Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Thermomorphic Enzyme Recycling - One-phase process engineering and two-phase separation by temperature control

29.10.2010
Biocatalysts are playing an ever increasing role in economical and sustainable processes. A well-known example is the production of acrylamide by Mitsubishi Rayon which illustrates the advantages over the traditional chemical routes. However, only a few processes are known, in which the biocatalyst can be economically separated and re-used without loss of activity until now.

Well-established methods to obtain biocatalysts for re-use are e.g. the immobilization via adsorption onto suitable support materials, encapsulation in aqueous gels or cross-linked enzyme aggregates. All these recycling methods suffer from leaching of the enzyme and often from a substantial loss in activity. Laborious modifications of the enzyme are partly essential or highly-priced apparatus for efficient separation needs to be implemented. Another method is the usage of a liquid-liquid two-phase system, consisting of an aqueous medium and a water-immiscible organic solvent. But mass transfer limitations between the two immiscible phases are hardly narrowing the economically possible field of applications.

In the present invention, mass transfer limitations even with very non-polar compounds do not occur because a temperature-dependent miscibility gap of the selected solvent compounds is used. The reaction is carried out under monophasic conditions and cooling down leads to a biphasic system in which the catalyst phase can be simply separated from the product phase and used again. Thermomorphic Enzyme Recycling is an absolutely easy controllable process over a wide range of temperatures, solvent mixtures and operating conditions.

Further Information: PDF

PROvendis GmbH
Phone: +49 (0)208/94105 10

Contact
Dipl.-Ing. Alfred Schillert

info@technologieallianz.de | TechnologieAllianz e.V.
Further information:
http://www.technologieallianz.de/angebote.php?sort=sag&id=2178&lang=en
http://www.technologieallianz.de

All articles from Technology Offerings >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Scientists spin artificial silk from whey protein

X-ray study throws light on key process for production

A Swedish-German team of researchers has cleared up a key process for the artificial production of silk. With the help of the intense X-rays from DESY's...

Im Focus: Quantum optical sensor for the first time tested in space – with a laser system from Berlin

For the first time ever, a cloud of ultra-cold atoms has been successfully created in space on board of a sounding rocket. The MAIUS mission demonstrates that quantum optical sensors can be operated even in harsh environments like space – a prerequi-site for finding answers to the most challenging questions of fundamental physics and an important innovation driver for everyday applications.

According to Albert Einstein's Equivalence Principle, all bodies are accelerated at the same rate by the Earth's gravity, regardless of their properties. This...

Im Focus: Traffic jam in empty space

New success for Konstanz physicists in studying the quantum vacuum

An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...

Im Focus: How gut bacteria can make us ill

HZI researchers decipher infection mechanisms of Yersinia and immune responses of the host

Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...

Im Focus: Interfacial Superconductivity: Magnetic and superconducting order revealed simultaneously

Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.

While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Sustainable Water use in Agriculture in Eastern Europe and Central Asia

19.01.2017 | Event News

12V, 48V, high-voltage – trends in E/E automotive architecture

10.01.2017 | Event News

2nd Conference on Non-Textual Information on 10 and 11 May 2017 in Hannover

09.01.2017 | Event News

 
Latest News

Breaking the optical bandwidth record of stable pulsed lasers

24.01.2017 | Physics and Astronomy

Choreographing the microRNA-target dance

24.01.2017 | Life Sciences

Spanish scientists create a 3-D bioprinter to print human skin

24.01.2017 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>