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An answer lies in a two-part study led by Charles Mobbs, PhD, Professor of Neuroscience and of Geriatrics and Palliative Medicine at Mount Sinai School of Medicine, published in the November 17 editio...
Life Sciences |Investigators at Burnham Institute for Medical Research (Burnham) and colleagues have identified a novel mouse gene (Rps23r1) that reduces the accumulation of two toxic proteins that are major players...
Life Sciences |While too much amyloid beta protein in the brain is linked to the development of Alzheimer's disease, not enough of the protein in healthy brains can cause learning problems and forgetfulness, Sa...
Health and Medicine |In order to answer that key question and develop new approaches to preventing the damage, scientists must first understand how amyloid-beta forms the telltale clumps.University of Michigan res...
Life Sciences |In fact, inflammation helps clear the brain of these noxious amyloid plaques early in the disease development, as seen from studies in mice that are predisposed to the disorder, say the researchers in...
Life Sciences |A-beta-autoantibodies were isolated from the serum of Alzheimer patients. The cDNA and amino acid sequences of the variable regions of the heavy and the light chains were determined and all possible p...
Technology Offerings |In the brains of Alzheimer patients deposits of patholgical amyloid-beta protein, so-called amyloid plaques, are found. Since amyloid-beta protein plays a key role in the pathogenesis of Alzheimer...
Life Sciences |Sandra Rossie, a professor of biochemistry, found that increasing the amount of protein phosphatase 5, or PP5, in rat neural cells resulted in less cell death associated with reactive oxygen species, ...
Life Sciences |The findings, available online in the journal Proceedings of the National Academy of Sciences, suggest a promising new tactic against the devastating illness, the researchers said.The harmful ...
Health and Medicine |The substance is a beta-amyloid protein called Abeta16. The thesis shows in two independent studies that Alzheimer's patients have higher levels of the protein in their spinal fluid than do healt...
Life Sciences |The results were published in this week's edition of the Journal of the American Medical Association (JAMA).Alzheimer's is one of the most common dementia disorders. Around 160,000 p...
Health and Medicine |The study by Jennifer Palmer, BRACE/Reverend Williams PhD Scholar and colleagues at the University of Bristol's Dementia Research Group is published in the current issue [July 2009] of the Americ...
Health and Medicine |Undesirable protein deposits in the islets of Langerhans, the area of the pancreas that makes glucose-controlling hormones, are increased even when blood sugar levels are barely above normal, accordin...
Life Sciences |The early research findings, which appear in the July issue of the Journal of Alzheimer's Disease, may lead to new approaches in preventing and treating Alzheimer's by utilizing the property...
Life Sciences |The anti-inflammatory drug indomethacin could hold promise as a treatment for Alzheimer's disease, says a Saint Louis University doctor and researcher.Two research studies published by Wi...
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