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376 matches found for "birth defect"

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Common plastics chemicals linked to ADHD symptoms

Phthalates are important components of many consumer products, including toys, cleaning materials, plastics, and personal care items. Studies to date on phthalates have been inconsistent, with some li...

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Causative gene of a rare disorder discovered by sequencing only protein-coding regions of genome

For the first time, scientists have successfully used a method called exome sequencing to quickly discover a previously unknown gene responsible for a mendelian disorder. Mendelian disorders, ...

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New Down syndrome treatment suggested by Stanford/Packard study in mice

Now, findings from the Stanford University School of Medicine and Lucile Packard Children's Hospital shed light on the neural basis of memory defects in Down syndrome and suggest a new strategy f...

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Chromosomes dance and pair up on the nuclear membrane

Meiosis – the pairing and recombination of chromosomes, followed by segregation of half to each egg or sperm cell – is a major crossroads in all organisms reproducing sexually. Yet, how the cell preci...

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Research Reveals Lipid’s Unexpected Role in Triggering Death of Brain Cells

The work provides the first evidence that a lipid can initiate the suicidal, or apoptotic, response in cells. The findings involve a lipid called GM1-ganglioside. Lipids are fat-like molecules. GM1 bu...

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Learning more about physiological endoplasmic reticulum stress using the ERAI system

Takao IwawakiInitiative Research ScientistIwawaki Initiative Research UnitRIKEN Advanced Science InstituteThe endoplasmic reticulum is a cell organelle that acts as a processing fa...

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Research reveals lipids' unexpected role in triggering death of brain cells

The lipid that accumulates in brain cells of individuals with an inherited enzyme disorder also drives the cell death that is a hallmark of the disease, according to new research led by St. Jude Child...

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Stanford scientists turn stem cells into precursors for sperm, eggs

Researchers at the school have devised a way to efficiently coax the cells to become human germ cells — the precursors of egg and sperm cells — in the laboratory. Unlike previous research, which yield...

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Boys with urogenital birth defects are 33 percent more common in villages sprayed with DDT

Women who lived in villages sprayed with DDT to reduce malaria gave birth to 33 per cent more baby boys with urogenital birth defects (UGBD) between 2004 and 2006 than women in unsprayed villages, acc...

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Treating depression in pregnancy

Depression is not uncommon in pregnant women. Between 14 and 23% of pregnant women will experience a depressive disorder while pregnant. In 2003, approximately 13% of pregnant women took an anti-depre...

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Landmark study sheds new light on human chromosomal birth defects

That discovery is groundbreaking, but so, too, is what principal investigator Hong-Guo Yu calls the "genetics trick" performed by his research team that made the discovery possible. The stud...

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Researchers restore missing protein in rare genetic brain disorder

Reduced levels of that protein have been shown to cause the rare brain disorder lissencephaly, which is characterized by brain malformations, seizures, severe mental retardation and very early death i...

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Scripps research scientists identify genetic cause for type of deafness

A team led by scientists from The Scripps Research Institute has discovered a genetic cause of progressive hearing loss. The findings will help scientists better understand the nature of age-related d...

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Secrets of the 4 chambers revealed by reptile hearts

The first genetic link in the evolution of the heart from three-chambered to four-chambered has been found, illuminating part of the puzzle of how birds and mammals became warm-blooded. Frogs ...

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Gladstone scientists find first genetic link between reptile and human heart evolution

Scientists at the Gladstone Institute of Cardiovascular Disease (GICD) have traced the evolution of the four-chambered human heart to a common genetic factor linked to the development of hearts in tur...

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