Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Body cooling cuts in-hospital cardiac arrest patient deaths nearly 12 percent, Mayo Clinic finds

20.04.2012
Forced body cooling known as therapeutic hypothermia has reduced in-hospital deaths among sudden cardiac arrest patients nearly 12 percent between 2001 and 2009, according to a Mayo Clinic study being presented at the upcoming American Academy of Neurology 2012 Annual Meeting in New Orleans. The research is among several Mayo abstracts that will be discussed at the conference.

The goal of therapeutic cooling is slowing the body's metabolism and preventing brain damage or death. It is believed that mild therapeutic hypothermia suppresses harmful chemical reactions in the brain and preserves cells. Two key studies published in 2002 found therapeutic hypothermia more effective for sudden cardiac arrest patients than traditional therapies.

Mayo researchers analyzed a database covering more than 1 million patients and found mortality rates among in-hospital sudden cardiac arrest patients dropped from 69.6 percent in 2001 -- the year before the studies appeared -- to 57.8 percent in 2009, the most recent data available.

"Because we reviewed such a large number of cases, we are confident that the reduction in mortality among in-hospital sudden cardiac arrest patients is significant and sustained," says co-author Alejandro Rabinstein, M.D., a Mayo Clinic neurologist. "We continue to seek answers to the questions: Why did this trend develop, and how can we accelerate it," says co-author Jennifer Fugate, D.O.

These measures are important because disease accumulates in the cortex over time, and inflammation in the cortex is a sign the disease has progressed.

Other studies being presented at AAN:

Structured resident sign-out during shift changes improves patient care: In the study, junior residents in Mayo Clinic's General Neurology, Stroke and Neurologic Intensive Care Units spent the first half of their rotations using unstructured sign-out approaches and transitioned to a structured system for the second half. The residents reported that the standardized sign-out improved communication substantially, including information on pertinent past medical history, pending lab tests, recommendations on how to handle nursing and pharmacy calls, and up-to-date code status. Residents using standardized sign-out were also more likely to share test results with patients and their families prior to shift changes. This led to a significant increase in overall satisfaction with the sign-out process.

"This study is particularly timely now, when residency programs are adjusting to new duty-hour restrictions established in 2010," says lead author Brian Moseley, M.D., a Mayo Clinic neurology resident and Assistant Professor of Neurology. "When you have hand-offs because of the duty restrictions, unless the communication is good, there is a lot of opportunity for error," says Jeffrey Britton, M.D., a Mayo Clinic neurologist and study co-author. "This structured method seems to both prevent the error, but also make the patient and their family feel comfortable that this important communication is happening," says Dr. Britton.

Medical costs rise significantly as patients move from normal cognition through mild cognitive impairment to full-blown dementia:

Researchers studied 3,591 patients ages 70 to 89 categorized into four groups: normal, mild cognitive impairment, newly discovered dementia and prevalent dementia. Mean medical care costs rose from $6,042 for people in the normal group to $11,678 per year for those with prevalent dementia. Compared to normal persons, annual costs were an average of $859 higher for persons with mild cognitive impairment; and compared to persons with mild cognitive impairment were an average $4,457 higher for persons with dementia.

"Data about medical costs across the full range of cognitive decline are essential for identifying cost-effective strategies to postpone and prevent the onset of Alzheimer's disease," says co-author Cynthia Leibson, Ph.D., a Mayo Clinic epidemiologist. "Building on these data, we next will consider nursing home costs associated with dementia and identify the risk factors that underlie the differences between individual patients and among cognitive categories."

Stroke prevention program helps patients reduce risk factors:

Patients in a stroke prevention program were likelier to follow a prescribed diet and exercise than those receiving traditional care, Mayo researchers found in a study supported by the American Heart Association. Sixty-one percent of patients in the physician-directed, nurse-based program reduced at least one major risk factor after one year, such as high blood pressure, diabetes, smoking or high blood cholesterol. Just 33 percent of patients receiving more traditional care improved over the same period. The patients studied had suffered an atherosclerotis stroke -- a stroke caused by a blocked blood vessel leading to or within the brain -- and were at high risk for a second stroke.

