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Largest gene study of childhood IBD identifies 5 new genes
In the largest, most comprehensive genetic analysis of childhood-onset inflammatory bowel disease (IBD), an international research team has identified five new gene regions, including one involved in ...
Studies and Analyses |
Read moreProbiotic Is Effective Treatment for Colitis in Mice
Colitis is a disease in which the inner tissue of the colon, the mucosa, becomes inflamed and damaged and can result in painful sores. Ulcerative colitis and Crohn’s disease are the two major types of...
Life Sciences | Read moreUnusual bacteria help balance the immune system in mice
Medical researchers have long suspected that obscure bacteria living within the intestinal tract may help keep the human immune system in balance. An international collaboration co-led by scientists a...
Life Sciences | Read moreUF researchers find triggers in cells' transition from colitis to cancer
Scientists observed that cancer stem cells taken from the gastrointestinal system in patients with a chronic digestive disease called ulcerative colitis will transform into cancerous tumors in mice....
Life Sciences | Read morePromising new target emerges for autoimmune diseases
University of Michigan scientists say they have uncovered a fundamentally new mechanism that holds in check aggressive immune cells that can attack the body’s own cells. The findings open a new avenue...
Life Sciences | Read moreCounting duplicated genome segments now possible
A newly designed computational method has proven its usefulness in counting copies of duplicated genome sequences and in doing initial assessments of their contents, according to a study to be publish...
Life Sciences | Read moreCannibalistic Cells May Help Prevent Infections
Salmonella, the causative agent of salmonellosis, causes many of the intestinal infections and food-related illnesses reported in the U.S. About 600 people die each year as a result of these infection...
Life Sciences | Read moreLa Jolla Institute discovers novel tumor suppressor
La Jolla Institute for Allergy & Immunology researchers studying an enzyme believed to play a role in allergy onset, instead have discovered its previously unknown role as a tumor suppressor that may ...
Life Sciences | Read moreNovel genetic finding offers new avenue for future Crohn's disease treatment
Researchers from Case Western Reserve University School of Medicine identified a novel link between ITCH, a gene known to regulate inflammation in the body and NOD2, a gene which causes the majority o...
Life Sciences | Read moreToward an explanation for Crohn's disease?
Twenty-five per cent of Crohn's disease patients have a mutation in what is called the NOD2 gene, but it is not precisely known how this mutation influences the disease. The latest study ...
Life Sciences | Read moreImmune genes adapt to parasites
The study, conducted by a team of researchers in Italy, also suggests that you might blame parasites for sculpting some of those genes into risk factors for intestinal disorders. Parasite-driv...
Life Sciences | Read moreNo longer afraid to be a bridesmaid or travel with the boss
One of Laurie Keefer's patients was afraid to be a bridesmaid in a friend's wedding, others worried about traveling with the boss or even going to parties in peoples' homes.The ...
Studies and Analyses | Read moreNew Risk Variant for Atopic Dermatitis Identified
In a large genome-wide association study the researchers scanned the genomes of more than 9600 participants from Germany, Poland and the Czech Republic."Our findings cast new light on the...
Life Sciences | Read moreSpecific detection of <i>Mycobacterium avium</i> ssp. <i>paratuberculosis</i> (MAP)
Up to now, the detection of Mycobacterium avium ssp. paratuberculosis is very difficult and infections can unfortunately only be confirmed in a very late stage. Consequently, from time to time contami...
Technology Offerings | Read moreNew gene-searching method uncovers possible new targets for Crohn's disease drugs
Discovering the different genes that contribute to a complex disease is like searching in the proverbial haystack for an unknown number of needles--some much smaller than others, often blending into t...
Life Sciences | Read more
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