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22 matches found for "phosphodiesterase"

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Viagra relatives may shrink abnormally large hearts

In heart failure, which affects about 5.7 million Americans, the heart gradually loses the ability to pump with enough force to supply the body with blood. One reason for lost pumping strength is the ...

Health and Medicine | nachricht Read more
New biomarker may predict leukemia aggressiveness

They found that high levels of a particular enzyme in the blood are an indicator that chronic lymphocytic leukemia (CLL) – the most common form of adult leukemia – will be aggressive and in need of im...

Life Sciences | nachricht Read more
Atomic-resolution views suggest function of enzyme that regulates light-detecting signals in eye

An atomic-resolution view of an enzyme found only in the eye has given researchers at the University of Washington (UW) clues about how this enzyme, essential to vision, is activated. The enzyme, phos...

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Study shows PDE5 inhibitor more effective when used on-demand in erectile dysfunction

87 centres across Europe, the US, Canada and South Africa participated between December 2004 and September 2007.Nerve-sparing radical prostatectomy (NSRP) is the gold-standard therapy for pros...

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The drugs blocked an enzyme and opened blood vessels to tumors but not normal brain

In a study using laboratory animals, researchers found that medications commonly prescribed for erectile dysfunction opened a mechanism called the blood-brain tumor barrier and increased delivery of c...

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Mainz University involved in new DFG Collaborative Research Center in the field of immune responses

If this defense system fails, conditions such as allergies and autoimmune diseases can develop. The German Research Foundation (Deutsche Forschungsgemeinschaft - DFG) has now approved a research appli...

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Abnormal 'editing' of gene messages may be a cause of lupus

The findings, reported online in the journal Immunology, involve an enzyme that “edits” and modifies the messages of genes before the protein-making process. It is protein molecules that carry out the...

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Erectile dysfunction may signal a broken heart

One of the studies also showed that cholesterol-lowering medications could cut the risk of heart problems by about one-third—and suggested that Viagra and other compounds in the same drug family might...

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Texas A&M testing oral contraceptives for animals

Researchers are testing oral contraceptives – used in much the same way as in humans – and the results are promising, says Duane Kraemer, a professor in veterinary physiology and pharmacology and a wo...

Agricultural and Forestry Science | nachricht Read more
Study finds Viagra increases release of key reproductive hormone

The finding is the first indication of a chemical mechanism through which erectile dysfunction drugs like Viagra may have physical effects besides increasing blood flow to sexual organs, says study au...

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Scientists identify specific enzymes that make meningitis hard to fight

The study found that the two enzymes - which have distinct functions - work together to hamper the body's efforts to fight off the disease. Together they repair damage done to the meningitis bact...

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No Link Found Between Erectile Medications and HIV

Recent reports have appeared, however, that some individuals have misused this class of drug, combining them with narcotics such as methamphetamines. These reports further note that such individuals ...

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Leveling the field for babies with persistent pulmonary hypertension

“When these kids are born, you have a short amount of time to intervene or you get brain damage,” says Dr. Black, cell and molecular physiologist at the Medical College of Georgia Vascular Biology Cen...

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New study shows antibiotic may protect the heart

In the July issue of the Journal of Molecular and Cellular Cardiology, the official publication of the International Society for Heart Research, researchers demonstrated for the first time that pretre...

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VCU study shows Levitra may protect the heart

The widely used erectile dysfunction drug Levitra is now the second drug in its class found to protect the heart against tissue damage following acute heart attack, according to a ne...

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