.11.2018 | Life Sciences
16.11.2018 | Life Sciences