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Largest gene study of childhood IBD identifies 5 new genes
In the largest, most comprehensive genetic analysis of childhood-onset inflammatory bowel disease (IBD), an international research team has identified five new gene regions, including one involved in ...
Studies and Analyses |
Read moreResearchers find new way to attack inflammation in Graves' eye disease
A small group of patients with severe Graves' eye disease experienced rapid improvement of their symptoms — and improved vision — following treatment with the drug rituximab. Inflammation around...
Health and Medicine | Read moreGeneticists Hunt for Scleroderma Triggers
In all its forms, scleroderma gives Dartmouth geneticist Michael Whitfield, his graduate students, and his postdoctoral researchers a sense of urgency in their search for the triggers of the chronic c...
Life Sciences | Read moreDendritic cells spark smoldering inflammation in smokers' lungs
What sparks that smoldering destruction remained a mystery until a consortium of researchers led by Baylor College of Medicine found that certain dendritic cells in the lung – the cells that "pre...
Health and Medicine | Read moreNew findings connect diet and intestinal bacteria with healthier immune systems
The indigestible part of all plant-based foods pushes its way through most of the digestive tract unchanged, acting as a kind of internal broom. When it arrives in the colon, bacteria convert it to en...
Health and Medicine | Read moreNew therapy for vasculitis will help patients avoid infertility and cancer
"The reason this is a big deal is that this is a disease where people would come in and be told 'listen, we are probably going to be able to get on top of your life-threatening disease by us...
Health and Medicine | Read moreOpen Lid Reveals Mercury
Mercury, the silvery liquid formerly used in thermometers, is now known to be highly toxic. The worst of the toxins are organic mercury compounds, such as methylmercury.Most previous analytica...
Life Sciences | Read moreUnusual bacteria help balance the immune system in mice
Medical researchers have long suspected that obscure bacteria living within the intestinal tract may help keep the human immune system in balance. An international collaboration co-led by scientists a...
Life Sciences | Read moreID3 provides career counseling for blood progenitors, driving the creation of gamma-delta T cells
Like an unusually forceful career counselor, the Id3 protein decides the fate of a given white blood cell precursor, according to researchers at Fox Chase Cancer Center. Their findings, published toda...
Life Sciences | Read moreStrategy for mismatched stem cell transplants triggers protection against graft-vs.-host disease
Analysis of blood samples from a small number of clinical trial patients showed that the novel method -- which inactivates specific immune cells from the donor that would attack the recipient's b...
Health and Medicine | Read moreNew link found between osteoporosis and coeliac disease
It is the first time an autoimmune response – a condition whereby the body can attack itself – has been shown to cause damage to bones directly. Researchers from the University of Edinburgh st...
Health and Medicine | Read moreNational report shines light on lupus 50-year treatment drought
Today, The Lewin Group, a national health care consulting firm, issued recommendations on ways to overcome the barriers that have obstructed lupus drug development resulting in no new drug approval fo...
Health and Medicine | Read moreMechanism for potential Friedreich's ataxia drug uncovered
Using clever chemistry, a Scripps Research team has pinpointed the enzyme target of a drug group that stops the progression of the devastating disease Friedreich's ataxia in mice and may do the s...
Life Sciences | Read moreBuilding a Complete Metabolic Model
Investigators at Burnham Institute for Medical Research (Burnham), University of California, San Diego (UC San Diego), The Scripps Research Institute (TSRI), Genomics Institute of the Novartis Researc...
Life Sciences | Read moreMaster gene that switches on disease-fighting cells identified by scientists
The researchers have 'knocked out' the gene in question, known as E4bp4, in a mouse model, creating the world's first animal model entirely lacking NK cells, but with all other blood ce...
Life Sciences | Read more
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