Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Brain imaging demonstrates that former smokers have greater willpower

27.04.2011
Study highlights the importance of cognitive skills in exercising control over addictive drugs

A study, completed by researchers from Trinity College and the Research Institute for a Tobacco Free Society, Dublin, Ireland, compares former smokers to current smokers, and obtains insight into how to quit smoking might be discovered by studying the brains of those who have successfully managed to do so.

Functional MRI images were obtained while current smokers, former smokers and never smokers performed tasks designed to assess specific cognitive skills that were reasoned to be important for smoking abstinence. These included a response inhibition task to assess impulse control and the ability to monitor one's behavior and an attention task which assessed the ability to avoid distraction from smoking-related images, which tend to elicit an automatic attention response in smokers.

The investigators found that when doing these tasks, the current smokers compared to the never-smokers showed reduced functioning in prefrontal regions that are related to controlling behavior. In addition, the current smokers showed elevated activity in sub-cortical regions such as the nucleus accumbens that respond to the reward value or salience of the nicotine stimuli. However, in marked contrast, the former smokers did not show this sub-cortical activity, but instead showed increased activity in the frontal lobes – the areas that are critically involved in controlling behavior. Moreover, the former smokers were "super-normal", showing greater levels of activity in these prefrontal regions than the never-smokers.

The implication is that the brain regions responsible for what might be considered "willpower" show more activity in those who have quit smoking. This type of willpower can be measured, can be related to specific brain regions, and would appear to be related to being able to quit cigarettes. These results reinforce the value of smoking cessation therapies that stress the importance of, or that help to train, the cognitive skills involved in exercising control over drug desires.

"Differences in "bottom-up" and "top-down" neural activity in current and former cigarette smokers: Evidence for neural substrates which may promote nicotine abstinence through increased cognitive control" (Liam Nestor, Ella McCabe, Jennifer Jones, Luke Clancy, & Hugh Garavan) is published in NeuroImage http://dx.doi.org/10.1016/j.neuroimage.2011.03.054

Notes to Editors

The research, published in NeuroImage, was completed by Professor Hugh Garavan, Dr. Liam Nestor and colleagues at Trinity College, Dublin, Ireland and the Research Institute for a Tobacco Free Society, Dublin, Ireland.

The work was funded by the Royal City of Dublin Hospital Trust, Dublin, Ireland.

About Trinity College (TCIN) - Dublin

TCIN, founded in 2002, is based in Trinity College's Lloyd Institute where it operates in over 3,300 m2 of state-of-the-art research facilities that allow it to realise its 'molecules to mind' research mission. TCIN hosts approximately 45 Principal Investigators and their research groups from the disciplines of genetics, physiology, biochemistry, immunology, pharmacology, neurology, psychiatry, gerontology, psychology, engineering and physics, thereby enabling a novel multidisciplinary approach. Established in 1592, Trinity College Dublin is ranked in 52nd position in the top 100 world universities and 14th position in the top 200 European universities by the QS World University Rankings 2010. In the Times Higher Education World University Rankings for 2010 TCD is ranked 76th in the top 200 world universities and 15th in the top European universities.

About NeuroImage

NeuroImage, A Journal of Brain Function, provides a vehicle for communicating important advances, using imaging and modelling techniques to study structure-function relationships in the brain. The focus of NeuroImage is on brain systems; however, we are happy to consider papers dealing with structure and function at the microscopic level; if they inform the systems level. The main criterion, on which papers are judged, is to what extent does the scientific contribution advance our understanding of the mechanisms of brain function and how this function depends upon its structure and architecture. These mechanisms may operate in health and disease; therefore, NeuroImage welcomes clinical neuroscience papers that are framed to address mechanisms explicitly. The journal publishes original research articles, papers on methods or modelling, theory and position papers that describe the use of imaging approaches to studying the brain.

About Elsevier

Elsevier is a world-leading publisher of scientific, technical and medical information products and services. The company works in partnership with the global science and health communities to publish more than 2,000 journals, including The Lancet and Cell, and close to 20,000 book titles, including major reference works from Mosby and Saunders. Elsevier's online solutions include SciVerse ScienceDirect, SciVerse Scopus, Reaxys, MD Consult and Nursing Consult, which enhance the productivity of science and health professionals, and the SciVal suite and MEDai's Pinpoint Review, which help research and health care institutions deliver better outcomes more cost-effectively.

