The work provides the first evidence that a lipid can initiate the suicidal, or apoptotic, response in cells. The findings involve a lipid called GM1-ganglioside. Lipids are fat-like molecules. GM1 bu...
Life Sciences |The lipid that accumulates in brain cells of individuals with an inherited enzyme disorder also drives the cell death that is a hallmark of the disease, according to new research led by St. Jude Child...
Life Sciences |All fifty-eight patients, with a median age of 63 and all with advanced acute myeloid leukemia or high-risk myelodysplastic syndrome – a pre-leukemic condition – saw their blood cancers go into remiss...
Health and Medicine |The indigestible part of all plant-based foods pushes its way through most of the digestive tract unchanged, acting as a kind of internal broom. When it arrives in the colon, bacteria convert it to en...
Health and Medicine |Colitis is a disease in which the inner tissue of the colon, the mucosa, becomes inflamed and damaged and can result in painful sores. Ulcerative colitis and Crohn’s disease are the two major types of...
Life Sciences |If the mechanism that plants use to defend themselves can be understood, it will be possible to produce plants that are resistant to disease. The Plant Immunity Research Group is also undertaking rese...
Life Sciences |Since 1999, Yoshiyuki Takizawa has been working on the Extreme Universe Space Observatory (EUSO), an international project to develop a super wide-field telescope capable of observing large volumes of...
Physics and Astronomy |Like an unusually forceful career counselor, the Id3 protein decides the fate of a given white blood cell precursor, according to researchers at Fox Chase Cancer Center. Their findings, published toda...
Life Sciences |Commonly used in agriculture and medicine, these chemical compounds were not previously known to act on the T1R3 receptor. The T1R3 receptor is a critical component of both the sweet taste rec...
Life Sciences |Although not as well known as bacterial infections, such as MRSA and E.coli, fungal infections such as that caused by the yeast Candida albicans can be more serious and lead to a higher death rate. Us...
Health and Medicine |A new study published in the September issue of The Journal of Nuclear Medicine shows that positron emission tomography (PET)/computer tomography (CT) scans with the imaging agent choline could detect...
Medical Engineering |Molecular physiologist Marc Van Gilst, Ph.D., and colleagues report that during starvation, sexually mature adult worms stop ovulating and the germline component of their reproductive system – the sex...
Life Sciences |Toxoplasmosis is generally a mild infection, but it can have serious and potentially fatal effects in pregnant women, their fetuses and others with weakened immune systems.In mice, T gondii di...
Life Sciences |The key player in this process is a cytotoxic T cell molecule which has been known for a long time and which scientists have named EBAG9. Cancer researchers Dr. Constantin Rüder and Dr. Armin Rehm tog...
Life Sciences |Effective response by key immune cells in the body, called T cells, is crucial for control of many widespread chronic viral infections such as HIV and hepatitis B and C. Virus-specific CD8 T cells, al...
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