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The newly developed method aims at producing small gratings on different materials, especially on glass surfaces, by ablating small amounts of material. The gratings can be small enough to form patterns with a diffractive effect causing the material to schiller in different colors.
Immunization is an important tool to fight diseases caused by viral, bacterial or fungal pathogenes. The invention provides a new approach for the generation of oligomeric vaccines. The underlying principle is the high affinity interaction between S-protein and a modified S-tag of bovine pancreatic RNase A which is applied to hemagglutinin (H5). The technology can be applied to produce high molecular vaccines. They have many advantages compared to recently used vaccines including high immunogenicity, high stability, short production time and lower production costs. The approach could therefore be used for the immunization of livestock.
Traditional battery materials, e. g. for Li-ion batteries are brittle, thus not suitable for high capacity flexible batteries. Rigid organic redox polymer batteries have low volumetric energy and power density.
Using a new colloid consisting, of redox pol-ymer and graphene oxide that is trans-formed into reduced graphene oxide during preparation, thickness scalable cathodic and anodic battery materials reaching 1.3 mAh/cm2 for flexible and at least 21 mAh/cm2 for rigid materials are available. The new technologa offers the following advantages:
higher capacities materials for flexible batteries,
scalability 1 20 mAh/cm2,
tailord redox-potential and
"Q-primers" are ammonium compounds, which make it possible to permanently functionalize virtually any surface. It is an environmentally friendly and cost-effective process that allows the production of ultra-thin layers and an "on demand" functionalization. The carrier quat primer can be equipped with any functional groups so that an universally applicable strategy for the modification of surfaces is now available.
This innovative carbonization process of carbon precursor fibers creates in a fast and energy saving manner carbon fibers (CF) which are highly porous (small pore diameters from 0.1 to 10 nm) and have a high surface area (100 to 2500 m2/g). The pyrolysis step needs only minutes or even seconds.
No additional additives like pore-providing templates, catalytic compounds or corrosive liquids are required. However, filler materials like pigments, dyes, graphene nanoplatelets or metal- and semiconductor nanoparticles can be admixed to vary the performance of the produced carbon fibers, e.g. to increase electrical conductivity. Overall, this technology combines conventional carbonization and activation treatments into one process and is more economical by saving time, costs and resources compared to already known thermal carbonization methods.
Applications of carbon fibers are known in the art. Electric applications like super caps and electrodes or filtration and adsorption for gas, water and solvent purification might be preferable.
A herbal remedy is effective against the Ebola virus. The natural compound silvestrol reduces the number of pathogens in infected cells. Also the production of virulent proteins is largely suppressed if the natural substance is used.
Parenteral controlled drug delivery is of crucial importance for the pharmacotherapy of many diseases (e.g. breast and prostate cancer, local inflammation). By means of controlled release systems it is possible to decrease the frequency of administration (from hours to months), to increase drug efficiency and to decrease side effects. The problem is solved by providing Direct Injectable Polymer Solutions (DIPOs) which act as a depot after administration. Their polarity and degradation rate is adjustable. They are much less acidic compared to PLA/PLGA polymers.
Dendrimers are spherical, highly branched polymers used in the fields of drug delivery and drug targeting, DNA/RNA delivery, imaging, protein labelling, protein crosslinking and protein separation, coagulation inhibition, and surface, cell and tissue recognition. They are also used as macroamphiphiles and catalyst supports. All previously existing dendrimers require special, branched and partially protected or polyreactive building blocks for their synthesis. A disadvantage is the limited range of dendrimers with varying structures that can be produced, and the concentration to few dendron forming functional groups.
The new technology offers the possibility of synthesising dendrimers with almost any combination of branch lengths, degree of branching, internal and terminal groups. This is achieved by means of multiple iterative multicomponent reactions, e.g. with acidic, alkaline, hydrophilic, lipophilic, sugar and other functional groups.
DNA assembly methods such as such as Gibson and Golden Gate cloning are basic tools for synthetic biology. Both methods allow assembly of constructs from multiple DNA fragments in a one-pot one-step assembly reaction. Standardization of parts is another essential element of modern synthetic biology. A novel method has been developed to assemble constructs from several individual DNA parts - each kept on a solid carrier - directly in a one-pot one-step reaction.
Parenteral controlled drug delivery is of crucial importance for the pharmacotherapy of many diseases (e.g. breast and prostate cancer, local inflammation). By means of controlled release systems it is possible to decrease the frequency of administration (from hours to months), to increase drug efficiency and to decrease side effects. Direct Injectable OleoGels (DIOGs) and In Situ Forming OleoGels (ISFOGs) were developed as new, biodegradable and lipid based formulations for parenteral controlled release applications. Both formulations have many advantages in terms of manufacturability, rheological properties and release control compared to the currently used drug delivery systems.
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Die letzten 5 Focus-News des innovations-reports im Überblick:
The Institute of Semiconductor Technology and the Institute of Physical and Theoretical Chemistry, both members of the Laboratory for Emerging Nanometrology (LENA), at Technische Universität Braunschweig are partners in a new European research project entitled ChipScope, which aims to develop a completely new and extremely small optical microscope capable of observing the interior of living cells in real time. A consortium of 7 partners from 5 countries will tackle this issue with very ambitious objectives during a four-year research program.
To demonstrate the usefulness of this new scientific tool, at the end of the project the developed chip-sized microscope will be used to observe in real-time...
Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.
The results will be published on March 22 in the journal „Astronomy & Astrophysics“.
Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...
Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.
Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...
Layered 2D material improves efficiency for solar cells and LEDs
In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...