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Nanoparticles Found in Common Household Items Caused Genetic Damage in Mice
The TiO2 nanoparticles induced single- and double-strand DNA breaks and also caused chromosomal damage as well as inflammation, all of which increase the risk for cancer. The UCLA study is the first t...
Life Sciences |
Read moreHow Cells Tolerate DNA Damage – MDC Researchers Identify Start Signal for Cell Survival Program
Dr. Michael Stilmann, Dr. Michael Hinz and Professor Claus Scheidereit have shown that the protein PARP-1, which detects DNA damage within seconds, activates the transcription factor NF-kappaB, a well...
Life Sciences | Read moreLearning more about physiological endoplasmic reticulum stress using the ERAI system
Takao IwawakiInitiative Research ScientistIwawaki Initiative Research UnitRIKEN Advanced Science InstituteThe endoplasmic reticulum is a cell organelle that acts as a processing fa...
Life Sciences | Read moreNo-entry zones for AIDS virus
Like all retroviruses, the AIDS virus (HIV) integrates its DNA into the genome of the infected cell. As integration sites, HIV usually prefers active genes that are transcribed frequently. This is adv...
Life Sciences | Read morePenn Study Provides First Clear Idea of How Rare Bone Disease Progresses
An international team of scientists, led by researchers at the University of Pennsylvania School of Medicine, is taking the first step in developing a treatment for a rare genetic disorder called fibr...
Studies and Analyses | Read moreNew explanation for nature's hardiest life form
Spore-forming bacteria, present almost everywhere in our environment, can also cause serious infectious diseases, such as tetanus, anthrax, and botulism.Now researchers from Lund University an...
Life Sciences | Read moreResearchers Use Drug-radiation Combo to Eradicate Lung Cancer
In a study appearing in the October issue of Cancer Research, UT Southwestern researchers found that if they administered BEZ235 before they damaged the DNA of tumor cells with otherwise nontoxic radi...
Health and Medicine | Read moreScientists are first to observe the global motions of an enzyme copying DNA
Perpetuation of DNA mistakes can cause mutations that lead to cancer and other diseases.But before scientists can determine how and when errors are made during DNA replication, they must first...
Life Sciences | Read moreSingle-stranded DNA-binding protein proven dynamic, critical to DNA repair
Their study, of SSB in the bacterium Escherichia coli, appears today in the journal Nature.Whenever the double helix of DNA unravels, exposing each strand to the harsh environment of the cell,...
Life Sciences | Read moreLoss of Tumor-Suppressor and DNA-Maintenance Proteins Causes Tissue Demise
A study published in the October issue of Nature Genetics demonstrates that loss of the tumor-suppressor protein p53, coupled with elimination of the DNA-maintenance protein ATR, severely disrupts tis...
Studies and Analyses | Read moreSingapore scientists discover widely sought molecular key to understanding p53 tumor suppressor gene
Scientists at the Singapore Immunology Network (SIgN) have determined how the master gene regulator p53 could switch a gene in a cell "on" or "off" by recognizing specific sequence...
Life Sciences | Read moreResearcher solves mystery about proteins that package the genome
A Florida State University College of Medicine researcher has solved a century-old mystery about proteins that play a vital role in the transfer of the human genetic code from one cell to another. The...
Life Sciences | Read moreCanker disease in eucalyptus in the Basque Country
The expansion of rapid growth plantations such as those of eucalyptus came about in order to meet the needs of the growing paper pulp industry. Blights and diseases arose as one of the main threats to...
Agricultural and Forestry Science | Read moreReactive Oxygen Levels in Fruit Flies Act as a Cell Signaling Mechanism for Immune Response
Research at UCLA’s Jonsson Comprehensive Cancer Center has raised that question.It has been known for decades that reactive oxygen species (ROS) - ions or very small molecules that include fre...
Life Sciences | Read moreBarcoding endangered sea turtles
Conservation geneticists who study sea turtles have a new tool to help track this highly migratory and endangered group of marine animals: DNA barcodes. DNA barcodes are short genetic sequence...
Ecology, The Environment and Conservation | Read more
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