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118 matches found for "double-strand"

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Nanoparticles Found in Common Household Items Caused Genetic Damage in Mice

The TiO2 nanoparticles induced single- and double-strand DNA breaks and also caused chromosomal damage as well as inflammation, all of which increase the risk for cancer. The UCLA study is the first t...

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Single-stranded DNA-binding protein proven dynamic, critical to DNA repair

Their study, of SSB in the bacterium Escherichia coli, appears today in the journal Nature.Whenever the double helix of DNA unravels, exposing each strand to the harsh environment of the cell,...

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Models Begin to Unravel How Single DNA Strands Combine

Present in the cells of all living organisms, DNA is composed of two intertwined strands and contains the genetic “blueprint” through which all living organisms develop and function. Individual strand...

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A flash of light turns graphene into a biosensor

Biomedical researchers suspect graphene, a novel nanomaterial made of sheets of single carbon atoms, would be useful in a variety of applications. But no one had studied the interaction between graphe...

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RNA Interference Found in Budding Yeasts

RELEVANCE: Some budding yeasts cause human diseases, while other budding yeasts are used in research as models for more complicated organisms, in industry to create beer and biofuels, and in pharmaceu...

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Small Molecule Inhibits Pathology Associated With Myotonic Dystrophy Type 1

The new compound, soon to be tested in cells, binds tightly to its target, an abnormally elongated RNA that hijacks part of the normal cellular machinery and brings on symptoms of the disease. The new...

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The Pressure is on to Eradicate Deadly Organism Affecting Citrus Crops Worldwide

Americans may find a glass of their favorite breakfast staple, orange juice, hard to come by in the next few years if a certain bacteria has its way. According to a spokesperson with the Florida Citr...

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UNC researchers decode structure of an entire HIV genome

The study, the cover story in the Aug. 6, 2009, issue of the journal Nature, also opens the door for further research which could accelerate the development of antiviral drugs.HIV, like the vi...

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Link uncovered between viral RNA and human immune response

The key lies in a virus' RNA -- a long molecular chain often used to make proteins -- and how it regulates an enzyme called protein kinase R (PKR), according to researchers from Penn State, the U...

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Scientists track impact of DNA damage in the developing brain

Switching off a key DNA repair system in the developing nervous system is linked to smaller brain size as well as problems in brain structures vital to movement, memory and emotion, according to new r...

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Baylor researchers unravel mystery of DNA conformation

The interaction represented produced the famous explanation of the structure of DNA, but the model pictured is a stiff snapshot of idealized DNA. As researchers from Baylor College of Medicine...

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Scripps research scientists observe human neurodegenerative disorder in fruit flies

A team of scientists from The Scripps Research Institute, Katholeike Universiteit Leuven, and the University of Antwerp, Belgium, among other institutions, has created a genetically modified fruit fly...

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Researchers Solve Another Mystery in B Lymphocyte Development

Researchers led by Jane A. Skok Ph.D., assistant professor in the Department of Pathology at NYU School of Medicine and a member of the NYU Cancer Institute, showed that the V(D)J recombinase, which c...

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Targeted Gene Suppression in Cancer Cells - Four-in-One

As they report in the journal Angewandte Chemie, their work involves magnetic iron oxide particles with a fluorescence dye, RNA fragments, and a special peptide attached.The peptide is present...

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New Disease Discovered

The DNA is being damaged continuously: It is affected by solar UV radiation just as by toxic substances from the environment. However, defects also occur during cell division: For this, the DNA has to...

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