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Parenteral controlled drug delivery is of crucial importance for the pharmacotherapy of many diseases (e.g. breast and prostate cancer, local inflammation). By means of controlled release systems it is possible to decrease the frequency of administration (from hours to months), to increase drug efficiency and to decrease side effects. Direct Injectable OleoGels (DIOGs) and In Situ Forming OleoGels (ISFOGs) were developed as new, biodegradable and lipid based formulations for parenteral controlled release applications. Both formulations have many advantages in terms of manufacturability, rheological properties and release control compared to the currently used drug delivery systems.
Yellow mosaic virus disease leads to substantial losses - up to 50 % of the yield - in susceptible barley varieties (Hordeum vulgare). The disease is caused by different strains of Barley yellow mosaic virus (BaYMV) and Barley mild mosaic virus (BaMMV). It cannot be cured by chemical treatment. The present invention provides a new recessive resistance gene. Variants of the gene lead to resistance against all agents known to cause yellow mosaic virus disease in Europe.
The Technology provides a new and outstanding method for the enhancement of the
quality of dim images. Inspired by the spatial integration of visual information in
nocturnal insects, the algorithm successfully enhances the contrast and brightness of
dim images and removes noise while preserving fine details and object contours. The
patented system is applicable to field programmable gate arrays (FPGA) or image
processors, which offer parallel computing capabilities. A wide variety of capabilities
and markets from automotive sector to the enhancement of diagnostic images can be
Researchers from the University of Oldenburg, Germany, developed a laser cantilever anemometer (LCA) which utilizes the laser pointer principle of a scanning-force microscope to capture the velocity and the angle of fluid flows.
The Carl von Ossietzky University in Oldenburg, Germany, developed a method which markedly improved the quantitative determination of hydrogen. A so-called TPR is conducted by coupling a flame ionization detector (FID) to a methanizer. Adding a certain amount of carbon monoxide (CO) and an excess amount of hydrogen immediately upstream of the FID, CO will react with hydrogen to yield methane. Methane produces a FID signal which is proportional to the amount of hydrogen in the sample.
As yet there has been no satisfactory and easy method to determine the concentrations of substances dissolved in liquid product flows. Previous methods using sensors were not sufficiently reliable and not designed for flow-through systems. Or they required that the analyte whose concentration was to be determined was already known. The device according to invention makes it easy to determine the analyte in a liquid phase both qualitatively and quantitatively.
The Carl von Ossietzky University in Oldenburg, Germany, developed a method which serves the purpose of identifying and quantifying substances (proteins, amino acids, drug constituents) in solution.
Researchers at the University of Oldenburg have developed a flap for wind turbine generators which is mounted parallel to the main rotor blade and is considerably smaller in its size and mass than the main blade. The core piece of the invention is the adjustable pitch of the flap. The flap's pitch as well as its distance to the main blade can be swiftly adjusted to actual wind variations by means of a control unit or adaptive mechanics, thus assuring an optimal airflow at the site of the main rotor. The flap adjustment unit is able to consider the position of the main blade, the actual rotor rotation speed, and the actual wind speed. A purely mechanical adaptive pitch adjustment is also in a state of planning.
The newly developed method improves the monitoring and control process for beam welding. In contrast to most
commonly used methods, the new monitoring process is root sided, i. e. it takes place on the back part of the
workpiece. Furthermore, the invention describes a monitoring device optimized for beam welding. Beam welding
using the invention avoids incomplete fusion at the weld interface and increases the stability of the weld joint.
Method for reducing cross-talk / interference: The optimal utilization of the available frequency bands plays an important role in the transmission of messages. In frequency multiplexing, sub-frequency bands are allocated to individual communication channels, which are usually completely independent of each other. In practice, however, there is cross-talk, that is, in a channel, signals from the two adjacent channels are also received. Thus, the received signal is composed of useful signal and interference signal. The aim of the present invention is to compensate for the interfering signal component. This is particularly important when the intensity of the adjacent channel signals and thus the interference signal which they contribute are greater than the actual useful signal (adjacent channel interference problem).
Charge flow frequency converters are used when especially small electrical currents must be measured. Usually, the integrator and the comparator are connected in series. The improved method can be used anywhere where very small currents of both polarities with high dynamics are measured.
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Die letzten 5 Focus-News des innovations-reports im Überblick:
New technology could allow an MRI contrast agent to 'blink off,' helping doctors diagnose disease
Magnetic resonance imaging, or MRI, is a widely used medical tool for taking pictures of the insides of our body. One way to make MRI scans easier to read is...
At the Hannover Messe 2018, the Bundesanstalt für Materialforschung und-prüfung (BAM) will show how, in the future, astronauts could produce their own tools or spare parts in zero gravity using 3D printing. This will reduce, weight and transport costs for space missions. Visitors can experience the innovative additive manufacturing process live at the fair.
Powder-based additive manufacturing in zero gravity is the name of the project in which a component is produced by applying metallic powder layers and then...
Physicists at the Laboratory for Attosecond Physics, which is jointly run by Ludwig-Maximilians-Universität and the Max Planck Institute of Quantum Optics, have developed a high-power laser system that generates ultrashort pulses of light covering a large share of the mid-infrared spectrum. The researchers envisage a wide range of applications for the technology – in the early diagnosis of cancer, for instance.
Molecules are the building blocks of life. Like all other organisms, we are made of them. They control our biorhythm, and they can also reflect our state of...
University of Connecticut researchers have created a biodegradable composite made of silk fibers that can be used to repair broken load-bearing bones without the complications sometimes presented by other materials.
Repairing major load-bearing bones such as those in the leg can be a long and uncomfortable process.
Study published in the journal ACS Applied Materials & Interfaces is the outcome of an international effort that included teams from Dresden and Berlin in Germany, and the US.
Scientists at the Helmholtz-Zentrum Dresden-Rossendorf (HZDR) together with colleagues from the Helmholtz-Zentrum Berlin (HZB) and the University of Virginia...