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Plasma device for tapes and other flexible materials

Surface activation or cleaning by cold plasma is getting more and more attention. Current plasma-based solutions for flexible materials however lack efficiency or are technically too complex and error-prone. Scientists at the HAWK developed a plasma roller device for effective and fast plasma treatment of flexible materials. 03.09.2015 | nachricht Read more

1,2-difunctionalized Diamondoids - New Class of Substances

The adamantane moiety is a very versatile chemical core-structure. It is e.g. incorporated in medically active compounds like Vildagliptin®, a remedy against diabetes. The innovation presented here provides a new and straightforward way for synthesizing this new class of 1,2-substituted dia-mondoids, which can well be used as intermediate starting ma-terials for further chemical synthesis. 03.09.2015 | nachricht Read more

Improved CAR T-cells - Bispecific chimeric antigen receptors with a CD30 binding domain

Adoptive T-cell therapy is a very promising approach in the treatment of cancer. Early phase clinical trials with genetically engineered T-cells expressing a tumor-specific chimeric antigen receptor (CAR) show significant efficacy in the treatment. However, currently used CAR modified T-cells for antigen-directed targeting towards tumor cells have insufficient performance in the anti-tumor attack, e. g. less amplification and cytolytic activity after the transfer of the modified T-cells into the patient. Scientists from the University Medical Center of Cologne developed a bispecific CAR, which improves the performance of genetically engineered T-cells expressing these CAR polypeptides on their surface. The bispecific CAR comprises two antibody units, with one antibody unit being an anti-CD30 single chain antibody unit and the other antibody unit being an antibody unit specific for an antigen present on the surface of a predetermined target cell, e. g. for the tumor carcino-embryonic antigen (CEA) on breast cancer cells. 02.09.2015 | nachricht Read more

Anti CD30 CAR - Anti CD30 chimeric antigen receptor selectively targets tumor cells

The invention describes a CAR which recognizes CD30 as a target antigen and initiates lysis of CD30-positive (CD30+) tumor cells but not of CD30+ healthy cells like hematopoietic stem cells. Specific genetic modifications of the anti-CD30 CAR ensure the specific targeting of CD30+ tumor cells and prevent unwanted side-effects. This approach has been tested in vitro with CD30+ hematopoietic stem cells and CD30+ tumor cells and in vivo in mice transplanted with human CD30+ hematopoietic stem cells. In vivo experiments provided evidence that the treatment with anti-CD30 T-cells has no unwanted impact on the endogenous immune system. Thus, the CAR is most suitable for clinical application in targeting CD30+ leukemia and lymphoma cells. A clinical study phase I is planned for early 2016, indication: cutaneous T-cell lymphoma. 02.09.2015 | nachricht Read more

FES-ChemSensor - Gassensoren auf Basis der PEO-Technologie

Auf Grundlage eines neuen Oxidationsverfahrens wurden Gassensoren entwickelt, die ohne die sonst notwendige Sensorheizung auskommen. Das besondere Verfahren der potentiostatisch und galvanostatisch kontrollierten plasma-elektrolytischen Oxidation (PEO) ermöglicht dabei die Herstellung einer mechanisch stabilen TiO2-Schicht mit exzellenter Adhäsion auf einer Titanfolie. 01.09.2015 | nachricht Read more

Specific coating of surfaces by enzymes

Biological coatings have a high potential for manifold applications, especially for medical applications or biodegradable coatings. Up to now, the formation of biological coatings is accompanied either by a low control over film formation or connected to high costs. Current challenges that need to be overcome are a high control over the film thickness, an even and continuous coating of objects with a complex geometry, or the site-specific coating of single areas on one object. The new concept Enzymatic Bio-Coating is able to solve these Problems. Suitable supports are: Glass, wood, and miscellaneous plastics and metals. Casein layers are antibacterial, edible, and renewable. 01.09.2015 | nachricht Read more

Method for the specific Diagnosis of Fusarium Infections

This new biomarker provides a convenient and reliable assay for the detection and differentiation of Fusarium from other fungal pathogens, especially Aspergillus. 21.08.2015 | nachricht Read more

Smart chip collector

The radial adjustable suction hood increases the efficiency of the chip waste handling. 21.08.2015 | nachricht Read more

Quality management and security tech-nology based on THz Time Domain Spectroscopy

The THz Time Domain Spectroscopy (THz-TDS) offers unique possibilities to obtain information about the structure and composition of a series of material classes, in particular dielectric materials. This technology can be used as a routine application in inline monitoring in the food, plastics and paper industries, as well as in the security sector. 20.08.2015 | nachricht Read more

STRAP Method for Improved Pitch Perception via Cochlea Implants

Scientists from Goethe University Frankfurt am Main have developed the so-called STRAP (Steering of Tonotopic Rate Adaptive Pitch) procedure for optimizing the stimulation strategy for cochlea implants. By position-dependent adjustment of the stimulation rate to each individual electrode, a much more precise pitch perception is achieved. 19.08.2015 | nachricht Read more
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Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Hubble survey unlocks clues to star birth in neighboring galaxy

In a survey of NASA's Hubble Space Telescope images of 2,753 young, blue star clusters in the neighboring Andromeda galaxy (M31), astronomers have found that M31 and our own galaxy have a similar percentage of newborn stars based on mass.

By nailing down what percentage of stars have a particular mass within a cluster, or the Initial Mass Function (IMF), scientists can better interpret the light...

Im Focus: Fraunhofer ISE Develops Highly Compact Inverter for Uninterruptible Power Supplies

Silicon Carbide Components Enable Efficiency of 98.7 percent

Researchers at the Fraunhofer Institute for Solar Energy Systems ISE have developed a highly compact and efficient inverter for use in uninterruptible power...

Im Focus: How wind sculpted Earth's largest dust deposit

China's Loess Plateau was formed by wind alternately depositing dust or removing dust over the last 2.6 million years, according to a new report from University of Arizona geoscientists. The study is the first to explain how the steep-fronted plateau formed.

China's Loess Plateau was formed by wind alternately depositing dust or removing dust over the last 2.6 million years, according to a new report from...

Im Focus: An engineered surface unsticks sticky water droplets

The leaves of the lotus flower, and other natural surfaces that repel water and dirt, have been the model for many types of engineered liquid-repelling surfaces. As slippery as these surfaces are, however, tiny water droplets still stick to them. Now, Penn State researchers have developed nano/micro-textured, highly slippery surfaces able to outperform these naturally inspired coatings, particularly when the water is a vapor or tiny droplets.

Enhancing the mobility of liquid droplets on rough surfaces could improve condensation heat transfer for power-plant heat exchangers, create more efficient...

Im Focus: Increasingly severe disturbances weaken world's temperate forests

Longer, more severe, and hotter droughts and a myriad of other threats, including diseases and more extensive and severe wildfires, are threatening to transform some of the world's temperate forests, a new study published in Science has found. Without informed management, some forests could convert to shrublands or grasslands within the coming decades.

"While we have been trying to manage for resilience of 20th century conditions, we realize now that we must prepare for transformations and attempt to ease...

All Focus news of the innovation-report >>>



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Together - Work - Experience

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Ion implanted, co-annealed, screen-printed 21% efficient n-PERT solar cells with a bifaciality >97%

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