Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Earlier onset of puberty in girls linked to obesity

04.11.2013
New research in Pediatrics shows obesity is the largest predictor of earlier onset puberty in girls, which is affecting white girls much sooner than previously reported.

Published online Nov. 4, the multi-institutional study strengthens a growing body of research documenting the earlier onset of puberty in girls of all races.

"The impact of earlier maturation in girls has important clinical implications involving psychosocial and biologic outcomes," said Frank Biro, MD, lead investigator and a physician in the Division of Adolescent Medicine at Cincinnati Children's Hospital Medical Center. "The current study suggests clinicians may need to redefine the ages for both early and late maturation in girls."

Girls with earlier maturation are at risk for a multitude of challenges, including lower self-esteem, higher rates of depression, norm-breaking behaviors and lower academic achievement. Early maturation also results in greater risks of obesity, hypertension and several cancers – including breast, ovarian and endometrial cancer.

The study was conducted through the Breast Cancer and Environmental Research Program, established by the National Institute of Environmental Health Science. Pediatrics is the journal of the American Academy of Pediatrics.

Researchers at centers in the San Francisco Bay Area, Cincinnati and New York City examined the ages of 1,239 girls at the onset of breast development and the impact of body mass index and race/ethnicity. The girls ranged in age from 6 to 8 years at enrollment and were followed at regular intervals from 2004 to 2011. Researchers used well-established criteria of pubertal maturation, including the five stages of breast development known as the Tanner Breast Stages.

The girls were followed longitudinally, which involved multiple regular visits for each girl. Researchers said this method provided a good perspective of what happened to each girl and when it occurred.

Researchers found the respective ages at the onset of breast development varied by race, body mass index (obesity), and geographic location. Breast development began in white, non-Hispanic girls, at a median age of 9.7 years, earlier than previously reported. Black girls continue to experience breast development earlier than white girls, at a median age of 8.8 years. The median age for Hispanic girls in the study was 9.3 years, and 9.7 years for Asian girls.

Body mass index was a stronger predictor of earlier puberty than race or ethnicity. Although the research team is still working to confirm the exact environmental and physiological factors behind the phenomenon, they conclude the earlier onset of puberty in white girls is likely caused by greater obesity.

Other institutions collaborating on the study include: Kaiser Permanente Division of Research, Oakland, Calif.; Mount Sinai School of Medicine, New York; California Department of Public Health and the University of California at Berkeley and San Francisco; and the University of Cincinnati College of Medicine.

Funding support for the study came from: the Breast Cancer and the Environment Research Program of the National Institute of Environmental Health Sciences and the National Cancer Institute (grant numbers U01ES012770, U01ES012771, U01ES012800, U01ES012801, U01ES019435, U01ES019453, U01ES019454, U01ES019457), with additional support from the National Institute of Environmental Health Sciences (P01ES009584, P30ES006096); the National Center for Research Resources (UL1RR024131, UL1RR029887, UL1RR026314); the Molecular Epidemiology in Children's Environmental Health training grant (T32-ES10957); and the Avon Foundation.

About Cincinnati Children's:

Cincinnati Children's Hospital Medical Center ranks third in the nation among all Honor Roll hospitals in U.S. News and World Report's 2013 Best Children's Hospitals ranking. It is ranked #1 for cancer and in the top 10 for nine of 10 pediatric specialties. Cincinnati Children's, a non-profit organization, is one of the top three recipients of pediatric research grants from the National Institutes of Health, and a research and teaching affiliate of the University of Cincinnati College of Medicine. The medical center is internationally recognized for improving child health and transforming delivery of care through fully integrated, globally recognized research, education and innovation. Additional information can be found at http://www.cincinnatichildrens.org. Connect on the Cincinnati Children's blog, via Facebook and on Twitter.

Nick Miller | EurekAlert!
Further information:
http://www.cchmc.org
http://www.cincinnatichildrens.org

More articles from Studies and Analyses:

nachricht Innovative genetic tests for children with developmental disorders and epilepsy
11.07.2018 | Christian-Albrechts-Universität zu Kiel

nachricht Oxygen loss in the coastal Baltic Sea is “unprecedentedly severe”
05.07.2018 | European Geosciences Union

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: First evidence on the source of extragalactic particles

For the first time ever, scientists have determined the cosmic origin of highest-energy neutrinos. A research group led by IceCube scientist Elisa Resconi, spokesperson of the Collaborative Research Center SFB1258 at the Technical University of Munich (TUM), provides an important piece of evidence that the particles detected by the IceCube neutrino telescope at the South Pole originate from a galaxy four billion light-years away from Earth.

To rule out other origins with certainty, the team led by neutrino physicist Elisa Resconi from the Technical University of Munich and multi-wavelength...

Im Focus: Magnetic vortices: Two independent magnetic skyrmion phases discovered in a single material

For the first time a team of researchers have discovered two different phases of magnetic skyrmions in a single material. Physicists of the Technical Universities of Munich and Dresden and the University of Cologne can now better study and understand the properties of these magnetic structures, which are important for both basic research and applications.

Whirlpools are an everyday experience in a bath tub: When the water is drained a circular vortex is formed. Typically, such whirls are rather stable. Similar...

Im Focus: Breaking the bond: To take part or not?

Physicists working with Roland Wester at the University of Innsbruck have investigated if and how chemical reactions can be influenced by targeted vibrational excitation of the reactants. They were able to demonstrate that excitation with a laser beam does not affect the efficiency of a chemical exchange reaction and that the excited molecular group acts only as a spectator in the reaction.

A frequently used reaction in organic chemistry is nucleophilic substitution. It plays, for example, an important role in in the synthesis of new chemical...

Im Focus: New 2D Spectroscopy Methods

Optical spectroscopy allows investigating the energy structure and dynamic properties of complex quantum systems. Researchers from the University of Würzburg present two new approaches of coherent two-dimensional spectroscopy.

"Put an excitation into the system and observe how it evolves." According to physicist Professor Tobias Brixner, this is the credo of optical spectroscopy....

Im Focus: Chemical reactions in the light of ultrashort X-ray pulses from free-electron lasers

Ultra-short, high-intensity X-ray flashes open the door to the foundations of chemical reactions. Free-electron lasers generate these kinds of pulses, but there is a catch: the pulses vary in duration and energy. An international research team has now presented a solution: Using a ring of 16 detectors and a circularly polarized laser beam, they can determine both factors with attosecond accuracy.

Free-electron lasers (FELs) generate extremely short and intense X-ray flashes. Researchers can use these flashes to resolve structures with diameters on the...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Leading experts in Diabetes, Metabolism and Biomedical Engineering discuss Precision Medicine

13.07.2018 | Event News

Conference on Laser Polishing – LaP: Fine Tuning for Surfaces

12.07.2018 | Event News

11th European Wood-based Panel Symposium 2018: Meeting point for the wood-based materials industry

03.07.2018 | Event News

 
Latest News

Subaru Telescope helps pinpoint origin of ultra-high energy neutrino

16.07.2018 | Physics and Astronomy

Barium ruthenate: A high-yield, easy-to-handle perovskite catalyst for the oxidation of sulfides

16.07.2018 | Life Sciences

New research calculates capacity of North American forests to sequester carbon

16.07.2018 | Earth Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>