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22 matches found for "protein beta-catenin"

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Stanford discovery pinpoints new connection between cancer cells, stem cells

The unexpected finding may lead to new anticancer therapies and a greater understanding of how adult and embryonic stem cells divide and specialize."Telomerase is the factor that account...

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Scientists identify gene in breast cancer pathway

The findings could help predict whether breast tumors will metastasize and also reveal potential drug targets for preventing metastasis. The study will appear in the May 20th online edition of the Jou...

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Scientists uncover indicator that warns leukemia is progressing to more dangerous form

The findings may provide physicians with an indicator of when this type of cancer – chronic myeloid leukemia (CML) – is progressing, enabling them to make more accurate prognoses for the disease and i...

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Stem cell research uncovers mechanism for type 2 diabetes

Their findings, published online January 9 in Experimental Diabetes Research, could provide a potential new target for therapy.Pamela Itkin-Ansari, Ph.D., assistant adjunct professor at the UC...

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Heart regenerates after Infarction - First trials with mice

Now, researchers and cardiologists from the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch and the Charité (Germany) have been able to show that this dogma no longer holds true. ...

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'Hub' of fear memory formation identified in brain cells

The results are published online this week and appear in the October issue of Nature Neuroscience. The protein beta-catenin acts like a Velcro strap, fastening cells' internal skeletons t...

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Robert Weinberg: Research Can Begin to Rationalize Complex Process of the Development of Metastases

The reason for this is the discovery of transcription factors in the last few years. "Transcription factors are proteins that turn genes on and off and can act to program many of the traits of hi...

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2-way cell talk provides clues about neuromuscular disease

In an animal model, Medical College of Georgia researchers have shown that if a muscle cell fails to produce the protein beta-catenin, its neuron doesn’t develop or function properly.Their fin...

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Pourquié lab links beta-catenin gradient to process of somite formation

The team analyzed the somite segmentation process that results in the formation of the vertebral column. This process is thought to be controlled by two components: a molecular oscillator (the segment...

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Heads or tails? Scientists identify gene that regulates polarity in regenerating flatworms

Mechanisms have been sought to explain this process of regeneration polarity for over 100 years, but until now, little was known about how planaria can regenerate heads and tails at their proper sites...

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A gene for metastasis

Colorectal cancer is one of the most prevalent cancers in the Western world. The tumor starts off as a polyp but then turns into an invasive and violent cancer, which often spreads to the liver. In an...

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Enzyme eliminated by cancer cells holds promise for cancer treatment

In a high-stakes tit for tat, protein kinase G enables healthy cells to stay on task to proliferate, differentiate then provide a useful function. Cancer somehow reduces or eliminates PKG and cells...

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Marine worm opens new window on early cell development

University of Oregon biologists studying a common ocean-dwelling worm have uncovered potentially fundamental insights into the evolutionary origin of genetic mechanisms, which when compromised in huma...

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How does a zebrafish grow a new tail?

If a zebrafish loses a chunk of its tail fin, it'll grow back within a week. Like lizards, newts, and frogs, a zebrafish can replace surprisingly complex body parts. A tail fin, for example, has ...

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Lost in the labyrinth

Blood cells have limited lifespans, which means that they must be continually replaced by calling up reserves, and turning these into the blood cell types needed by the body. Claus Nerlov and his coll...

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