Popular alternative therapy for psoriasis performs no better than placebo

Researchers at the University of Pennsylvania School of Medicine found that despite strong scientific evidence in the laboratory demonstrating the ability of curcumin (the active ingredient in the spice turmeric) to inhibit a critical pathway of psoriasis, the positive response in patients was so low that scientists suggest the placebo effect or the disease’s natural remission might be the reason. The study was published in the Journal of the American Academy of Dermatology.

“Alternative and complementary websites and newspapers publish anecdotal reports that the Indian spice has been successfully used to treat psoriasis,” says Joel M. Gelfand, MD, MSCE, of The University of Pennsylvania School of Medicine. “However, spontaneous improvements in psoriasis are common, and based on our study, until larger, placebo-controlled trials are conducted, oral curcumin should not be recommended for the treatment of psoriasis given lack of proven efficacy.”

But the researchers do not discount entirely the potential of curmumin as a treatment for psoriasis.

They recognize that current traditional pharmacologic approaches in the treatment of psoriasis are costly and have their limitations, including the risk of infections and possibly malignancies with long-term use resulting in many patients with the disease unable to achieve effective long-term control. Turning to complementary and alternative therapies is understandable, they say. In fact, of the estimated 7 million diagnosed with psoriasis, it is estimated that 51% use complementary and alternative medicine therapies to treat their skin.

The excellent responses that were observed in two of the 12 patients in the study suggest that curcumin may have promise for a small subset of patients with psoriasis. Large, placebo-controlled trials are necessary to definitively prove or disprove oral curcumin as a potential therapeutic agent for psoriasis. “What is needed is scientific data to assess the safety and efficacy of these treatments so that we may more rationally inform patients of their treatment options,” says Gelfand.

Media Contact

Marc Kaplan EurekAlert!

Weitere Informationen:

http://www.uphs.upenn.edu

Alle Nachrichten aus der Kategorie: Health and Medicine

This subject area encompasses research and studies in the field of human medicine.

Among the wide-ranging list of topics covered here are anesthesiology, anatomy, surgery, human genetics, hygiene and environmental medicine, internal medicine, neurology, pharmacology, physiology, urology and dental medicine.

Zurück zur Startseite

Kommentare (0)

Schreib Kommentar

Neueste Beiträge

Scientists achieve higher precision weak force measurement between protons, neutrons

Through a one-of-a-kind experiment at the Department of Energy’s Oak Ridge National Laboratory, nuclear physicists have precisely measured the weak interaction between protons and neutrons. The result quantifies the weak…

High-performance single-atom catalysts for high-temperature fuel cells

Individual Pt atoms participate in catalytic reaction to faciitate the electrode process by up to 10 times. Single-atom Pt catalysts are stable at 700 degrees Celsius and expected to stimulate…

New method allows precise gene control by light

A novel optical switch makes it possible to precisely control the lifespan of genetic “copies”. These are used by the cell as building instructions for the production of proteins. The…

By continuing to use the site, you agree to the use of cookies. more information

The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this.

Close