Home Special Topics Technology Offerings Content

Synthetic K receptor agonist for pain therapy - Novel class of k selective opioids for peripheral pain treatment

next article

22.02.2008

Natural and synthetic opioids are effective and widely used drugs for the treatment of acute, post-operative or malignant pain. These drugs interact predominantly with μ-opioid receptors in the central nervous system. While being strong analgesics, these drugs also cause severe side effects due to their interaction with μ-opioid receptors in the brain. This limits the use of currently available opioids for palliative care. Not many drugs are available for the treatment of severe peripheral, chronic, neuropathic or non-malignant pain. However, k-opioid receptor agonists with high k receptor affinity and selectivity, which cannot pass the blood brain barrier, are suitable for this purpose. At the University of Münster, a new class of compounds with high k receptor affinity and selectivity as well as strong analgesic effects has been developed.

Further Information: PDF

PROvendis GmbH
Phone: +49 (0)208/94105 0

Contact
Dipl.-Ing. Alfred Schillert

As Germany's association of technology- and patenttransfer agencies TechnologieAllianz e.V. is offering businesses access to the entire range of innovative research results of almost all German universities and numerous non-university research institutions. More than 2000 technology offers of 14 branches are beeing made accessable to businesses in order to assure your advance on the market. At www.technologieallianz.de a free, fast and non-bureaucratic access to all further offers of the German research landscape is offered to our members aiming to sucessfully transfer technologies.

info@technologieallianz.de | Source: TechnologieAllianz e.V.
Further information: www.technologieallianz.de/angebote.php?sort=sag&id=1221&lang=en
www.technologieallianz.de

next article