"The study shows that relatively modest changes to a traditional care model for chronic disease can make a major difference in the continued health of stroke patients," says co-author Kelly Flemming, M.D., a Mayo Clinic neurologist.

JOURNALISTS: Mayo Clinic experts will be available to reporters seeking comment on research presented at AAN. Please contact Brian Kilen at above contact info.

About Mayo Clinic

Mayo Clinic is a nonprofit worldwide leader in medical care, research and education for people from all walks of life. For more information, visit www.mayoclinic.org/about/ and www.mayoclinic.org/news

Brian Kilen | EurekAlert!
Further information:
http://www.mayo.edu

More articles from Studies and Analyses:

nachricht Deep Brain Stimulation Provides Sustained Relief for Severe Depression
19.03.2019 | Universitätsklinikum Freiburg

nachricht AI study of risk factors in type 1 diabetes
06.03.2019 | University of Gothenburg

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: New gene potentially involved in metastasis identified

Gene named after Roman goddess Minerva as immune cells get stuck in the fruit fly’s head

Cancers that display a specific combination of sugars, called T-antigen, are more likely to spread through the body and kill a patient. However, what regulates...

Im Focus: The taming of the light screw

DESY and MPSD scientists create high-order harmonics from solids with controlled polarization states, taking advantage of both crystal symmetry and attosecond electronic dynamics. The newly demonstrated technique might find intriguing applications in petahertz electronics and for spectroscopic studies of novel quantum materials.

The nonlinear process of high-order harmonic generation (HHG) in gases is one of the cornerstones of attosecond science (an attosecond is a billionth of a...

Im Focus: Magnetic micro-boats

Nano- and microtechnology are promising candidates not only for medical applications such as drug delivery but also for the creation of little robots or flexible integrated sensors. Scientists from the Max Planck Institute for Polymer Research (MPI-P) have created magnetic microparticles, with a newly developed method, that could pave the way for building micro-motors or guiding drugs in the human body to a target, like a tumor. The preparation of such structures as well as their remote-control can be regulated using magnetic fields and therefore can find application in an array of domains.

The magnetic properties of a material control how this material responds to the presence of a magnetic field. Iron oxide is the main component of rust but also...

Im Focus: Self-healing coating made of corn starch makes small scratches disappear through heat

Due to the special arrangement of its molecules, a new coating made of corn starch is able to repair small scratches by itself through heat: The cross-linking via ring-shaped molecules makes the material mobile, so that it compensates for the scratches and these disappear again.

Superficial micro-scratches on the car body or on other high-gloss surfaces are harmless, but annoying. Especially in the luxury segment such surfaces are...

Im Focus: Stellar cartography

The Potsdam Echelle Polarimetric and Spectroscopic Instrument (PEPSI) at the Large Binocular Telescope (LBT) in Arizona released its first image of the surface magnetic field of another star. In a paper in the European journal Astronomy & Astrophysics, the PEPSI team presents a Zeeman- Doppler-Image of the surface of the magnetically active star II Pegasi.

A special technique allows astronomers to resolve the surfaces of faraway stars. Those are otherwise only seen as point sources, even in the largest telescopes...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

International Modelica Conference with 330 visitors from 21 countries at OTH Regensburg

11.03.2019 | Event News

Selection Completed: 580 Young Scientists from 88 Countries at the Lindau Nobel Laureate Meeting

01.03.2019 | Event News

LightMAT 2019 – 3rd International Conference on Light Materials – Science and Technology

28.02.2019 | Event News

 
Latest News

Searching for disappeared anti-matter: A successful start to measurements with Belle II

26.03.2019 | Physics and Astronomy

Extremely accurate measurements of atom states for quantum computing

26.03.2019 | Physics and Astronomy

Listening to the quantum vacuum

26.03.2019 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>