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16 matches found for "signaling lymphocyte activation molecule"
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Protein helps immune cells to divide and conquer
The rapid generation of large numbers of these immune cells is critical to the body's antibody defense mechanism. However, when B cells grow unchecked, it can lead to immune cell cancers such as ...
Life Sciences |
Read moreDouble trouble
Variations in a single gene simultaneously increase the risk of two autoimmune conditions Japanese researchers have identified two single nucleotide polymorphisms (SNPs), each of which signifi...
Life Sciences | Read moreSilencing a protein could kill T-Cells, reverse leukemia
Researchers say the breakthrough could provide more efficient ways of targeting diseases such as leukemia, and help in the potential development of vaccines for viruses that cause AIDS.The hum...
Life Sciences | Read moreSurvival Mechanism of T lymphocytes Uncovered
One particular important class of white blood cells are the so-called T lymphocytes. These cells originate in the bone marrow and mature in the thymus, hence called ‘T’ cells. Once matured, these cell...
Life Sciences | Read moreSt. Jude researchers find key step in programmed cell death
Investigators at St. Jude Children’s Research Hospital have discovered a dance of proteins that protects certain cells from undergoing apoptosis, also known as programmed cell death. Understanding the...
Life Sciences | Read moreMolecular 'trip switch' shuts down inflammatory response
Without these critical molecules — known as TAM receptor tyrosine kinases — patrolling immune cells on the look-out for danger would never cease activating the body’s defense system once they find an ...
Life Sciences | Read moreHow we sense microbes: Genetic Dissection of innate immunity in insects and mammals
The fundamental challenges.Infections have always been among the principal causes of death in the human species. In the developed world, microbes may be perceived as "manageable" bec...
Life Sciences | Read moreGlue inside the cell: Ubiquitin builds up an immune response
A study headed by the Junior Group of Dr. Daniel Krappmann (GSF - National Research Center for Environment and Health, Institute of Toxicology) in collaboration with Dr. Jürgen Ruland (TU Munich) and ...
Life Sciences | Read more'Super' enzyme may lead way to better tumor vaccines
"By keeping the dendritic cells alive longer, you extend the window of activation, promoting the desirable immune response, which in the case of cancer, is the expansion of T-cells," said Dr...
Life Sciences | Read morePNAS study reveals why organs fail following massive trauma
Massive trauma, say from a sabertooth tiger attack, meant immediate death for the primitive human. Modern man is more likely to survive severe injury caused by a car crash, gunshot or fall thanks to h...
Life Sciences | Read moreScientists Create a New Way to Study T Cell Signaling
An experiment that began as a “fantasy pipe dream” just three years ago is now a reality. Researchers with the Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of Cal...
Life Sciences | Read moreLIAI scientists discover cellular switch for controlling immune system function
Research could lead to future treatment advancements for rheumatoid arthritis and other autoimmune diseases A major finding by researchers at the La Jolla Institute for All...
Life Sciences | Read moreGenes tied to abnormal immune response in mice with lupus
Scientists have uncovered a link between a family of genes and abnormalities of the immune system that are associated with systemic lupus erythematosus (SLE), a devastating disease that a...
Life Sciences | Read moreNew protein structure may aid in design of therapeutics for autoimmune disease
Scientists have determined the crystal structure of a protein kinase C (PKC) isozyme, in this case the novel PKC family member PKC theta (PKCČ). This structure should prove extremely useful...
Life Sciences | Read moreScientists Identify Cell Defects that Limit Immune System’s Impact on Late-Stage Tumors
Although vaccines developed to help the immune system fight tumors appear to have an impact against early-stage tumors, they have little if any success in slowing the growth of tumors in later...
Health and Medicine | Read more
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