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How Cells Tolerate DNA Damage – MDC Researchers Identify Start Signal for Cell Survival Program
Dr. Michael Stilmann, Dr. Michael Hinz and Professor Claus Scheidereit have shown that the protein PARP-1, which detects DNA damage within seconds, activates the transcription factor NF-kappaB, a well...
Life Sciences |
Read moreFirst International Graduate School for Skeletal Muscle Diseases - Partners: MDC, Charité, Université Pierre et Marie Curie Pari
The German Research Foundation (DFG) and the Université Pierre et Marie Curie Paris VI (UPMC), Paris, France are now establishing the first international, structured PhD program in myology at the Expe...
Life Sciences | Read moreMDC Scientists Show How Hematopoietic Stem Cell Development Is Regulated
These were the findings of researchers at the laboratory of Dr. Frank Rosenbauer of the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch in cooperation with the laboratory of Professor Ste...
Life Sciences | Read moreProfessor Jens Reich Received Carl Friedrich von Weizsäcker Award
The physician, bioinformatician, molecular biologist and GDR civil rights activist received the award for his exceptional scientific achievements and his personal and political courage. The award was ...
Awards Funding | Read moreMDC Researchers Discover Molecule Responsible for Axonal Branching
Through the ramification of its fiber-like axon, a single neuron can send branches and thus transmit information into several target areas at the same time. In principle, neurobiologists distinguish b...
Life Sciences | Read moreKetamine reduces suicidality in depressed patients
Researchers have now explored ketamine's effects on suicidality in patients with treatment-resistant depression, and are publishing their results in the September 1st issue of Biological Psychiat...
Health and Medicine | Read moreEstrogen-Dependent Switch Tempers Killing Activity of Immune Cells
The key player in this process is a cytotoxic T cell molecule which has been known for a long time and which scientists have named EBAG9. Cancer researchers Dr. Constantin Rüder and Dr. Armin Rehm tog...
Life Sciences | Read moreHormone levels contribute to stress resilience
It is important to understand what biological mechanisms contribute to an individual's capacity to be resilient under conditions of extreme stress, such as those regularly experienced by soldiers...
Life Sciences | Read moreGliomas exploit Immune Cells of the Brain for Rapid Expansion
As a result, surgery can never completely remove the tumor. Now, the neurosurgeons Dr. Darko S. Markovic (Helios Klinikum Berlin-Buch) and Dr. Michael Synowitz (Charité) as well as Dr. Rainer Glass an...
Life Sciences | Read moreColorectal Cancer - MDC Researchers Identify Genetic Markers for Metastasis Formation
Now, researchers of the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch and Charité - University Medicine Berlin, Germany, have identified 115 genes that are disregulated both in the prim...
Life Sciences | Read moreNew Control System of the Body Discovered - Important Modulator of Immune Cell Entry into the Brain
Together with researchers in Canada and the USA they showed that this bradykinin receptor 1 (B1) controls the infiltration of immune cells into the CNS. When they activated B1 in mice with encephaliti...
Life Sciences | Read moreRadiation Dose Drastically Reduced During Whole Chest MDCT
Prospective ECG triggering enables the CT scanner to monitor the ECG signal of several heart beats in real time and turns the radiation beam on only during alternate beats; retrospective ECG gating al...
Health and Medicine | Read moreLack of "Happiness Hormone" Serotonin in the Brain Causes Impaired Maternal Behavior in Mice
This was the result of research conducted by Dr. Natalia Alenina, Dana Kikic, and Professor Michael Bader of the Max Delbrück Center (MDC) Berlin-Buch, Germany. They also discovered that the presence ...
Life Sciences | Read moreInvestigating the Development of Mechanosensitivity
By measuring electrical impulses in the sensory neurons of mice, the neurobiologists and pain researchers Dr. Stefan G. Lechner and Professor Gary Lewin were able to directly elucidate, for the first ...
Life Sciences | Read moreMDC Researchers Unravel Key Mechanism in Pathogenesis of Osteoporosis
Researchers of the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch, Germany, have now elucidated a molecular mechanism which regulates the equilibrium between bone formation and bone reso...
Life Sciences | Read more
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