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18 matches found for "thalassemia"

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Avoiding Spleen Removal for Cooley's Anemia Sufferers

Preclinical Study Provides Fresh Perspective on Disease, with Potential New Therapeutic OptionsResearchers from Weill Cornell Medical College may have discovered the precise role of a gene in ...

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Scientists discover novel way to remove iron from ferritin

A new study led by Children's Hospital Oakland Research Institute senior scientist, Elizabeth Theil, Ph.D., is the first to suggest that a small protein or heptapeptide (seven amino acids wrapped...

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Penn Researchers Discover Pathway that Eliminates Genetic Defects in Red Blood Cells

> Researchers at the University of Pennsylvania School of Medicine have discovered a unique molecular pathway that detects and selectively eliminates defective messenger RNAs from red blood cells....

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First case of successful ovarian tissue transplantation between two, non-identical sisters

This first case of a successful transplantation of ovarian tissue between two non-identical sisters is reported in the journal Human Reproduction today (Thursday 2 August) [1]. Professor Jacques Donne...

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Scientists reverse evolution

University of Utah scientists have shown how evolution works by reversing the process, reconstructing a 530-million-year-old gene by combining key portions of two modern mouse genes that descended fro...

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Protein’s role in hemoglobin gene silencing identified

Virginia Commonwealth University Massey Cancer Center researchers have identified the role of a protein in hemoglobin gene silencing that may one day be a potential target for the treatment of genetic...

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Birth defects: 8 million annually worldwide

Hidden toll of dying and disabled children; A comprehensive global analysis identifies trends and interventions Every year an estimated 8 million children -- about 6 percent ...

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Two genetic traits giving Africans malaria protection lose effectiveness when they occur together

Scientists thought sickle and thalassemia traits would be potent combination; instead, they cancel each other out Two genetic conditions--sickle cell trait and a mild versio...

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SWI/SNF and erythropoiesis

A research team headed by Dr. Scott Bultman (University of North Carolina) has identified an essential role for the mammalian SWI/SNF chromatin remodeling complex in red blood cell formation. ...

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Researchers show key protein necessary for normal development of red blood cells

Virginia Commonwealth University researchers studying hemoglobin genes, mutations of which play a role in genetic blood disorders like sickle cell anemia and beta-thalassemia, have shown ...

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Kinder, gentler procedure gives superior results for stem cell transplants

An improved stem cell transplant regimen that is well-tolerated and has a high success rate has been developed by researchers at Washington University School of Medicine in St. Louis. Th...

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Researchers find mechanism that may determine early blood cell fate

Remain a hematopoetic stem cell or become a specialized blood cell? Hematopoietic stem cells, the mother of all blood cells, face a fundamental dilemma in their lives. ...

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Study results show promise for development of gene therapy to treat blood diseases

Researchers have developed a promising new approach for gene therapy of inherited blood disorders that may help overcome therapeutically limiting human stem cell gene transfer efficiency. This ...

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Removing Portion of Spleen Effective in Treating Inherited Childhood Anemias

Researchers from Duke University Medical Center and the Medical College of Wisconsin have shown that removing a portion, instead of all, of the spleen, can successfully treat children with a...

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UNC studies target molecular defects implicated in cancer, genetic diseases

In three separate studies, scientists at the University of North Carolina at Chapel Hill School of Medicine have shown that it is possible to correct defective molecular splicing pathways that ...

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