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While long-term tamoxifen use among breast cancer survivors decreases their risk of developing the most common, less aggressive type of second breast cancer, such use is associated with a more than fo...
Studies and Analyses |"This is good news for women with a family history of breast cancer," says Alison Stuebe, assistant professor of obstetrics and gynecology at the University of North Carolina at Chapel Hill ...
Studies and Analyses |The key player in this process is a cytotoxic T cell molecule which has been known for a long time and which scientists have named EBAG9. Cancer researchers Dr. Constantin Rüder and Dr. Armin Rehm tog...
Life Sciences |An FDA-approved drug used for preventing recurrence of breast cancer shows promise in fighting life-threatening fungal infections common in immune-compromised patients, such as infants born prematurel...
Health and Medicine |DACH1, a cell fate determination factor protein, prevents cancer cell proliferation by repressing the function of estrogen receptorsƒnin breast cancer, the researchers found. However, they also found ...
Life Sciences |The research is significant in helping determine why tamoxifen and other synthetic estrogens are linked to increased rates of endometriosis and uterine cancer, and identifies a pathway that could be t...
Studies and Analyses |Sherene Loi, from the Peter MacCallum Cancer Centre, Melbourne, worked with a team of Australian and Belgian researchers to investigate the differences between those estrogen receptor positive (ER+) c...
Studies and Analyses |Women at increased risk for breast cancer because of the genetic BRCA mutations are more likely to think a prophylactic mastectomy is the best way to reduce their risk for the disease, compared to oth...
Studies and Analyses |The molecular details of Aromatase, the key enzyme required for the body to make estrogen, are no longer a mystery thanks to the structural biology work done by the Ghosh lab at the Hauptman-Woodward ...
Life Sciences |A team of researchers co-ordinated by Dr. Stephen Hiscox, from the Welsh School of Pharmacy at Cardiff University, investigated the selective oestrogen receptor modulator (SERM) tamoxifen on human bre...
Health and Medicine |When it comes to understanding the effectiveness and safety of using herbal therapies with other drugs, much is unknown. Now, a University of Missouri researcher will study how black cohosh - an herba...
Health and Medicine |"This kind of information provides a target for the production of drugs against cancer," said Dr. Bert O'Malley, chair of molecular and cellular biology at BCM. "One can already fi...
Life Sciences |“We are at a crucial moment in our fight against cancer,” said ESMO President Prof. Jose Baselga. “We have never before made so much progress in our fight to eradicate cancer as a cause of death, and ...
Health and Medicine |The first research to look at recent trends in European cancer incidence, mortality and survival together has shown that cancer prevention and management in Europe is moving in the right direction. Ho...
Health and Medicine |“This cell-based study is exciting because it suggests these compounds are likely to be effective in tumors that remain dependent on estrogen for growth but are resistant to current therapies,” said p...
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