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83 matches found for "siRNA"

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Placing Active Agents in the Body with "Mini-Containers"

Jena scientists from different disciplines founded a new network in order to utilize so-called nanocontainers for applications in the biomedical field ("NanoConSens"). The research collabora...

Life Sciences | nachricht Read more
Reactive Oxygen’s Role in Metastasis

Sara Courtneidge, Ph.D., professor and director of the Tumor Microenvironment Program at Burnham’s NCI-designated Cancer Center, and colleagues have found that inhibiting reactive oxygen reduces invad...

Health and Medicine | nachricht Read more
KERatin - 3D skin model for autosomal recessive congenital ichthyosis (ARCI)

The pathophysiology of autosomal recessive congenital ichthyosis (ARCI) is still large unknown. Treatment of this heterogeneous group of severe disorders is symptomatic and often insufficient. For pha...

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U-Iowa improves delivery of cancer-fighting molecules

University of Iowa researchers have modified siRNA so that it can be injected into the bloodstream and impact targeted cells while producing fewer side effects. The findings, which were based on anima...

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Aurora B answers an XIST-ential question

Early in development, mammalian female cells counteract their double dose of X chromosomes by coating one of them with a large RNA named XIST. The RNA binds to the same X chromosome from which it is t...

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Researchers from CIC bioGUNE have found a way to treat ischemic pathologies

The results of this research project, which was initiated in 2005 and is supported by Bizkaia:Xede and the Basque Government's Etortek programme, were published in the prestigious scientific jour...

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Parasites ready to jump

Transposons are mobile genetic elements found in the hereditary material of humans and other organisms. They can replicate and the new copies can insert at novel sites in the genome. Because this thre...

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Scientists block Ebola infection in cell-culture experiments

Researchers at the University of Texas Medical Branch at Galveston have discovered two biochemical pathways that the Ebola virus relies on to infect cells. Using substances that block the activation o...

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Targeted Gene Suppression in Cancer Cells - Four-in-One

As they report in the journal Angewandte Chemie, their work involves magnetic iron oxide particles with a fluorescence dye, RNA fragments, and a special peptide attached.The peptide is present...

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Small molecules might block mutant protein production in Huntington's disease

These man-made molecules also were effective against the abnormal protein that causes Machado-Joseph disease, a neurological condition similar to Huntington’s.The work has been done only in cu...

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Study identifies human genes required for hepatitis C viral replication

Massachusetts General Hospital (MGH) researchers are investigating a new way to block reproduction of the hepatitis C virus (HCV) – targeting not the virus itself but the human genes the virus exploit...

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Scientists at CSHL discover mobile small RNAs that set up leaf patterning in plants

A key item in the developmental agenda of a plant leaf is the establishment of an axis that makes a leaf's top half distinct from its bottom half. This asymmetry is crucial for the leaf's fu...

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Researchers Identify Gene Linked to Aggressive Progression of Liver Cancer

Hepatocellular carcinoma, HCC, or liver cancer, is the fifth most common cancer and the third leading cause of cancer deaths in the world. Treatment options for HCC include chemotherapy, chemoemboliza...

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Making the switch for DNA

Two RIKEN researchers have developed a switch to control the formation and separation of DNA duplexes that may have implications in many biological processes, such as gene regulation.Formation...

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Silencing of jumping genes in pollen

Scientists at the Instituto Gulbenkian de Ciência (IGC), in Portugal, are to date the only research group in the world capable of isolating the sperm cells in the pollen grain of the model plant Arabi...

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