Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Coronary CTA a cost-effective alternative to cardiac catheterization for the evaluation of CAD

22.04.2010
According to a study conducted at Thomas Jefferson University (TJU), non-invasive coronary computed tomography angiography (CTA) is a cost-effective alternative to invasive cardiac catheterization in the care of patients who have positive stress test results but a less than 50 percent chance of actually having significant coronary artery disease (CAD).

The study will be published in the May issue of the American Journal of Roentgenology (www.ajronline.org). CAD is a narrowing of the blood vessels that supply blood and oxygen to the heart. If left untreated, it can lead to a heart attack.

"Patients with positive stress test results but no heart-related symptoms, as well as patients with a positive stress test with atypical chest pain often receive referrals for cardiac catheterization for the evaluation of CAD," said the study's lead author, Ethan J. Halpern, M.D., professor, Department of Radiology at Jefferson Medical College, and director, Cardiac CT at Thomas Jefferson University Hospital. "Coronary CTA is an alternative, non-invasive diagnostic imaging test that can be used to effectively triage these patients."

The study compared the false-negative rates, false-positive rates, costs, and radiation exposure of direct referral of patients for cardiac catheterization with the values associated with performing coronary CTA before catheterization.

"At a 50 percent prevalence of CAD, we found that performing coronary CTA before cardiac catheterization results in an average cost saving of $789 per patient with a false-negative rate of 2.5 percent and average additional radiation exposure of 1-2 mSv, which is minimal," said Dr. Halpern.

According to the study results, when a patient with an expected CAD prevalence less than 85 percent is found to have a positive stress test result, coronary CTA is a less expensive alternative to direct performance of cardiac catheterization. Recent studies have demonstrated that diagnostic cardiac catheterization of patients with atypical symptoms will demonstrate significant CAD less than half of the time. If the pretest probability of CAD is low, the coronary CTA findings are more likely to obviate cardiac catheterization and thereby reduce both the cost and effective radiation dose of the workup.

The study's co-authors also from Jefferson are: David C. Levin, M.D., professor, Department of Radiology; and Michael Savage, M.D., associate professor, and David Fischman, M.D., associate professor, both of the Division of Cardiology in the Department of Medicine.

Ed Federico | EurekAlert!
Further information:
http://www.jefferson.edu

More articles from Studies and Analyses:

nachricht Innovative genetic tests for children with developmental disorders and epilepsy
11.07.2018 | Christian-Albrechts-Universität zu Kiel

nachricht Oxygen loss in the coastal Baltic Sea is “unprecedentedly severe”
05.07.2018 | European Geosciences Union

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Future electronic components to be printed like newspapers

A new manufacturing technique uses a process similar to newspaper printing to form smoother and more flexible metals for making ultrafast electronic devices.

The low-cost process, developed by Purdue University researchers, combines tools already used in industry for manufacturing metals on a large scale, but uses...

Im Focus: First evidence on the source of extragalactic particles

For the first time ever, scientists have determined the cosmic origin of highest-energy neutrinos. A research group led by IceCube scientist Elisa Resconi, spokesperson of the Collaborative Research Center SFB1258 at the Technical University of Munich (TUM), provides an important piece of evidence that the particles detected by the IceCube neutrino telescope at the South Pole originate from a galaxy four billion light-years away from Earth.

To rule out other origins with certainty, the team led by neutrino physicist Elisa Resconi from the Technical University of Munich and multi-wavelength...

Im Focus: Magnetic vortices: Two independent magnetic skyrmion phases discovered in a single material

For the first time a team of researchers have discovered two different phases of magnetic skyrmions in a single material. Physicists of the Technical Universities of Munich and Dresden and the University of Cologne can now better study and understand the properties of these magnetic structures, which are important for both basic research and applications.

Whirlpools are an everyday experience in a bath tub: When the water is drained a circular vortex is formed. Typically, such whirls are rather stable. Similar...

Im Focus: Breaking the bond: To take part or not?

Physicists working with Roland Wester at the University of Innsbruck have investigated if and how chemical reactions can be influenced by targeted vibrational excitation of the reactants. They were able to demonstrate that excitation with a laser beam does not affect the efficiency of a chemical exchange reaction and that the excited molecular group acts only as a spectator in the reaction.

A frequently used reaction in organic chemistry is nucleophilic substitution. It plays, for example, an important role in in the synthesis of new chemical...

Im Focus: New 2D Spectroscopy Methods

Optical spectroscopy allows investigating the energy structure and dynamic properties of complex quantum systems. Researchers from the University of Würzburg present two new approaches of coherent two-dimensional spectroscopy.

"Put an excitation into the system and observe how it evolves." According to physicist Professor Tobias Brixner, this is the credo of optical spectroscopy....

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Leading experts in Diabetes, Metabolism and Biomedical Engineering discuss Precision Medicine

13.07.2018 | Event News

Conference on Laser Polishing – LaP: Fine Tuning for Surfaces

12.07.2018 | Event News

11th European Wood-based Panel Symposium 2018: Meeting point for the wood-based materials industry

03.07.2018 | Event News

 
Latest News

A smart safe rechargeable zinc ion battery based on sol-gel transition electrolytes

20.07.2018 | Power and Electrical Engineering

Reversing cause and effect is no trouble for quantum computers

20.07.2018 | Information Technology

Princeton-UPenn research team finds physics treasure hidden in a wallpaper pattern

20.07.2018 | Materials Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>