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8 matches found for "PDE5"

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Viagra relatives may shrink abnormally large hearts

In heart failure, which affects about 5.7 million Americans, the heart gradually loses the ability to pump with enough force to supply the body with blood. One reason for lost pumping strength is the ...

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Atomic-resolution views suggest function of enzyme that regulates light-detecting signals in eye

An atomic-resolution view of an enzyme found only in the eye has given researchers at the University of Washington (UW) clues about how this enzyme, essential to vision, is activated. The enzyme, phos...

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Study points to potential new use for Viagra

Led by professor of Pharmacology and Toxicology Donald Maurice, the study focuses on the effects of Viagra – the popular erectile dysfunction drug, which is also used to treat pulmonary hypertension....

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Study shows PDE5 inhibitor more effective when used on-demand in erectile dysfunction

87 centres across Europe, the US, Canada and South Africa participated between December 2004 and September 2007.Nerve-sparing radical prostatectomy (NSRP) is the gold-standard therapy for pros...

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Tadalafil Shows Promise for Relief of Lower Urinary Tract Symptoms Associated with Benign Prostatic Hyperplasia

Researchers from the University of Texas Southwestern Medical Center at Dallas, Northwestern University and Lilly Research Laboratories report on a randomized, double-blind, placebo-controlled study o...

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The drugs blocked an enzyme and opened blood vessels to tumors but not normal brain

In a study using laboratory animals, researchers found that medications commonly prescribed for erectile dysfunction opened a mechanism called the blood-brain tumor barrier and increased delivery of c...

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Viagra blunts effects of stress on the human heart

Sildenafil citrate (Viagra), a drug used to treat erectile dysfunction (ED) in millions of men, reduces the stimulatory effects of hormonal stress on the heart by half, according to result...

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Sildenafil effectively treats enlarged hearts, mouse study shows

Researchers at Johns Hopkins have found that sildenafil citrate (Viagra), a drug used to treat erectile dysfunction (ED) in millions of men, effectively treats enlarged hearts in mice, sto...

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