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42 matches found for "tRNA"

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Discovery of regulatory role of key molecule provides further step towards future gene therapy to control disease

The molecule, known as Lysyl-tRNA synthetase (or LysRS in brief) is one of the most ancient molecules in the cell, where it has long been recognized for its contribution in the translation of the info...

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Scripps research scientists observe human neurodegenerative disorder in fruit flies

A team of scientists from The Scripps Research Institute, Katholeike Universiteit Leuven, and the University of Antwerp, Belgium, among other institutions, has created a genetically modified fruit fly...

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Fruit fly steps in to fight human disease

"Now we have the opportunity to unravel the molecular mechanism behind Charcot-Marie-Tooth, as well as to start looking for substances with therapeutic value." The breakthrough is th...

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Genetic switch potential key to new class of antibiotics

Researchers have determined the structure of a key genetic mechanism at work in bacteria, including some that are deadly to humans, in an important step toward the design of a new class of antibiotics...

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The World's First Discovery of genes in jigsaw-like pieces from an archaeon living in hot spring

A new insight into the origin of genesJapanese researchers have announced the world's first discovery of genes in jigsaw-like pieces from an archaeon living in hot spring, which gives new...

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Worm provides clues about preventing damage caused by low-oxygen during stroke, heart attack

They believe the finding could have implications for conditions such as stroke, heart attack and cancer. Sensitivity to low oxygen helps determine how damaging those medical conditions can be. The res...

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A molecular identity crisis - a "Ribozyme without RNA"

This surprising discovery was made during a project supported by the Austrian Science Fund FWF that focussed on the enzyme RNase P. Contrary to accepted scientific theory, the project team from Vienna...

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Scientists have discovered the cause of the hereditary disease PCH

Scientists from Cologne and Amsterdam have discovered the mutations in human genetics, which cause the hereditary disease ponto cerebellar hypoplasia (PCH) of the types 2 and 4.“In the case of...

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Study Reveals Surprising Details Of The Evolution Of Protein Translation

In the study, researchers report that the dual functions of transfer RNA (reading the genetic blueprint for a protein, and adding a specific amino acid to the protein as it is formed) appear to have o...

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Scientists Identify New Role for 'Power Plants' in Human Cells

The gene products, known as tRNAs, assemble amino acids for the production of proteins within mitochondria. If the mitochondrial tRNA genes are defective or missing, and proteins are not manufactured,...

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Researchers Observe Spontaneous 'Ratcheting' Of Single Ribosome Molecules

Their study, published in the journal Molecular Cell, reveals a key mechanism in the interplay of molecules that allows cells to build the proteins needed to sustain life.Cells use a variety o...

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Arable land can have a negative impact on air quality

Fallow agricultural land and steppe-formation processes are evidently capable of having a much greater effect on global air quality than was previously assumed.This is the conclusion drawn by ...

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Researchers discover critical detail of cellular defense against genetic mistakes

The blueprint for the human body is encoded in genes. Gene expression is the process by which those blueprints are converted into proteins that make up the body’s structures and send its signals. When...

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Researchers See History Of Life In The Structure Of Transfer RNA

The study, co-written by Gustavo Caetano-Anollés, a professor of crop sciences, and postdoctoral researcher Feng-Jie Sun, appears March 7 in PLoS Computational Biology. Caetano-Anollés is an affiliate...

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Scientists identify proteins that help bacteria put up a fight

The finding is a step toward development of drug therapies that could target bacterial resistance at its cellular source. Before researchers can design such drugs, they must understand all of the acti...

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