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176 matches found for "synaptic"

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Cognitive dysfunction reversed in mouse model of Down syndrome

The study, published in Science Translational Medicine on November 18, revealed two important new findings about Down's syndrome in a mouse model: 1) there is evidence that synaptic terminals inv...

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Researchers find potential treatment for Huntington's disease

Investigators at Burnham Institute for Medical Research (Burnham), the University of British Columbia's Centre for Molecular Medicine and Therapeutics and the University of California, San Diego ...

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Now Hear This: Scientists Show How Tiny Cells Deliver Big Sound

Now, reporting on rat experiments in the October 22 issue of Nature, a Johns Hopkins team says it has for what is believed to be the first time managed to measure and record the elusive electrical act...

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Study may explain how a well-known epilepsy and pain drug works

The finding may also point to new therapies for brain injury and neuropathic pain.The role of neurons in the brain and nervous system is well known, but astrocytes, a different type of brain c...

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Know who your friends are

There are rules governing which types of connections should be established, although it remains unclear how neurons ‘know’ these rules. “Recognition seems to occur because neurons are always connected...

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Study pinpoints key mechanism in brain development, raising question about use of anti-seizure drug

This discovery, based on experiments in cell culture and in mice, could advance scientists' understanding of how young children's brains develop as well as point to new approaches toward cou...

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1 small step for neurons, 1 giant leap for nerve cell repair

The repair of damaged nerve cells is a major problem in medicine today. A new study by researchers at the Montreal NeurologicaI Institute and Hospital (The Neuro) and McGill University, is a s...

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Computer Model Shows Changes in Brain Mechanisms for Cocaine Addicts

About 2 million Americans currently use cocaine for its temporary side-effects of euphoria, which have contributed to making it one of the most dangerous and addictive drugs in the country. Co...

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MDC Researchers Discover Molecule Responsible for Axonal Branching

Through the ramification of its fiber-like axon, a single neuron can send branches and thus transmit information into several target areas at the same time. In principle, neurobiologists distinguish b...

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Gene called flower missing link in vesicle uptake in neurons

The extra membrane is then captured in a process called endocytosis and recycled to form a new vesicle to enable the next cycle of release. Most important, exocytosis must be tightly coupled with endo...

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Roaming receptors

Changes in the synaptic strength of neurons, effected by repeated neuronal activity, drive important behavioral processes such as learning and memory. Continuous simulation of a neuron, for example, c...

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Sense of attraction

Many olfactory cues pervade the aquatic environment of fish. These cues stimulate various important behaviors, such as escape from predators, or attraction towards food sources or potential mates....

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First Direct Visualization of Memory Formation in the Brain

The phenomenon is called “synaptic plasticity,” and is the foundation for how we learn and remember. As we learn, the memories are stored in changes in the strength and/or number of synaptic connectio...

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Huntington's disease deciphered

The researchers were able to show that the mutated huntingtin gene activates a particular enzyme, called JNK3, which is expressed only in neurons and, further, to show what effect activation of that e...

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Impaired brain plasticity linked to Angelman syndrome learning deficits

Researchers at the University of North Carolina at Chapel Hill School of Medicine and Duke University now believe they have the answer: impaired brain plasticity."When we have experiences...

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