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An Atomic-level Look at an HIV Accomplice
Now, scientists at the University of Michigan have determined the atomic-level, three-dimensional structure of a SEVI precursor known as PAP248-286 and discovered how it damages cell membranes to make...
Health and Medicine |
Read moreScientists find molecular trigger that helps prevent aging and disease
An answer lies in a two-part study led by Charles Mobbs, PhD, Professor of Neuroscience and of Geriatrics and Palliative Medicine at Mount Sinai School of Medicine, published in the November 17 editio...
Life Sciences | Read moreMouse gene suppresses Alzheimer's plaques and tangles
Investigators at Burnham Institute for Medical Research (Burnham) and colleagues have identified a novel mouse gene (Rps23r1) that reduces the accumulation of two toxic proteins that are major players...
Life Sciences | Read moreAmyloid beta protein gets bum rap
While too much amyloid beta protein in the brain is linked to the development of Alzheimer's disease, not enough of the protein in healthy brains can cause learning problems and forgetfulness, Sa...
Health and Medicine | Read moreHybrid Molecules Show Promise for Exploring, Treating Alzheimer's
In order to answer that key question and develop new approaches to preventing the damage, scientists must first understand how amyloid-beta forms the telltale clumps.University of Michigan res...
Life Sciences | Read moreManipulating Brain Inflammation May Help Clear Brain of Amyloid Plaques
In fact, inflammation helps clear the brain of these noxious amyloid plaques early in the disease development, as seen from studies in mice that are predisposed to the disorder, say the researchers in...
Life Sciences | Read moreDiagnosis and treatment of Alzheimer´s and other neurodementing dseases
A-beta-autoantibodies were isolated from the serum of Alzheimer patients. The cDNA and amino acid sequences of the variable regions of the heavy and the light chains were determined and all possible p...
Technology Offerings | Read moreProtein engineering advancing Alzheimer's research
Alzheimer's disease is the most common form of dementia. In the 60-64 age group, one percent have the disorder, and among people age 85 and older, 25 percent are affected. At present there is no ...
Life Sciences | Read moreAlzheimer mice: Microglia cells are neither involved in formation nor clearance of amyloid deposits
In the brains of Alzheimer patients deposits of patholgical amyloid-beta protein, so-called amyloid plaques, are found. Since amyloid-beta protein plays a key role in the pathogenesis of Alzheimer...
Life Sciences | Read moreScientists remove amyloid plaques from brains of live animals with Alzheimer's disease
A breakthrough discovery by scientists from the Mayo Clinic in Jacksonville, FL, may lead to a new treatment for Alzheimer's Disease that actually removes amyloid plaques—considered a hallmark of...
Life Sciences | Read moreEnzyme may be a key to Alzheimer's-related cell death
Sandra Rossie, a professor of biochemistry, found that increasing the amount of protein phosphatase 5, or PP5, in rat neural cells resulted in less cell death associated with reactive oxygen species, ...
Life Sciences | Read moreNew Findings About Brain Proteins Suggest Possible Way to Fight Alzheimer’s
The findings, available online in the journal Proceedings of the National Academy of Sciences, suggest a promising new tactic against the devastating illness, the researchers said.The harmful ...
Health and Medicine | Read moreFirst direct information about the prion¹s molecular structure reported
In addition, the study has revealed surprisingly large structural differences between natural prions and the closest synthetic analogs that scientists have created in the lab. Prio...
Life Sciences | Read moreNew marker for Alzheimer's discovered
The substance is a beta-amyloid protein called Abeta16. The thesis shows in two independent studies that Alzheimer's patients have higher levels of the protein in their spinal fluid than do healt...
Life Sciences | Read moreBreakthrough in Alzheimer's research
The results were published in this week's edition of the Journal of the American Medical Association (JAMA).Alzheimer's is one of the most common dementia disorders. Around 160,000 p...
Health and Medicine | Read more
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