A global business headquartered in Amsterdam, Elsevier employs 7,000 people worldwide. The company is part of Reed Elsevier Group PLC, a world-leading publisher and information provider, which is jointly owned by Reed Elsevier PLC and Reed Elsevier NV. The ticker symbols are REN (Euronext Amsterdam), REL (London Stock Exchange), RUK and ENL (New York Stock Exchange).

Francesca Webb | EurekAlert!
Further information:
http://www.elsevier.com

Further reports about: Brain Elsevier Ireland NeuroImage PLC Rankings SciVerse Society TCIN Trinity brain region cognitive skills quit smoking

More articles from Studies and Analyses:

nachricht Antarctic Ice Sheet mass loss has increased
14.06.2018 | Technische Universität Dresden

nachricht WAKE-UP provides new treatment option for stroke patients | International study led by UKE
17.05.2018 | Universitätsklinikum Hamburg-Eppendorf

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Superconducting vortices quantize ordinary metal

Russian researchers together with their French colleagues discovered that a genuine feature of superconductors -- quantum Abrikosov vortices of supercurrent -- can also exist in an ordinary nonsuperconducting metal put into contact with a superconductor. The observation of these vortices provides direct evidence of induced quantum coherence. The pioneering experimental observation was supported by a first-ever numerical model that describes the induced vortices in finer detail.

These fundamental results, published in the journal Nature Communications, enable a better understanding and description of the processes occurring at the...

Im Focus: Temperature-controlled fiber-optic light source with liquid core

In a recent publication in the renowned journal Optica, scientists of Leibniz-Institute of Photonic Technology (Leibniz IPHT) in Jena showed that they can accurately control the optical properties of liquid-core fiber lasers and therefore their spectral band width by temperature and pressure tuning.

Already last year, the researchers provided experimental proof of a new dynamic of hybrid solitons– temporally and spectrally stationary light waves resulting...

Im Focus: Overdosing on Calcium

Nano crystals impact stem cell fate during bone formation

Scientists from the University of Freiburg and the University of Basel identified a master regulator for bone regeneration. Prasad Shastri, Professor of...

Im Focus: AchemAsia 2019 will take place in Shanghai

Moving into its fourth decade, AchemAsia is setting out for new horizons: The International Expo and Innovation Forum for Sustainable Chemical Production will take place from 21-23 May 2019 in Shanghai, China. With an updated event profile, the eleventh edition focusses on topics that are especially relevant for the Chinese process industry, putting a strong emphasis on sustainability and innovation.

Founded in 1989 as a spin-off of ACHEMA to cater to the needs of China’s then developing industry, AchemAsia has since grown into a platform where the latest...

Im Focus: First real-time test of Li-Fi utilization for the industrial Internet of Things

The BMBF-funded OWICELLS project was successfully completed with a final presentation at the BMW plant in Munich. The presentation demonstrated a Li-Fi communication with a mobile robot, while the robot carried out usual production processes (welding, moving and testing parts) in a 5x5m² production cell. The robust, optical wireless transmission is based on spatial diversity; in other words, data is sent and received simultaneously by several LEDs and several photodiodes. The system can transmit data at more than 100 Mbit/s and five milliseconds latency.

Modern production technologies in the automobile industry must become more flexible in order to fulfil individual customer requirements.

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Munich conference on asteroid detection, tracking and defense

13.06.2018 | Event News

2nd International Baltic Earth Conference in Denmark: “The Baltic Sea region in Transition”

08.06.2018 | Event News

ISEKI_Food 2018: Conference with Holistic View of Food Production

05.06.2018 | Event News

 
Latest News

Rapid water formation in diffuse interstellar clouds

25.06.2018 | Physics and Astronomy

Using tree-fall patterns to calculate tornado wind speed

25.06.2018 | Earth Sciences

'Stealth' material hides hot objects from infrared eyes

25.06.2018 | Power and Electrical Engineering

VideoLinks
Science & Research
Overview of more VideoLinks >>>