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Cancer Research Institute Announces Winner of 2009 Frederick Alt Award for New Discoveries in Immunology
CRI presented the award to Dr. Rao during a special reception and dinner for CRI-funded graduate students and postdoctoral fellows held the evening of September 30 at The Harvard Club in New York City...
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Read more'Achilles' heel' in Y chromosome linked to sex disorders
Roughly six years ago, David Page's lab at Whitehead Institute for Biomedical Research reported the discovery of eight large areas of mirror-imaged genetic sequences, or palindromes, along the Y ...
Life Sciences | Read moreResearchers Identify Protein–telomere Interactions That Could be Key in Treating Cancer, Other Diseases
Since this RNA also facilitates the formation of DNA at telomeres—a process that can protect aging cells and destabilize tumor cells—manipulating its expression may be useful in treating cancer and ot...
Life Sciences | Read moreSea lamprey jettison one-fifth of their genome
Researchers have discovered that the sea lamprey, which emerged from jawless fish first appearing 500 million years ago, dramatically remodels its genome. Shortly after a fertilized lamprey egg divide...
Life Sciences | Read moreVariations in 5 genes raise risk for most common brain tumors
Common genetic variations spread across five genes raise a person's risk of developing the most frequent type of brain tumor, an international research team reports online in Nature Genetics....
Life Sciences | Read moreResearch Team Finds Key Target of Aging Regulator
Scientists have long known that a class of proteins called sirtuins promotes fitness and longevity in most organisms ranging from single-celled yeast to mammals. At the cellular level, sirtuins protec...
Life Sciences | Read moreAluminum-Oxide Nanopore Beats Other Materials For DNA Analysis
The nanopore sensor, made by drilling a tiny hole through a thin film of aluminum oxide, could ultimately prove capable of performing DNA analysis with a single molecule, offering tremendous possibili...
Life Sciences | Read moreNew Rockefeller Faculty Member Studies Mechanisms of DNA Repair
Dr. Smogorzewska, who received her Ph.D. at Rockefeller University in 2002 under the tutelage of Titia de Lange, head of the Laboratory of Cell Biology and Genetics, and her M.D. from Weill Cornell Me...
Life Sciences | Read moreDNA barcoding of mosquito species deployed in bid to end elephantiasis
New biotechnologies that allow scientists to quickly and accurately distinguish species based on a simple DNA analysis are being creatively deployed for the first time in the war against a major globa...
Life Sciences | Read moreGenetic switch potential key to new class of antibiotics
Researchers have determined the structure of a key genetic mechanism at work in bacteria, including some that are deadly to humans, in an important step toward the design of a new class of antibiotics...
Life Sciences | Read moreDid increased gene duplication set the stage for human evolution?
Segments of DNA in its genome began to form duplicate copies at a greater rate than in the past, creating an instability that persists in the genome of modern humans and contributes to diseases like a...
Life Sciences | Read moreResearchers Illuminate Mechanisms that Regulate DNA Damage Control, Replication
Since Ddk is often deregulated in human cancers, this new understanding of its role in DNA damage control could help shape new cancer therapies. The research was published in the December 24 issue of ...
Life Sciences | Read moreA cellular task force to safeguard genome stability
A recent study, published in Nature, now sheds light on a complex regulatory system based on sumoylation and ubiquitination, two important regulatory processes involved in DNA repair and, consequently...
Life Sciences | Read moreResearchers Identify a Potentially Universal Mechanism of Aging
This is the first time that such an evolutionarily conserved aging mechanism has been identified between such diverse organisms. The mechanism probably dates back more than one billion years. The stud...
Health and Medicine | Read moreCancer Research Institute Names Six New Investigator Award Winners
The six scientists are conducting basic and tumor immunology laboratory investigations at distinguished academic institutions throughout the United States, as well as in Greece and Japan. Areas of res...
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