Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Thermomorphic Enzyme Recycling - One-phase process engineering and two-phase separation by temperature control

29.10.2010
Biocatalysts are playing an ever increasing role in economical and sustainable processes. A well-known example is the production of acrylamide by Mitsubishi Rayon which illustrates the advantages over the traditional chemical routes. However, only a few processes are known, in which the biocatalyst can be economically separated and re-used without loss of activity until now.

Well-established methods to obtain biocatalysts for re-use are e.g. the immobilization via adsorption onto suitable support materials, encapsulation in aqueous gels or cross-linked enzyme aggregates. All these recycling methods suffer from leaching of the enzyme and often from a substantial loss in activity. Laborious modifications of the enzyme are partly essential or highly-priced apparatus for efficient separation needs to be implemented. Another method is the usage of a liquid-liquid two-phase system, consisting of an aqueous medium and a water-immiscible organic solvent. But mass transfer limitations between the two immiscible phases are hardly narrowing the economically possible field of applications.

In the present invention, mass transfer limitations even with very non-polar compounds do not occur because a temperature-dependent miscibility gap of the selected solvent compounds is used. The reaction is carried out under monophasic conditions and cooling down leads to a biphasic system in which the catalyst phase can be simply separated from the product phase and used again. Thermomorphic Enzyme Recycling is an absolutely easy controllable process over a wide range of temperatures, solvent mixtures and operating conditions.

Further Information: PDF

PROvendis GmbH
Phone: +49 (0)208/94105 10

Contact
Dipl.-Ing. Alfred Schillert

info@technologieallianz.de | TechnologieAllianz e.V.
Further information:
http://www.technologieallianz.de/angebote.php?sort=sag&id=2178&lang=en
http://www.technologieallianz.de

More articles from Technology Offerings:

nachricht Peltier Adsorption Trap
29.11.2016 | TechnologieAllianz e.V.

nachricht Innovative method for producing analytical suspension cell lines
24.11.2016 | TechnologieAllianz e.V.

All articles from Technology Offerings >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Shape matters when light meets atom

Mapping the interaction of a single atom with a single photon may inform design of quantum devices

Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...

Im Focus: Novel silicon etching technique crafts 3-D gradient refractive index micro-optics

A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.

Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...

Im Focus: Quantum Particles Form Droplets

In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.

“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...

Im Focus: MADMAX: Max Planck Institute for Physics takes up axion research

The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.

The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...

Im Focus: Molecules change shape when wet

Broadband rotational spectroscopy unravels structural reshaping of isolated molecules in the gas phase to accommodate water

In two recent publications in the Journal of Chemical Physics and in the Journal of Physical Chemistry Letters, researchers around Melanie Schnell from the Max...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ICTM Conference 2017: Production technology for turbomachine manufacturing of the future

16.11.2016 | Event News

Innovation Day Laser Technology – Laser Additive Manufacturing

01.11.2016 | Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

 
Latest News

IHP presents the fastest silicon-based transistor in the world

05.12.2016 | Power and Electrical Engineering

InLight study: insights into chemical processes using light

05.12.2016 | Materials Sciences

High-precision magnetic field sensing

05.12.2016 | Power and Electrical Engineering

VideoLinks
B2B-VideoLinks
More VideoLinks >>>