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184 matches found for "dendritic"

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Dendritic cells spark smoldering inflammation in smokers' lungs

What sparks that smoldering destruction remained a mystery until a consortium of researchers led by Baylor College of Medicine found that certain dendritic cells in the lung – the cells that "pre...

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Large-scale study probes how cells fight pathogens

Scientists have deciphered a key molecular circuit that enables the body to distinguish viruses from bacteria and other microbes, providing a deep view of how immune cells in mammals fend off differen...

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Promising new target emerges for autoimmune diseases

University of Michigan scientists say they have uncovered a fundamentally new mechanism that holds in check aggressive immune cells that can attack the body’s own cells. The findings open a new avenue...

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Traffic jam in brain causes schizophrenia symptoms

Schizophrenia waits silently until a seemingly normal child becomes a teenager or young adult. Then it swoops down and derails a young life.Scientists have not understood what causes the sever...

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Scientists make multiple types of white blood cells directly from embryonic and adult stem cells

While clinical use is some years away, the new technique could produce cells with enormous potential for studying the development and treatment of disease. The technique works equally well with stem c...

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Unexpected reservoir of monocytes discovered in the spleen

It takes a spleen to mend a broken heart – that's the conclusion of a surprising new report from researchers at the Massachusetts General Hospital (MGH) Center for Systems Biology, directed by Ra...

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Study may explain why HIV progresses faster in women than in men with same viral load

One of the continuing mysteries of the HIV/AIDS epidemic is why women usually develop lower viral levels than men following acute HIV-1 infection but progress faster to AIDS than men with similar vira...

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Natural suppressors of a treatment-induced disease

Researchers in Japan have shown that mouse dendritic cells (DCs), which can promote or inhibit inflammation depending on the proteins displayed on their surface, include a subpopulation that exerts be...

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Study identifies biomarker that safely monitors tumor response to new brain cancer treatment

The finding, reported in the July 1 issue of Clinical Cancer Research, paves the way for a Phase 1 clinical trial expected to begin in late 2009. The gene therapy is a two-pronged strategy dev...

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New fuel cell catalyst uses 2 metals

Material scientists at Washington University in St. Louis have developed a technique for a bimetallic fuel cell catalyst that is efficient, robust and two to five times more effective than commercial ...

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Autopilot Guides Proteins in Brain

“There’s no little man sitting there, putting the protein in the right place,” said Don Arnold, a molecular and computational biologist at USC College.“Proteins have to have in them encoded in...

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Dendritic cells ensure immune tolerance

The only way to protect against these afflictions is to destroy all immune factors that turn against the body’s own tissue – in other words: immune tolerance. A team working with LMU researche...

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TB breakthrough could lead to stronger vaccine

Bacille Calmette-Guérin (BCG) provides only partial protection against tuberculosis (TB) in children and is ineffective in adults. As a result, tuberculosis still kills almost 2 million people a year ...

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Increased understanding of immune system activation

To understand how different materials are taken up and what happens within the cells can for example facilitate the development of new vaccines."The immune system is a large and important...

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New origin found for a critical immune response

"This finding will have important implications in vaccine science and autoimmune disease therapy development," said Michael Gunn, M.D., an immunologist and cardiologist at Duke and senior au...

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