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412 matches found for "Neurotransmitter"

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Researchers Begin to Decipher Metabolism of Sexual Assault Drug

Now, a team of Ohio and Michigan scientists have determined new routes by which 4-HB is metabolized by the body. “This is new and important information,” said K. Michael Gibson, professor and chair of...

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Cognitive dysfunction reversed in mouse model of Down syndrome

The study, published in Science Translational Medicine on November 18, revealed two important new findings about Down's syndrome in a mouse model: 1) there is evidence that synaptic terminals inv...

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New Down syndrome treatment suggested by Stanford/Packard study in mice

Now, findings from the Stanford University School of Medicine and Lucile Packard Children's Hospital shed light on the neural basis of memory defects in Down syndrome and suggest a new strategy f...

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'Despair' Gene May Link to Mood Disorders

Pharmacy scientists at the University of Maryland, Baltimore (UMB) have identified antidepressant and anti-anxiety behaviors in tests of mice lacking the gene. Writing in the journal BMC Neuro...

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CSHL team solves structure of NMDA receptor unit that could be drug target for neurological diseases

A team of scientists at Cold Spring Harbor Laboratory (CSHL) reports on Thursday their success in solving the molecular structure of a key portion of a cellular receptor implicated in Alzheimer's...

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Gene knockout may cheer up mice

Elisabeth Barbier and Jia Bei Wang, from the School of Pharmacy at the University of Maryland, USA, carried out the experiments to investigate the role of the gene in regulating mood function. Wang, t...

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Why antidepressants don't work for so many

More than half the people who take antidepressants for depression never get relief. Why? Because the cause of depression has been oversimplified and drugs designed to treat it aim at the wrong...

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Now Hear This: Scientists Show How Tiny Cells Deliver Big Sound

Now, reporting on rat experiments in the October 22 issue of Nature, a Johns Hopkins team says it has for what is believed to be the first time managed to measure and record the elusive electrical act...

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Fine-tuning treatments for depression

Current drugs for depression target the regulatory process for neurotransmitters, and while effective in some cases, do not appear to work in other cases. Recent findings suggest that synuclei...

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Study supports possible role of urate in slowing Parkinson's disease progression

By examining data from a 20-year-old clinical trial, a research team based at the MassGeneral Institute for Neurodegenerative Diseases (MGH-MIND) and Harvard School of Public Health (HSPH), has found ...

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Researchers find a key mechanism in the development of nerve cells

Under the leadership of Academy Research Fellow Sari Lauri, a team of researchers at the University of Helsinki has been studying for years how a neural network capable of processing information effec...

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New links among alcohol abuse, depression, obesity in young women found

Using data collected when young adults were 24, 27 and 30 years of age, a team of University of Washington researchers found that nearly half the sample of 776 young adults tracked during the study me...

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Photoswitches shed light on spontaneous free swimming in zebrafish

A new way to select and switch on one cell type in an organism using light has helped answer a long-standing question about the function of one class of enigmatic nerve cells in the spinal cord....

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Gene called flower missing link in vesicle uptake in neurons

The extra membrane is then captured in a process called endocytosis and recycled to form a new vesicle to enable the next cycle of release. Most important, exocytosis must be tightly coupled with endo...

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UF scientists construct 'off switch' for Parkinson therapy

A common antibiotic can function as an "off switch" for a gene therapy being developed for Parkinson's disease, according to University of Florida researchers writing online in advance ...

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