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Bioabbaubare Nano- und Mesopolymerpartikel zum Schutz des pulmonalen Surfactants der Lunge

Bei der Innovation handelt es sich um biokompatible Nano-, Meso- und Mikropolymerpartikel zur Bindung pathogener Proteine, die in den Lining Layer der Lunge eindringen. Die Innovation ermöglicht die Prävention und Behandlung von Lungenerkrankungen, die mit einem Anstieg der Oberflächen-spannung in der Lunge und einer Schädigung des pulmonalen Surfactants einhergehen. 24.05.2016 | nachricht Read more

Durable coating with extracellular matrix for cell culture through bio orthogonal functionalization of a extracellular matrix

During a joint research project scientists at the University of Stuttgart and the University of Konstanz developed an ECM with functional groups (clickECM) which is covalently and thus firmly bonded to surfaces via bioorthogonal ligation reactions. The fixed bonding obtained through the click reaction also ensures that the clickECM coating, e.g. when used for cell culture vessels, withstands extensive washing. The coating is highly stable and can be produced economically without any costly purification or isolation processes. The clickECM only differs from a natural ECM in terms of the introduced functional group. 23.05.2016 | nachricht Read more

Mutation Detection in ctDNA or CTC - Highly sensitive, fast and cost-effective detection of gene modifications and mutations in ctDNA or CTC

Scientists of the University of Duisburg-Essen developed a platform, which facilitates the detection of deletions and insertions as well as point mutations in target genes from a variety of sources against a huge background of wild type alleles, making a clear “Yes” or “No” output possible and thereby simplifying therapeutic decisions. Neither expensive and complicated equipment nor specialized personnel is needed. The assay is robust and applicable in all laboratories equipped with an RT-PCR machine. It can easily be established for point of care (PoC) purposes. This sensitive technology now enables clinicians to be independent of the scarce resource “tissue biopsy”. By using blood (ctDNA, cfDNA or CTC) it opens new non-invasive possibilities for monitoring the mutation status of patients before and during treatment as well as to detect disease relapse early. A European and a US patent have already been granted, other applications are pending. 23.05.2016 | nachricht Read more

Method and device for additive manufacturing of parts out of amorphous or partially crystalline metals by extrusion

Invention is used for additive manufactur-ing of parts out of amorphous or partly crystalline metals with low melting point. This is done with an extrusion method. The used material, metal granulate, is heated up to the glass transition temperature and partly up to the melting temperature. By doing so, the material is moved into a thermoplastic state. After heating, the material can then be extruded by pressure and is selectively placed onto a building platform. The system described in this invention is able to manufacture hollow constructions along with complex parts, all with good mechanical properties. Due to the generating of the part onto the building platform it is not necessary to clean or post process the part as it would be with other methods. 18.05.2016 | nachricht Read more

Miniaturized photovoltaic cells for the study of large-scale neuronal networks in up to three dimensions

Advances in neurosciences are linked to neuron stimulation. Our technology presents the use of Schottky miniaturized photovoltaic cells for this goal, showing remarkable advantages respect stablished techniques, as Patch clamp or Optogenetics. 12.05.2016 | nachricht Read more

Simultaneous production of differently doped areas on a solar cell using borosilicate glass

When producing rear contact solar cells, both negatively and positively doped areas need to be produced on the rear of the solar cell. Moreover, the front side of the solar cell has to be sufficiently passivated in order to minimize surface recombination. This means three differently doped areas are required. Scientists of the University of Konstanz have now developed a new method for producing these three areas in a single diffusion step. This approach is based on the application of a borosilicate glass layer and partial silicon nitride masking on the rear of the solar cell. 09.05.2016 | nachricht Read more

Methylation of JNK commuter enhancer as a marker estimating the risk of a subject for afflictedness with an addiction

The invention discloses methylation patterns found in umbilical cord blood which might be indicative towards an increased risk of afflictedness with an addiction. 02.05.2016 | nachricht Read more

Fast and efficient selection process for CRISPR-based genome editing

The CRISPR technology could be the most im-portant new genetic engineering technique since the beginning of the biotechnology age in the 1970s. It was shown that it’s possible to use CRISPR to rid mice of muscular dystrophy, cure them of a rare liver disease, make human cells immune to HIV, and genetically modify monkeys. In addition there is interest in using CRISPR to gen-erate monkey models of diseases like autism, schizophrenia, Alzheimer’s disease, and bipolar disorder. 02.05.2016 | nachricht Read more

Compact ammonia-water absorption chiller with increased coefficient of performance

Scientists at the University of Stuttgart have developed an absorption chiller that is extremely compact, lightweight and stable in terms of operation, even at low evaporator temperatures and high heat rejection temperatures. Because of its compactness the absorption chiller has lower production costs and requires less refrigerant than conventional absorption chillers. 02.05.2016 | nachricht Read more

New class of inhibitors targeting selectively the autophagic pathway

The invention discloses two chemical compound families derived from tetrahydrotriazine or coumarin selectively targeting the autophagic pathway. 02.05.2016 | nachricht Read more
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Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Worldwide Success of Tyrolean Wastewater Treatment Technology

A biological and energy-efficient process, developed and patented by the University of Innsbruck, converts nitrogen compounds in wastewater treatment facilities into harmless atmospheric nitrogen gas. This innovative technology is now being refined and marketed jointly with the United States’ DC Water and Sewer Authority (DC Water). The largest DEMON®-system in a wastewater treatment plant is currently being built in Washington, DC.

The DEMON®-system was developed and patented by the University of Innsbruck 11 years ago. Today this successful technology has been implemented in about 70...

Im Focus: Computational high-throughput screening finds hard magnets containing less rare earth elements

Permanent magnets are very important for technologies of the future like electromobility and renewable energy, and rare earth elements (REE) are necessary for their manufacture. The Fraunhofer Institute for Mechanics of Materials IWM in Freiburg, Germany, has now succeeded in identifying promising approaches and materials for new permanent magnets through use of an in-house simulation process based on high-throughput screening (HTS). The team was able to improve magnetic properties this way and at the same time replaced REE with elements that are less expensive and readily available. The results were published in the online technical journal “Scientific Reports”.

The starting point for IWM researchers Wolfgang Körner, Georg Krugel, and Christian Elsässer was a neodymium-iron-nitrogen compound based on a type of...

Im Focus: Atomic precision: technologies for the next-but-one generation of microchips

In the Beyond EUV project, the Fraunhofer Institutes for Laser Technology ILT in Aachen and for Applied Optics and Precision Engineering IOF in Jena are developing key technologies for the manufacture of a new generation of microchips using EUV radiation at a wavelength of 6.7 nm. The resulting structures are barely thicker than single atoms, and they make it possible to produce extremely integrated circuits for such items as wearables or mind-controlled prosthetic limbs.

In 1965 Gordon Moore formulated the law that came to be named after him, which states that the complexity of integrated circuits doubles every one to two...

Im Focus: Researchers demonstrate size quantization of Dirac fermions in graphene

Characterization of high-quality material reveals important details relevant to next generation nanoelectronic devices

Quantum mechanics is the field of physics governing the behavior of things on atomic scales, where things work very differently from our everyday world.

Im Focus: Graphene: A quantum of current

When current comes in discrete packages: Viennese scientists unravel the quantum properties of the carbon material graphene

In 2010 the Nobel Prize in physics was awarded for the discovery of the exceptional material graphene, which consists of a single layer of carbon atoms...

All Focus news of the innovation-report >>>

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