Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

'Deadly diarrhea' rates nearly doubled in 10 years: Study

30.09.2014

Infections with the intestinal superbug C. difficile nearly doubled from 2001 to 2010 in U.S. hospitals without noticeable improvement in patient mortality rates or hospital lengths of stay, according to a study of 2.2 million C. difficile infection (CDI) cases published in the October issue of the American Journal of Infection Control, the official publication of the Association for Professionals in Infection Control and Epidemiology (APIC).

In this retrospective study from The University of Texas College of Pharmacy, researchers analyzed 10 years of data from the U.S. National Hospital Discharge Surveys (NHDS). From 2001 to 2010, rates of CDI among hospitalized adults rose from 4.5 to 8.2 CDI discharges per 1,000 total adult hospital discharges.

"Several factors may have contributed to the rise in CDI incidence in recent years," said Kelly Reveles, PharmD, PhD, lead author on the study. "Antibiotic exposure remains the most important risk factor for CDI."

According to the Centers for Disease Control and Prevention (CDC), C. difficile is the most common bacteria responsible for causing healthcare-associated infections in U.S. hospitals and is linked to 14,000 deaths each year. Reducing the use of high-risk, broad-spectrum antibiotics by 30 percent could lower CDI by 26 percent, estimates the CDC. The White House recently announced a new Executive Order and National Strategy for Combating Antibiotic-resistant Bacteria, which emphasized the need for antibiotic stewardship programs to help clinicians improve prescribing practices.

"It's been estimated that up to half of antibiotic use in humans is unnecessary," said APIC 2014 President Jennie Mayfield, BSN, MPH, CIC. "To make headway against CDI, hospitals and health facilities need to get serious about antibiotic stewardship."

According to The University of Texas College of Pharmacy study, most CDI patients were female (59 percent), white (86 percent), and more than 65 years of age (70 percent).

Of the 2.2 million adult CDI discharges, 33 percent had a principal diagnosis of CDI; 67 percent were classified as secondary CDI, meaning that CDI was not the primary reason they were hospitalized. Approximately 7.1 percent, or 154,184 patients, died during the study period.

"Our study found that peak CDI incidence occurred in 2008, with a slight decline through 2010," said Dr. Reveles. "The leveling off of CDI incidence toward the end of our study period may be the result of increased antibiotic stewardship programs and improved infection control measures, such as use of contact precautions, cleaning and disinfection of equipment, and environment, and hand hygiene."

According to a 2013 survey conducted by APIC, 60 percent of US hospitals had implemented antibiotic stewardship programs by 2013, up from 52 percent in 2010.

"With bugs like C. diff, it takes everyone asking – 'are these antibiotics really necessary?' to help curb inappropriate use and protect patients," said Mayfield.

Antibiotic resistance and stewardship is the theme of International Infection Prevention Week led by APIC, October 19-25, 2014. A free webinar and Twitter chat are being offered, along with an infographic poster for consumers on the "ABC's of antibiotics."

Liz Garman | Eurek Alert!
Further information:
http://www.elsevierhealth.com/

More articles from Studies and Analyses:

nachricht Researchers simplify tiny structures' construction drip by drip
12.11.2018 | Princeton University, Engineering School

nachricht Mandibular movement monitoring may help improve oral sleep apnea devices
06.11.2018 | Elsevier

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: UNH scientists help provide first-ever views of elusive energy explosion

Researchers at the University of New Hampshire have captured a difficult-to-view singular event involving "magnetic reconnection"--the process by which sparse particles and energy around Earth collide producing a quick but mighty explosion--in the Earth's magnetotail, the magnetic environment that trails behind the planet.

Magnetic reconnection has remained a bit of a mystery to scientists. They know it exists and have documented the effects that the energy explosions can...

Im Focus: A Chip with Blood Vessels

Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.

Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...

Im Focus: A Leap Into Quantum Technology

Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.

In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...

Im Focus: Research icebreaker Polarstern begins the Antarctic season

What does it look like below the ice shelf of the calved massive iceberg A68?

On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.

Im Focus: Penn engineers develop ultrathin, ultralight 'nanocardboard'

When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure

Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

“3rd Conference on Laser Polishing – LaP 2018” Attracts International Experts and Users

09.11.2018 | Event News

On the brain’s ability to find the right direction

06.11.2018 | Event News

European Space Talks: Weltraumschrott – eine Gefahr für die Gesellschaft?

23.10.2018 | Event News

 
Latest News

Purdue cancer identity technology makes it easier to find a tumor's 'address'

16.11.2018 | Health and Medicine

Good preparation is half the digestion

16.11.2018 | Life Sciences

Microscope measures muscle weakness

16.11.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>