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An der Hochschule für Technik und Wirtschaft des Saarlandes (HTW Saar) wurde nun ein System entwickelt, dass die Möglichkeiten erdgedeckter Flüssiggas-tanks optimal aus nutzt und so eine substanzielle Energie-und Kosteneinsparung generiert. Die entscheidende Innovation besteht darin, dass flüssiggas betriebene Blockheizkraftwerk (BHKW) mit einer Wärmepumpe zu koppeln, wobei der Gastank außer zur Speicherung des Flüssiggases gleichzeitig als Erdwärmekollektor und Verdampfer für die Wärmepumpe genutzt wird. Dies ist nur bei einem erdgedeckten Tank sinnvoll möglich. Das Flüssiggas dient im laufenden Betrieb gleichzeitig als Kraftstoff und als Kältemittel. Die erfindungsgemäße Anlage trägt auf diese Weise dazu bei, Betriebskosten zu reduzieren und die Energieeffizienz des Systems zu steigern. Da die verwendeten Komponenten bis auf wenige Bauteile mit denen eines herkömmlichen flüssiggasbetriebenen BHKW übereinstimmen, kann auf einfache Weise und ohne die Anschaffung separater Wärmekollektoren ein deutliches Einsparpotenzial nutzbar gemacht werden. Modellrechnungen ergeben eine Reduktion des Kraftstoffverbrauchs von bis zu 40%. Die Optimierung des gesamten Systems im Hinblick auf die verschieden Betriebsparameter ist Gegenstand einer aktuellen Prototypenstudie. 15.04.2015 | nachricht Read more

Biosensor and method to analyze specific components of complex fluids

The presented method combines the advantages of a highly specific and sensitive immunological sensor surface with the extensive detail of an infrared spectroscopic analysis, with particular regard to the secondary structure analysis of protein biomarker candidates. Every non-clotting, cell-free fluid is analyzable. 14.04.2015 | nachricht Read more

Force constant adaptation of braided sleeving in the automated production of braided components

The Institute of Aircraft Design (IFB) at the University of Stuttgart developed a flexible pressure roll mechanism for braiding machines, which significantly improves the automated braiding of components with sharp curvatures and widely varying cross-sections without the need for manual intervention. While overbraiding a mandrel the flexible mounting of the pressure rolls allows for adaptation to the mandrel's positioning (e.g. inclined position) and to changes in the cross section. They exert a constant and precisely defined force on the braid and thereby press it against the mandrel. As part of the automated process, the robot control of the braiding machine coordinates the movement of the pressure rolls. This significantly improves the braiding of components with a variable cross-section and curvatures so that manual intervention is no longer required. 01.04.2015 | nachricht Read more

Ultrasonic sensor with adjustable protective cover for the dental approximal region

Based on a very thin, high-strength design of the invention the ultrasonic sensor is placed between the teeth of the approximal region, thus reducing the distance significantly. As a result the images posses a very high spatial resolution. The ultrasonic sensor consists of a metallic base plate with a reinforced frame, made of high-strength pure titanium or a TiAl6V4 alloy. The edges of the frame are rounded to make the insertion in the approximal region more comfortable. The total thickness of the design is limited to a maximum of 0.8 mm. The piezoelectric part is made on a PVDF-film equipped with spacers and shielded by an adjustable cover. The cover allows for a special contact by respecting the safety clearance to the teeth. By removing the cover hydrogel is pumped into the gap to provide acoustic coupling. In addition, it is used for lubrication of the cover movement. 31.03.2015 | nachricht Read more

PEN - Efficient and catalytic formation of highly substituted Pyrazoles by Enamines and Nitriles

Scientist at the Westfälische Wilhelms University of Münster developed the efficient Cu-catalyzed PEN method for the formation of tetra-substituted pyrazoles. In this atomeconomic process, readily available enamines and nitriles are reacted by C-C and N-N bond formation. A broad scope of enamines and nitriles can be utilized in this process. 30.03.2015 | nachricht Read more

Low-vibration sample holder for cryo fluorescence microscopic applications

The invention relates to a sample holder to be used in cryo fluorescence microscopes or to simply and cost effectively upgrade a room temperature fluorescence microscope. The holder solves existing problems regarding thermal and mechanical stability of the sample and allows for a localization accuracy of a few hundred Angstroms. 27.03.2015 | nachricht Read more

Variable number of threads in braiding machines

A new embodiment of a braiding machine was developed at the Institute of Aircraft Design (IFB) of Stuttgart University. It features a thread positioning unit which forms a secondary ring of horn-gears close to the braiding point. This secondary ring moves synchronously with the primary horn-gears of the braiding machine. Therefore, the position of each thread, that is close to the mandrel, is clearly defined. This is a basic requirement for manipulation of specific threads during the braiding process, which in turn permits the automated production of components with highly varying diameters at a constant braid angle. 16.03.2015 | nachricht Read more

