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Improved ex-vivo expansion of immune cells for use in cell therapy

Researchers from Goethe University Frankfurt developed a new method to increase proliferation and viability of immune cells, e.g. natural killer (NK) cells, derived from patients or donors. The obtained NK cell preparations are currently further evaluated for treatment of leukemia patients. 17.11.2015 | nachricht Read more

Inhibitors of Adipose Triglyceride Lipase (ATGL) for the treatment of Diabetes II and tumour-induced cachexia

The University offers a new technology addressing at least the two markets of tumour-induced cachexia and diabetes type II. Cancer has become a constantly increasing problem and thus about 1 % of all people in highly developed countries are hit by cachexia, leading to approximately 9 million patients for Europe, Japan and the US. Furthermore, diabetes type II is one of the major lifestyle diseases in the modern world. 13.11.2015 | nachricht Read more

New Enzymes for production of aldehydes – Enzymatic alkene cleavage

The University offers an unprecedented enzyme that cleaves alkenes to the corresponding aldehydes at the expense of molecular oxygen. This mild and selective oxidation method has broad applicability either for the preparation of aldehyde intermediated or for the chemical production of aromatic essences and flavourings enabling a reduction of chemical solvents and cheaper production processes. The markets for using this enzyme are the fine chemicals and the aromatic/flavourings industries. 13.11.2015 | nachricht Read more

Joining technology for composite constructions made of metal and fiber-reinforced plastic compounds

This invention describes a new joining procedure for creating hybrid connections between metallic and non-metallic mating components, so called multi-material design. Advantages of this innovation are amongst others the short process times (a few seconds), the preservation of the fibers in the fiber-reinforced compound (no mechanical or thermal destruction) as well as the increase in head tensile strength (vertical stress direction to the component surface through the pin head). 13.11.2015 | nachricht Read more

Phospholipids against American foulbrood and European foulbrood in honeybees

New treatment concept against two devastating honeybee larval diseases, i.e., American and European foulbrood (AFB, EFB), based on the natural compound lysophosphatidylcholine (LPC). LPC exhibits strong antibacterial activity against the causative agents of AFB and EFB and LPC supplementation to honeybee larvae was proven to reduce the outbreak of AFB significantly. The utilization of an LPC based therapy contributes to improve environmental sustainability in honeybee health and may offer new business perspectives in veterinary medicine. 13.11.2015 | nachricht Read more

Access to novel p-hydroxy styrene polymer building blocks

The technology offers a new one-pot reaction to prepare efficiently various aryl substituted p-hydroxy styrene derivatives from phenol derivatives and pyruvic acid as starting materials. The para-vinylated phenols of the enzymatic / biocatalytic reaction can be used as monomers for the production of polymers, likely novel polystyrene or polyphenol derivatives. Properties of the resulting polmyers might offer the use as flame retardant material or in electronic industry. 13.11.2015 | nachricht Read more

Non-destructive energy determination of ion beams

Ion beams are applied in many fields, such as medicine, semiconductor industry and basic research. The invention intoduced here relates to a measurement device and a method to determine the energy of accelerated ions without destructing them. 12.11.2015 | nachricht Read more

Overlap Fix - High performance textile structures for composites through open reed weaving

Inventors of the RWTH Aachen University filed a patent relating the production of the multiaxial enforcement fabrics for textile composites with ORW (Open Reed Weave). To avoid load path interruptions in composites with textile enforcement, an overlapping of two yarn systems in the textile, by means of a special weaving pattern, leads to continuous load path in bias direction, reaching a “Triaxial” fabric, which is the main approach of the investigation. The Angle of additional reinforcement direction is adjustable and the calculated necessary overlapping is 16.28 mm length. The system´s capability was verified by conducting three-point bending tests. These are performed varying the overlapping length, testing carbon and glass fibers and using reference samples as follows: [0/90°] fabrics and [0/90/45°] fabrics with continuous reinforcement. The results were successful in all cases. PROvendis offers licenses for interested enterprises on behalf of the University of Aachen. 11.11.2015 | nachricht Read more

MagnetWeft - Magnetic Weft Insertion in weaving machines

The object of the invention was hence to develop a weaving method of weft insertion that combines the advantages of the common methods whilst avoiding their deficits. This will be achieved with a magnetic projectile which is used for the guided transport of the yarn. The projectile is moved through the open shed by magnets, which are mounted on a belt. The belt is located outside of the shed. Multiple projectiles can be used simultaneously to ensure a high efficiency of the weft insertion. The magnetic weft insertion represents an energy-efficient alternative to the standard weft insertion methods. The fact that production velocities of yarns with challenging processing characteristics can be similar to the ones of standard yarns is certainly an advantage. In magnetic weft insertion no source of compressed air is necessary, a reduction of energy consumption of about 60 % compared to a conventional air jet weaving machine is to be achieved. 11.11.2015 | nachricht Read more

Humanized anti-CCR2 Antibody for the Therapy of MS and RA

Scientists of the University of Göttingen and of the University of Regensburg developed in collaboration a proprietary anti-CCR2 antibodies for the therapy of Multiple Sclerosis (MS) and potentially Rheumatoid Arthritis (RA).The lead candidate Doc-2 has been humanized in collaboration with the MRC Technologies. It targets the CCR2 receptor and modulates the autoimmune process through depletion of CCR2+ monocytes. 11.11.2015 | nachricht Read more
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Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Climate study finds evidence of global shift in the 1980s

Planet Earth experienced a global climate shift in the late 1980s on an unprecedented scale, fuelled by anthropogenic warming and a volcanic eruption, according to new research published this week.

Scientists say that a major step change, or ‘regime shift’, in the Earth’s biophysical systems, from the upper atmosphere to the depths of the ocean and from...

Im Focus: Innovative Photovoltaics – from the Lab to the Façade

Fraunhofer ISE Demonstrates New Cell and Module Technologies on its Outer Building Façade

The Fraunhofer Institute for Solar Energy Systems ISE has installed 70 photovoltaic modules on the outer façade of one of its lab buildings. The modules were...

Im Focus: Lactate for Brain Energy

Nerve cells cover their high energy demand with glucose and lactate. Scientists of the University of Zurich now provide new support for this. They show for the first time in the intact mouse brain evidence for an exchange of lactate between different brain cells. With this study they were able to confirm a 20-year old hypothesis.

In comparison to other organs, the human brain has the highest energy requirements. The supply of energy for nerve cells and the particular role of lactic acid...

Im Focus: Laser process simulation available as app for first time

In laser material processing, the simulation of processes has made great strides over the past few years. Today, the software can predict relatively well what will happen on the workpiece. Unfortunately, it is also highly complex and requires a lot of computing time. Thanks to clever simplification, experts from Fraunhofer ILT are now able to offer the first-ever simulation software that calculates processes in real time and also runs on tablet computers and smartphones. The fast software enables users to do without expensive experiments and to find optimum process parameters even more effectively.

Before now, the reliable simulation of laser processes was a job for experts. Armed with sophisticated software packages and after many hours on computer...

Im Focus: Quantum Simulation: A Better Understanding of Magnetism

Heidelberg physicists use ultracold atoms to imitate the behaviour of electrons in a solid

Researchers at Heidelberg University have devised a new way to study the phenomenon of magnetism. Using ultracold atoms at near absolute zero, they prepared a...

All Focus news of the innovation-report >>>



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