These cells, known as circulating tumor cells, or CTCs, can provide critical information for examining and diagnosing cancer metastasis, determining patient prognosis, and monitoring the effectiveness...
Life Sciences |"PSA is the gold standard for following prostate cancer patients after they receive radiation or surgery. But we haven't know if having PSA rise sooner means a patient has a greater danger o...
Studies and Analyses |Scott Valastyan, lead author on the study, describes it as presenting "detailed mechanistic insight regarding the process of tumor metastasis, and identifies several key regulators of this proces...
Life Sciences |At the moment, doctors rely on biopsy analysis to determine the progression of eye cancer. However, researchers now believe that a new technology, bioluminescence imaging (BLI), will allow doctors to ...
Medical Engineering |Scientists at the Singapore Immunology Network (SIgN) have determined how the master gene regulator p53 could switch a gene in a cell "on" or "off" by recognizing specific sequence...
Life Sciences |Scientists observed that cancer stem cells taken from the gastrointestinal system in patients with a chronic digestive disease called ulcerative colitis will transform into cancerous tumors in mice....
Life Sciences |"Leptin receptor expression may be a useful molecular marker in predicting the level of aggression of Middle Eastern thyroid cancer that can help guide treatment options and follow-up care,"...
Health and Medicine |Deaths of most breast-cancer patients are the result of metastasis, a complex, multi-step, and poorly understood process. “Identifying the gene that suppresses the spread of tumor cells and the mechan...
Life Sciences |Researchers at Fox Chase Cancer Center have demonstrated that a protein called NEDD9 may be required for some of the most aggressive forms of breast cancer to grow. Their findings, based on the study ...
Health and Medicine |The researchers refer to these microRNA collections as signatures, and their study results are reported in the September 15 issue of “Genes & Development.’’ The study, available online at http://genes...
Life Sciences |Sara Courtneidge, Ph.D., professor and director of the Tumor Microenvironment Program at Burnham’s NCI-designated Cancer Center, and colleagues have found that inhibiting reactive oxygen reduces invad...
Health and Medicine |Primary lung cancer shifts to metastatic disease by suppressing a family of small molecules that normally locks the tumor in a noninvasive state, researchers at The University of Texas M. D. Anderson ...
Life Sciences |“We have discovered a key molecular mechanism for the deadly transition of non-invasive breast cancer into invasive disease,” said senior author Dihua Yu, M.D., Ph.D., professor in M. D. Anderson’s De...
Health and Medicine |Cancer stem cells have many characteristics of stem cells and are thought to be the cells that drive tumor formation. The researchers report that STAT3 could become a target for cancer therapy, specif...
Life Sciences |In an article in the Aug. 9, 2009 online edition of Nature Medicine, they report the identification of a new molecule known as soluble VEGFR-2 that blocks lymphangiogenesis – the growth of lymphatics ...
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