Experiments show that infected red blood cells are stiffer and stickier than normal ones -- in the later stages of the disease, up to 10 times stiffer. They also tend to adhere to the endothelial cell...
Physics and Astronomy |Promising results have led to the design of a clinical trial that will soon be under way to test a compound -- called PU-H71 -- in human patients. This compound is in a new class of drugs, called heat...
Life Sciences |A commonly inherited gene deletion can increase the likelihood of immune complications following bone marrow transplantation, an international team of researchers reports in the November 22 advance on...
Life Sciences |Physician-scientists from Weill Cornell Medical College have discovered a molecular mechanism that may prove to be a powerful target for the treatment of non-Hodgkin's lymphoma, a type of cancer ...
Life Sciences |A protein known to stimulate blood vessel growth has now been found to be responsible for the cell overgrowth in the development of polyps that characterize one of the most severe forms of sinusitis, ...
Health and Medicine |For the first time, scientists have successfully used a method called exome sequencing to quickly discover a previously unknown gene responsible for a mendelian disorder. Mendelian disorders, ...
Life Sciences |Although the research has been carried out using mice and cultured cells, it could lead to a new medicine for human beings, which could be given to patients who have had a stroke or other disorders th...
Health and Medicine |These cells, known as circulating tumor cells, or CTCs, can provide critical information for examining and diagnosing cancer metastasis, determining patient prognosis, and monitoring the effectiveness...
Life Sciences |The authors of the study, from Imperial College London, the Istituto Dermopatico dell'Immacolata in Rome and the Center of Allergy and Environment (ZAUM) in Munich, hope their discovery could lea...
Life Sciences |Neurosurgeons from NewYork-Presbyterian Hospital/Weill Cornell Medical Center performed the world's first intra-arterial cerebral infusion of Avastin (bevacizumab) directly into a patient's ...
Health and Medicine |The largest national stem cell study for heart disease showed the first evidence that transplanting a potent form of adult stem cells into the heart muscle of subjects with severe angina results in le...
Life Sciences |Targeting the normal cells that surround cancer cells within and around a tumor is a strategy that could greatly increase the effectiveness of traditional anti-cancer treatments, say researchers at Th...
Life Sciences |While they are powerful killers of some breast cancer cells, new drugs called histone deacetylase inhibitors, or HDAC inhibitors, also increase self-digestion, or autophagy, in surviving, mega-stresse...
Health and Medicine |These results suggest that healthy adults may have a level of protective immune memory that can blunt the severity of infection caused by the 2009 H1N1 influenza virus.The study team was led b...
Health and Medicine |Injecting the enzyme-containing particles into rats' hearts after a simulated heart attack reduced the number of dying cells and resulted in improved heart function days later. Michael Da...
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