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Researchers find new way to attack inflammation in Graves' eye disease
A small group of patients with severe Graves' eye disease experienced rapid improvement of their symptoms — and improved vision — following treatment with the drug rituximab. Inflammation around...
Health and Medicine |
Read moreUnusual bacteria help balance the immune system in mice
Medical researchers have long suspected that obscure bacteria living within the intestinal tract may help keep the human immune system in balance. An international collaboration co-led by scientists a...
Life Sciences | Read moreMechanism for potential Friedreich's ataxia drug uncovered
Using clever chemistry, a Scripps Research team has pinpointed the enzyme target of a drug group that stops the progression of the devastating disease Friedreich's ataxia in mice and may do the s...
Life Sciences | Read moreMaster gene that switches on disease-fighting cells identified by scientists
The researchers have 'knocked out' the gene in question, known as E4bp4, in a mouse model, creating the world's first animal model entirely lacking NK cells, but with all other blood ce...
Life Sciences | Read moreUM scientists pinpoint critical molecule to celiac disease, possibly other autoimmune disorders
It was nine years ago that University of Maryland School of Medicine researchers discovered that a mysterious human protein called zonulin played a critical role in celiac disease and other autoimmune...
Health and Medicine | Read moreLarge-scale study probes how cells fight pathogens
Scientists have deciphered a key molecular circuit that enables the body to distinguish viruses from bacteria and other microbes, providing a deep view of how immune cells in mammals fend off differen...
Life Sciences | Read morePromising new target emerges for autoimmune diseases
University of Michigan scientists say they have uncovered a fundamentally new mechanism that holds in check aggressive immune cells that can attack the body’s own cells. The findings open a new avenue...
Life Sciences | Read moreFound: A gene that may play a role in type 1 diabetes
The study team, led by C. Garrison Fathman, M.D., examined genes from mice that develop a type 1 diabetes-like disease. Dr. Fathman is a grantee of the National Institute of Allergy and Infectious Dis...
Life Sciences | Read moreGene linked to increasingly common type of blood cancer
California and Arizona researchers have identified a gene variant that carries nearly twice the risk of developing an increasingly common type of blood cancer, according to a study published online to...
Life Sciences | Read moreVitamin D Sufficiency Challenges and Opportunities for the Food Industry
It may play a role in preventing autoimmune diseases such as multiple sclerosis and rheumatoid arthritis, some types of cancer (breast, ovarian, colorectal and prostate).Advancing technologies...
Health and Medicine | Read moreAnxiety and depression lower quality of life in majority of systemic lupus erythematosus patients
In the study, 92.8% (52 of 56) of the patients who were diagnosed with SLE had an element of confirmed neuropsychiatric (NP) involvement (including anxiety, depression, mild cognitive deficits and maj...
Health and Medicine | Read moreOne size does not fit all
Statins, a commonly prescribed class of drugs used by millions worldwide to effectively lower blood cholesterol levels, may actually have a negative impact in Multiple Sclerosis (MS) patients treated ...
Health and Medicine | Read moreLice can be nice to us
Jan Bradley, Professor of Parasitology, said: “Our understanding of mammalian immunology is largely based on rodents reared under highly unnatural pathogen and stress-free conditions. Analysing the im...
Life Sciences | Read moreScripps scientists find structure of a protein that makes cancer cells resistant to chemotherapy
The protein, called P-glycoprotein or P-gp for short, is one of the main reasons cancer cells are resistant to chemotherapy drugs. Understanding its structure may help scientists design more effective...
Life Sciences | Read moreFireflies and jellyfish help illuminate quest for cause of infertility
Scientists are using the luminescent and florescent genes to illuminate cells that produce a hormone linked to conditions, which include rheumatoid arthritis and lupus.The technique will help ...
Life Sciences | Read more
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