Scientists have long known that mosquitoes can detect octenol, but this most recent finding by ARS entomologists Joseph Dickens and Jonathan Bohbot explains in greater detail how Ae. aegypti--and possibly other mosquito species--accomplish this.
Dickens and Bohbot, at the ARS Invasive Insect Biocontrol and Behavior Laboratory in Beltsville, Md., have shown that Ae. aegypti taps into the "right-handed" and "left-handed" structural nature of octenol, which is emitted by people, cattle and other mammals. This ability to detect the "handedness" of molecules has been shown in mammals, but the discovery is the first case of scientists finding out how it works in an insect, according to the researchers.
When they hunt for a blood meal, mosquitoes hone in on a variety of chemicals, including carbon dioxide, lactic acid, ammonia and octenol. Octenol is one of many carbon-based compounds that have a molecular structure that can take on either a "right-handed" or "left-handed" form. Each form is a mirror image of the other, and a form's "handedness" is determined by how its molecular bonds are assembled.
The scientists used frog eggs to help them make their discovery. They injected RNA from Ae. aegypti into the frog eggs, allowing the egg membranes to mimic the mosquito's ability to detect octenol. Then they attached microelectrodes to the frog egg cell membranes, passed octenol over them and recorded the electrical signals stimulated by the odors.
They ran the tests using both the right- and left-handed forms of octenol. The scientists found heightened electrical activity when the membrane was exposed to the right-handed form, and weakened activity when it was exposed to the left-handed form.
There are many natural compounds that can take on either a right-handed or left-handed form. While the effects of those differences on many plants and animals remains a mystery, the report, published in PLoS ONE, shows the effects of octenol's dual structure on the yellow fever mosquito and adds to scientists' understanding of how mosquitoes sense the world around them. It also may open the door to speedier development of better mosquito repellents and traps, according to Dickens.
The team's research is being funded by the Department of Defense Deployed War Fighter Protection Research Program.
ARS is the principal intramural scientific research agency of the U.S. Department of Agriculture.
USDA is an equal opportunity provider, employer and lender. To file a complaint of discrimination, write: USDA, Director, Office of Civil Rights, 1400 Independence Ave., S.W., Washington, D.C. 20250-9410 or call (800) 795-3272 (voice), or (202) 720-6382 (TDD).
Dennis O'Brien | EurekAlert!
Researchers simplify tiny structures' construction drip by drip
12.11.2018 | Princeton University, Engineering School
Mandibular movement monitoring may help improve oral sleep apnea devices
06.11.2018 | Elsevier
Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.
Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...
Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.
In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...
On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.
When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure
Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...
Physicists at ETH Zurich demonstrate how errors that occur during the manipulation of quantum system can be monitored and corrected on the fly
The field of quantum computation has seen tremendous progress in recent years. Bit by bit, quantum devices start to challenge conventional computers, at least...
09.11.2018 | Event News
06.11.2018 | Event News
23.10.2018 | Event News
13.11.2018 | Life Sciences
13.11.2018 | Life Sciences
13.11.2018 | Awards Funding