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The Protein Srebp2 Drives Cholesterol Formation in Prion-Infected Neuronal Cells Which May Promote Prion-Dependent Diseases
Prions are causing fatal and infectious diseases of the nervous system, such as the mad cow disease (BSE), scrapie in sheep or Creutzfeldt-Jakob disease in humans. Scientists of Helmholtz Zentrum Münc...
Life Sciences |
Read moreImmune system activated in schizophrenia
Scientists at Karolinska Institutet have now been able to analyse inflammatory substances in the spinal fluid of patients with schizophrenia, instead of, as in previous studies, in the blood. The resu...
Health and Medicine | Read moreScientists find molecular trigger that helps prevent aging and disease
An answer lies in a two-part study led by Charles Mobbs, PhD, Professor of Neuroscience and of Geriatrics and Palliative Medicine at Mount Sinai School of Medicine, published in the November 17 editio...
Life Sciences | Read moreScientists discover cells that control inflammation in chronic disease
The authors of the study, from Imperial College London, the Istituto Dermopatico dell'Immacolata in Rome and the Center of Allergy and Environment (ZAUM) in Munich, hope their discovery could lea...
Life Sciences | Read moreWorld's first delivery of intra-arterial Avastin directly into brain tumor
Neurosurgeons from NewYork-Presbyterian Hospital/Weill Cornell Medical Center performed the world's first intra-arterial cerebral infusion of Avastin (bevacizumab) directly into a patient's ...
Health and Medicine | Read moreNew Down syndrome treatment suggested by Stanford/Packard study in mice
Now, findings from the Stanford University School of Medicine and Lucile Packard Children's Hospital shed light on the neural basis of memory defects in Down syndrome and suggest a new strategy f...
Health and Medicine | Read moreNutrigenomics Researchers Replicate Gene Interaction With Saturated Fat
Men and women carrying the CC genotype demonstrated higher body mass index (BMI) scores and a higher incidence of obesity, but only if they consumed a diet high in saturated fat. These associations we...
Life Sciences | Read moreHow Cells Tolerate DNA Damage – MDC Researchers Identify Start Signal for Cell Survival Program
Dr. Michael Stilmann, Dr. Michael Hinz and Professor Claus Scheidereit have shown that the protein PARP-1, which detects DNA damage within seconds, activates the transcription factor NF-kappaB, a well...
Life Sciences | Read moreAre sterile mosquitoes the answer to malaria elimination?
The supplement, edited by Dr Mark Benedict, who along with the other editors led the development of this technology at the International Atomic Energy Agency in Vienna, describes how SIT may be used a...
Life Sciences | Read moreUCI researchers create compound that boosts anti-inflammatory fat levels
UC Irvine pharmacology researchers have discovered a way to boost levels of a natural body fat that helps decrease inflammation, pointing to possible new treatments for allergies, illnesses and injur...
Health and Medicine | Read moreWistar researchers show targeting 'normal' cells in tumors slows growth
Targeting the normal cells that surround cancer cells within and around a tumor is a strategy that could greatly increase the effectiveness of traditional anti-cancer treatments, say researchers at Th...
Life Sciences | Read moreNew combination therapy could deliver powerful punch to breast cancer
While they are powerful killers of some breast cancer cells, new drugs called histone deacetylase inhibitors, or HDAC inhibitors, also increase self-digestion, or autophagy, in surviving, mega-stresse...
Health and Medicine | Read moreAnalyzing structural brain changes in Alzheimer's disease
By applying the techniques to the newly completed dataset of the multi-institution Alzheimer's Disease Neuroimaging Initiative (ADNI), the scientists demonstrated that such sub-regional brain vol...
Studies and Analyses | Read moreLargest gene study of childhood IBD identifies 5 new genes
In the largest, most comprehensive genetic analysis of childhood-onset inflammatory bowel disease (IBD), an international research team has identified five new gene regions, including one involved in ...
Studies and Analyses | Read moreTiny particles can deliver antioxidant enzyme to injured heart cells
Injecting the enzyme-containing particles into rats' hearts after a simulated heart attack reduced the number of dying cells and resulted in improved heart function days later. Michael Da...
Life Sciences | Read more
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