Modulators of sphingolipid signaling for the treatment of multiple sclerosis

The agonistic prodrug Fingolimod (FTY720) en-abled the first oral treatment of relapsing-remitting multiple sclerosis by modulating sphin-golipid signaling. Scientists developed novel Fingolimod non-prodrug derivatives, which re-duce the blood-brain-barrier leakage and blood T lymphocytes. Advantageously one derivative is fully active in the absence of sphingosine ki-nase 2 while exhibiting comparable activity to Fingolimod. 13.03.2015 | nachricht Read more

Point-of-care monitoring of blood coagulation time via 'Surface Acoustic Waves' (SAW)

Scientists from Goethe University Frankfurt developed a new mobile device to determine ad-hoc coagulation times from full-blood samples utilizing "surface acoustic waves". This coagulation time is of high importance e.g. during emergency situations when the coagulation status of a patient under anticoagulant therapy needs rapid evaluation. 13.03.2015 | nachricht Read more

Moguntinones – a novel class of kinase inhibitors for cancer therapy

Moguntinones, a class of small molecule compounds comprise 3-(indolyl)- or 3-(azaindolyl)-4-arylmaleimide derivatives with tumor and vascular targeting properties. The present invention relates to the use of Moguntinones for treatment of colorectal or gastric adenocarcinoma. Tumor growth and metastasis are highly associated with the overexpression of protein kinases. Therefore protein kinases are an interesting class of target molecules for improved therapeutic attempts. These proteins are known to regulate the majority of cellular pathways including such relevant for control cell growth, movement and death - all processes relevant for cancer growth and progression. A physiological process focused on in development of anti-cancer agents is apoptosis, a controlled form of cell death eliminating damaged, aberrant, infected, old or superfluous cells. In particular often mucosa tissue such as gastrointestinal mucosa is characterized by a rapid epithelial cell turnover in which homeostasis is maintained predominantly by apoptosis. One essential prerequisite for growth and metastasis of cancers which form tumors is angiogenesis, a process involving the formation of new blood vessels from pre-existing capillary endothelial cells. Tumor cells may enhance angiogenesis by overexpression of proangiogenic factors, e.g. VEGF or interleukins. In general, this is especially pronounced with tumors having a high microvessel density as well as a particular aggressive behavior and high tendency to metastasize. Therefore, inhibitors of angiogenesis are researched as antitumor agents. [Ref. UMZ252] 12.03.2015 | nachricht Read more
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Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Advances in Molecular Electronics: Lights On – Molecule On

Scientists at the Helmholtz-Zentrum Dresden-Rossendorf (HZDR) and the University of Konstanz are working on storing and processing information on the level of single molecules to create the smallest possible components that will combine autonomously to form a circuit. As recently reported in the academic journal Advanced Science, the researchers can switch on the current flow through a single molecule for the first time with the help of light.

Dr. Artur Erbe, physicist at the HZDR, is convinced that in the future molecular electronics will open the door for novel and increasingly smaller – while also...

Im Focus: Pruning of Blood Vessels: Cells Can Fuse With Themselves

Cells of the vascular system of vertebrates can fuse with themselves. This process, which occurs when a blood vessel is no longer necessary and pruned, has now been described on the cellular level by Prof. Markus Affolter from the Biozentrum of the University of Basel. The findings of this study have been published in the journal “PLoS Biology”.

The vascular system is the supply network of the human organism and delivers oxygen and nutrients to the last corners of the body. So far, research on the...

Im Focus: Astronomers reveal supermassive black hole's intense magnetic field

Astronomers from Chalmers University of Technology have used the giant telescope Alma to reveal an extremely powerful magnetic field very close to a supermassive black hole in a distant galaxy

Astronomers from Chalmers University of Technology have used the giant telescope Alma to reveal an extremely powerful magnetic field very close to a...

Im Focus: A “pin ball machine” for atoms and photons

A team of physicists from MPQ, Caltech, and ICFO proposes the combination of nano-photonics with ultracold atoms for simulating quantum many-body systems and creating new states of matter.

Ultracold atoms in the so-called optical lattices, that are generated by crosswise superposition of laser beams, have been proven to be one of the most...

Im Focus: UV light robot to clean hospital rooms could help stop spread of 'superbugs'

Can a robot clean a hospital room just as well as a person?

According to new research out of the Texas A&M Health Science Center College of Medicine, that is indeed the case. Chetan Jinadatha, M.D., M.P.H., assistant...

All Focus news of the innovation-report >>>



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