In recent years, researchers have thought that beta blockers, which are prescribed to many older adults for high blood pressure and heart conditions, might be linked with a decreased risk of cancer. This theory stems from animal and laboratory studies that found that the stress hormone norepinephrine can promote the growth and spread of cancer cells. Beta blockers inhibit norepinephrine's action, so it stands to reason that the medications could have anticancer properties.
Previous studies on beta blockers' effects on colorectal cancer risk have yielded inconsistent results. To provide more thorough information, Michael Hoffmeister, PhD, of the German Cancer Research Center, in Heidelberg, Germany, and his colleagues conducted personal interviews from 2003 to 2007 with 1,762 patients with colorectal cancer and 1,708 cancer-free individuals.
After taking into consideration certain patient characteristics (such as weight and smoking status) and other factors that might influence the results, the researchers found no link between beta blocker use and colorectal cancer risk. Previous studies had not taken these factors into consideration. Even when the investigators broke down their analyses by duration of use of beta blockers, specific types of beta blockers, active ingredients (metoprolol, bisoprolol, carvedilol, and atenolol), and sites within the colon or rectum where colorectal cancer developed, there was no link.
Overall, the results of this study do not support the hypothesis that using beta blockers can lower one's colorectal cancer risk. The findings also point to the importance of considering patient characteristics and other factors that might influence the results of studies that look at how medications affect patients' cancer risk.
Amy Molnar | EurekAlert!
Study relating to materials testing Detecting damages in non-magnetic steel through magnetism
23.07.2018 | Technische Universität Kaiserslautern
Innovative genetic tests for children with developmental disorders and epilepsy
11.07.2018 | Christian-Albrechts-Universität zu Kiel
There are currently great hopes for solid-state batteries. They contain no liquid parts that could leak or catch fire. For this reason, they do not require cooling and are considered to be much safer, more reliable, and longer lasting than traditional lithium-ion batteries. Jülich scientists have now introduced a new concept that allows currents up to ten times greater during charging and discharging than previously described in the literature. The improvement was achieved by a “clever” choice of materials with a focus on consistently good compatibility. All components were made from phosphate compounds, which are well matched both chemically and mechanically.
The low current is considered one of the biggest hurdles in the development of solid-state batteries. It is the reason why the batteries take a relatively long...
New design tool automatically creates nanostructure 3D-print templates for user-given colors
Scientists present work at prestigious SIGGRAPH conference
Most of the objects we see are colored by pigments, but using pigments has disadvantages: such colors can fade, industrial pigments are often toxic, and...
Scientists at the University of California, Los Angeles present new research on a curious cosmic phenomenon known as "whistlers" -- very low frequency packets...
Scientists develop first tool to use machine learning methods to compute flow around interactively designable 3D objects. Tool will be presented at this year’s prestigious SIGGRAPH conference.
When engineers or designers want to test the aerodynamic properties of the newly designed shape of a car, airplane, or other object, they would normally model...
Researchers from TU Graz and their industry partners have unveiled a world first: the prototype of a robot-controlled, high-speed combined charging system (CCS) for electric vehicles that enables series charging of cars in various parking positions.
Global demand for electric vehicles is forecast to rise sharply: by 2025, the number of new vehicle registrations is expected to reach 25 million per year....
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