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Cognitive dysfunction reversed in mouse model of Down syndrome
The study, published in Science Translational Medicine on November 18, revealed two important new findings about Down's syndrome in a mouse model: 1) there is evidence that synaptic terminals inv...
Life Sciences |
Read moreNew Down syndrome treatment suggested by Stanford/Packard study in mice
Now, findings from the Stanford University School of Medicine and Lucile Packard Children's Hospital shed light on the neural basis of memory defects in Down syndrome and suggest a new strategy f...
Health and Medicine | Read moreNew Panel PC and Industrial LCD monitors with key operation
For the Panel PCs Simatic HMI IPC477C and HMI IPC577C there are now 12" and 15" devices with keys in addition to the 12", 15" and 19" devices with touch screen. For the Simati...
Power and Electrical Engineering | Read moreWistar researchers show targeting 'normal' cells in tumors slows growth
Targeting the normal cells that surround cancer cells within and around a tumor is a strategy that could greatly increase the effectiveness of traditional anti-cancer treatments, say researchers at Th...
Life Sciences | Read moreResearchers find potential treatment for Huntington's disease
Investigators at Burnham Institute for Medical Research (Burnham), the University of British Columbia's Centre for Molecular Medicine and Therapeutics and the University of California, San Diego ...
Health and Medicine | Read moreLearning more about physiological endoplasmic reticulum stress using the ERAI system
Takao IwawakiInitiative Research ScientistIwawaki Initiative Research UnitRIKEN Advanced Science InstituteThe endoplasmic reticulum is a cell organelle that acts as a processing fa...
Life Sciences | Read moreMouse gene suppresses Alzheimer's plaques and tangles
Investigators at Burnham Institute for Medical Research (Burnham) and colleagues have identified a novel mouse gene (Rps23r1) that reduces the accumulation of two toxic proteins that are major players...
Life Sciences | Read moreResearchers discover mechanism of insulin production that can lead to better treatment for diabetes
Their work opens the way for a new understanding of possible paths to battle diabetes and diabetes-related health problems, which are on the rise all over the world. Blood glucose levels are ...
Life Sciences | Read moreDrug shrinks lung cancer tumors in mice
The authors of the research, from Imperial College London, are now planning to take the drug into clinical trials, to establish whether it could offer hope to patients with an inoperable form of lung ...
Health and Medicine | Read moreHybrid Molecules Show Promise for Exploring, Treating Alzheimer's
In order to answer that key question and develop new approaches to preventing the damage, scientists must first understand how amyloid-beta forms the telltale clumps.University of Michigan res...
Life Sciences | Read moreTwo genes co-operate to cause aggressive leukaemia
The two genes are often present in mutated form in acute leukaemias, but the mutations rarely occur together. Scientists have previously believed that the two mutated genes have exactly the same funct...
Life Sciences | Read moreStem Cell Therapy May Offer Hope for Acute Lung Injury
Their results are reported online in the October issue of the journal Stem Cells. Acute lung injury (ALI) is responsible for an estimated 74,500 deaths in the U.S. each year. ALI can be caused...
Life Sciences | Read moreNew 'schizophrenia gene' prompts researchers to test potential drug target
The rescue, described as “surprisingly complete” by the researchers, was accomplished with rapamycin, a drug known to act on a protein called mTOR whose role involves the production of other proteins....
Life Sciences | Read moreNew Chromosomal Abnormality Identified in Leukemia Associated with Down Syndrome
The findings have already resulted in new diagnostic tests and potential tools for tracking a patient’s response to treatment. The research, led by scientists from St. Jude Children’s Research Hospita...
Life Sciences | Read moreAlzheimer mice: Microglia cells are neither involved in formation nor clearance of amyloid deposits
In the brains of Alzheimer patients deposits of patholgical amyloid-beta protein, so-called amyloid plaques, are found. Since amyloid-beta protein plays a key role in the pathogenesis of Alzheimer...
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