While they are powerful killers of some breast cancer cells, new drugs called histone deacetylase inhibitors, or HDAC inhibitors, also increase self-digestion, or autophagy, in surviving, mega-stresse...
Health and Medicine |Investigators at Burnham Institute for Medical Research (Burnham), the University of British Columbia's Centre for Molecular Medicine and Therapeutics and the University of California, San Diego ...
Health and Medicine |Molecular signal pathways that stimulate the division of stem cells are generally the same as those active in tumour growth. This limits the possibility of treating cancer as the drugs that kill cance...
Health and Medicine |Investigators at Burnham Institute for Medical Research (Burnham) and colleagues have identified a novel mouse gene (Rps23r1) that reduces the accumulation of two toxic proteins that are major players...
Life Sciences |Long-term variations in volcanism help explain the birth, evolution and death of striking geological features called oceanic core complexes on the ocean floor, says geologist Dr Bram Murton of the Nat...
Earth Sciences |The new sensors of the compact series in M30 design have a reduced blind zone and are shorter than models of the previous generation. These improvements make for better detection of objects at close r...
Machine Engineering |The chemical is hydrogen peroxide (H2O2), the active ingredient in color safe bleach. Produced in all animal cells, hydrogen peroxide may act as a signal for the active and resting phases of living th...
Life Sciences |When small earthquakes shake the central U.S., citizens often fear the rumbles are signs a big earthquake is coming. Fortunately, new research instead shows that most of these earthquakes are aftersho...
Earth Sciences |Our breakfast egg is a peculiarity of nature: a single cell protected by a thin mineral layer. Apart from a number of tiny radiolaria and diatoms, individual cells normally do not have a hard shell. ...
Life Sciences |"Therapy with EBV-specific CTLs (cytotoxic lymphocytes) was effective for these patients who were severely immune-compromised, as the cells successfully reached the tumor, multiplied and were abl...
Health and Medicine |One of the best ways to watch the complex workings of living cells is to label components, such as DNA segments, with fluorescent probes—small molecules with active optical properties. Then, using a f...
Life Sciences |Using precision techniques for making superconducting thin films layer-by-layer, physicists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory have identified a single layer ...
Power and Electrical Engineering |Pregnant women who catch the flu are at serious risk for flu-related complications, including death, and that risk far outweighs the risk of possible side effects from injectable vaccines containing k...
Health and Medicine |Scott Valastyan, lead author on the study, describes it as presenting "detailed mechanistic insight regarding the process of tumor metastasis, and identifies several key regulators of this proces...
Life Sciences |In a paper published in Nature today*, researchers describe how the body converts an ingredient found in fish oils into another chemical called Resolvin D2 and how this chemical reduces the inflammati...
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