Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Treatment of Kynurenin-producing Tumors with AhR Antagonists

31.01.2013
Activation of the aryl hydrocarbon receptor (AHR) by environmental xenobiotic toxins has been implicated in a variety of cellular processes such as embryogenesis, transformation, tumorigenesis and inflammation. The TDO-AHR pathway is active in human brain tumors and associated with malignant progression and poor survival. As Kyn is produced during cancer progression and inflammation in the local microenvironment in amounts sufficient for activating the human AHR, these results can be used to develop a specific chemotherapy to manipulate AhR activated signal pathways in susceptible cancer cells. Using this mechanism more treatment opportunities can be used and different tumor types can be treated by AhR related drugs.

Further Information: PDF

Deutsches Krebsforschungszentrum DKFZ
Phone: +49-6221-42 2955

Contact
Dr. Ruth Herzog

info@technologieallianz.de | TechnologieAllianz e.V.
Further information:
http://www.technologieallianz.de/angebote.php?sort=sag&id=2985&lang=en
http://www.technologieallianz.de

More articles from Technology Offerings:

nachricht Method for production of itaconic acid
04.03.2015 | TechnologieAllianz e.V.

nachricht Versatile wheeled stretcher for rescuing of persons
03.03.2015 | TechnologieAllianz e.V.

All articles from Technology Offerings >>>

The most recent press releases about innovation >>>

Anzeige

Anzeige

Event News

70 Nobel laureates and 672 young scientists expected at Lindau

04.03.2015 | Event News

Registration open: 11th X-ray Forum for Customers of GE’s Digital Radiography and Industrial CT Inspection Technologies

04.03.2015 | Event News

ΣYSTEMS INTEGRATION in Finland focusses on high-tech printing

04.03.2015 | Event News

 
Latest News

Flexible and Functional – Prefabricated Façade Elements Simplify Building Renovation

04.03.2015 | Architecture and Construction

Emissions under control: comprehensive exhaust air analysis during laser processing of plastics

04.03.2015 | Ecology, The Environment and Conservation

Graphene, the wonder material, goes textile

04.03.2015 | Materials Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>