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19 matches found for "polycystic kidney disease"
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Some brain tumors may be mediated by tiny filament on cells
The study, conducted in mice and in human brain tissue of medulloblastomas, coincides with a study by another team of UCSF scientists showing that the structure, known as primary cilium, also may play...
Life Sciences |
Read moreMutations in gene linked to ciliopathies
Ciliopathies are a newly emerging group of diseases caused by defects in the function or structure of cellular primary cilia, which are small, cellular appendages of previously unknown function. Examp...
Life Sciences | Read moreScientists Identify Critical Protein Complex in Formation of Cell Cilia
The new report, published this week by Developmental Cell and selected as the featured publication of the open-access online edition, describes how three proteins work together to regulate the formati...
Life Sciences | Read moreRong Li Lab Identifies New Role of Inflammatory Protein in Polycystic Kidney Disease and a Possible Treatment
The discovery was published in the advance online publication of Nature Medicine 15 June. The team showed that a pro-inflammatory cytokine protein — tumor necrosis factor- á (TNF-á) — dis...
Life Sciences | Read moreCan you feel the heat? Your cilia can
Humans and genetically engineered mice lacking functional cilia respond more slowly to physical sensations such as exposure to hot water or a sharp poke with a stick. Results of the study, appearing i...
Life Sciences | Read moreGreen alga genome project catalogs carbon capture machinery
The genome analysis of a tiny green alga has uncovered hundreds of genes that are uniquely associated with carbon dioxide capture and generation of biomass. Among the 15,000-plus genes revealed in the...
Life Sciences | Read moreLoss of cell's 'antenna' linked to cancer's development
Submarines have periscopes. Insects have antennae. And increasingly, biologists are finding that most normal vertebrate cells have cilia, small hair-like structures that protrude like antennae into th...
Life Sciences | Read moreTriptolide: A potential drug for polycystic kidney disease
Over 12 million people worldwide suffer from PKD, a genetic disorder that causes uncontrolled growth of cells lining tubules in the kidneys, and results in the formation of many, large fluid-filled cy...
Health and Medicine | Read moreGenetic research at Children's Hospital of Pittsburgh reinforces theory of evolution
There are approximately 20,000 pseudogenes in the human and other mammalian genomes. In recent years, there has been growing discussion about the nature of these pseudogenes. The issue centers on whet...
Life Sciences | Read moreA New Way of Looking at Molecular Motors
An innovative method of categorizing myosin—one of three molecular “motors” that produce movement within the cells of the body—has dramatically increased the amount of information available ...
Life Sciences | Read moreScientists find genetic pathway that could lead to drugs for kidney disease
Scientists at the University of California, Santa Barbara have reported a discovery at the cellular level that suggests possibilities for drug therapy for kidney disease. ...
Life Sciences | Read morePolycystic kidney disease
NIH and PKD Foundation launch HALT-PKD treatment trials The National Institutes of Health (NIH) and the PKD Foundation have launched two treatment trials for autosomal dom...
Health and Medicine | Read moreKeeping biological tubes in check: New insights into tube size morphogenesis
The function of tubular organs like the kidneys, lungs, and vessels of the vascular system is critically dependent on the length and diameter of the tubular branches of which they are compo...
Life Sciences | Read moreMayo collaboration identifies gene in childhood kidney disease
New insight into related disorders An international research collaboration led by Mayo Clinic has identified a new gene involved in causing the inherited kidney disorder, M...
Life Sciences | Read moreNewly identified enzyme group converts protein into cellular traffic signal
An international research team has identified a new group of enzymes that may help uncover how cells direct internal traffic. The discovery has future implications for conditions -- such a...
Life Sciences | Read more
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