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16 matches found for "GVHD"

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Gene mismatch influences success of bone marrow transplants

A commonly inherited gene deletion can increase the likelihood of immune complications following bone marrow transplantation, an international team of researchers reports in the November 22 advance on...

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Strategy for mismatched stem cell transplants triggers protection against graft-vs.-host disease

Analysis of blood samples from a small number of clinical trial patients showed that the novel method -- which inactivates specific immune cells from the donor that would attack the recipient's b...

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Study finds promise in combined transplant/vaccine therapy for high-risk leukemia

In a study to be published in the online early edition of the Proceedings of the National Academy of Sciences the week of Aug. 24, the researchers report that patients with high-risk acute myeloid leu...

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Natural suppressors of a treatment-induced disease

Researchers in Japan have shown that mouse dendritic cells (DCs), which can promote or inhibit inflammation depending on the proteins displayed on their surface, include a subpopulation that exerts be...

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Donor Cells for Immune Therapy

Such cells control aggressive immune cells and, thus, unwanted immune reactions by the graft can be avoided. However, to date, there were no adequate techniques available to securely isolate the regul...

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The world's first transplant of both arms at the “Klinikum rechts der Isar” of the TU in Munich

The patient is doing well under the circumstances. This operation was managed by the Clinic for Plastic Surgery and Hand Surgery (Director Prof. Hans-Günther Machens). The operation, with a team of 40...

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Grafts against cancer

A research team led by Prof. Claude Perreault, Université de Montréal, is announcing a major discovery in Genomics. This will generate a fundamental impact on the treatment of blood cancers (leukemias...

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New hope for children when leukemia treatment fails

Clinicians at St. Jude Children's Research Hospital have successfully demonstrated an improved technique for blood stem cell transplantations in children that shows promise for those most likely ...

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UWE helps fight leukaemia with research into ‘natural killer’ cells

Scientists at the University of the West of England and the Bone Marrow Transplant Unit at the Bristol Children’s Hospital have just won funding for a two-year project aimed at improvin...

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Rare immune cell is key to transplant’s cancer-killing effect

U-M discovery could help make bone marrow transplants more effective and an option for more patients Researchers at the University of Michigan’s Comprehensive Cancer C...

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Largest study of unrelated bone marrow transplantation for leukemia serves as benchmark

Multi-institutional study addresses critical GVHD complication Together with 16 other institutions in the United States, University of Minnesota researchers led the largest ...

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Impaired neuromotor function following cancer treatment can improve

Patients who suffer a loss of cognitive and motor function as a result of stem cell transplantation for severe blood disorders are likely to see those functions return to previous levels af...

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Transplant rejection averted by simple light exposure in Stanford animal study

One of the unfortunate side effects of bone marrow and stem cell transplantation is that the newly implanted cells often stage an internal attack against the patient they’re intended to he...

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Newborn Testing for Immune Disorders Could Save Lives

A simple, inexpensive blood test performed at birth to screen for immune disorders could dramatically increase the chance of survival for babies born with such potentially fatal disorders as se...

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Regulatory T cells keep graft-versus-host disease in check

Bone marrow transplantation offers the hope of a complete cure for patients suffering from certain forms of cancer, such as leukemia or other immune deficiency diseases. However, ther...

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