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ID3 provides career counseling for blood progenitors, driving the creation of gamma-delta T cells
Like an unusually forceful career counselor, the Id3 protein decides the fate of a given white blood cell precursor, according to researchers at Fox Chase Cancer Center. Their findings, published toda...
Life Sciences |
Read moreStudy finds promise in combined transplant/vaccine therapy for high-risk leukemia
In a study to be published in the online early edition of the Proceedings of the National Academy of Sciences the week of Aug. 24, the researchers report that patients with high-risk acute myeloid leu...
Studies and Analyses | Read moreScientists make multiple types of white blood cells directly from embryonic and adult stem cells
While clinical use is some years away, the new technique could produce cells with enormous potential for studying the development and treatment of disease. The technique works equally well with stem c...
Life Sciences | Read moreMGH study identifies first molecular steps to childhood leukemia
A Massachusetts General Hospital (MGH)-based research team has identified how a chromosomal abnormality known to be associated with acute lymphoblastic leukemia (ALL) – the most common cancer in child...
Life Sciences | Read moreAmniotic Fluid May Provide New Source of Stem Cells for Future Therapies
“Building on observations made by other scientists, our research team wondered whether hematopoietic stem cells could be detected in amniotic fluid. We looked at the capacity of these cells to...
Life Sciences | Read moreResearch Shows Cell’s Inactive State is Critical for Effectiveness of Cancer Treatment
According to the study’s findings, researchers identified the genetic pathway used to maintain a cell’s quiescence, a state that allows bone marrow cells to escape the lethal effects of standard cance...
Life Sciences | Read moreStem cells and leukemia battle for marrow microenvironment
Learning how leukemia takes over privileged "niches" within the bone marrow is helping researchers develop treatment strategies that could protect healthy blood-forming stem cells and improv...
Life Sciences | Read moreGenes hold secret to survival of Antarctic 'antifreeze fish'
The study, in the Proceedings of the National Academy of Sciences, is the first to search the genome of an Antarctic notothenioid fish for clues to its astounding hardiness.There are eight fam...
Life Sciences | Read moreEvidence for an increased cancer risk following the use of radioactive Radium-224 in the therapy for Ankylosing Spondylitis
Ankylosing Spondylitis (Bechterew’s Disease) is a painful chronic inflammatory rheumatic disease, associated with stiffening of the vertrebral column. Between 100,000 and 150,000 cases have already be...
Studies and Analyses | Read moreMicroenvironment a main driver of aggressive multi-lineage leukemia disease type
Research led by scientists at Cincinnati Children's Hospital Medical Center has revealed new clues into what causes different types of a particularly aggressive group of blood cancers known as mi...
Life Sciences | Read moreBone Cells Found to Influence Blood Stem Cell Replication and Migration
The finding, published online in May in the journal Blood, improves understanding of how such stem cells work and could have implications for the future of bone marrow and peripheral blood progenitor ...
Life Sciences | Read moreSt. Jude researchers find key step in programmed cell death
Investigators at St. Jude Children’s Research Hospital have discovered a dance of proteins that protects certain cells from undergoing apoptosis, also known as programmed cell death. Understanding the...
Life Sciences | Read moreTransparent fish to make human biology clearer
Zebrafish are genetically similar to humans and are good models for human biology and disease. Now, researchers at Children's Hospital Boston have created a zebrafish that is transparent througho...
Life Sciences | Read moreUnique role for blood formation gene identified
All blood cell production in adults depends on the steady work of a vital gene that if lost results in early bone marrow failure, Dartmouth Medical School cancer geneticists have found. Their research...
Life Sciences | Read moreA faster way to recover from chemotherapy and marrow transplant
Researchers at Children’s Hospital Boston report finding a new way to increase stem cells in blood, suggesting a possible treatment to help patients who undergo chemotherapy or bone marrow transplant ...
Life Sciences | Read more
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